CA2204753A1 - Structures orthopediques synthetiques a base de collagene telles que des greffons, des tendons et autres - Google Patents

Structures orthopediques synthetiques a base de collagene telles que des greffons, des tendons et autres

Info

Publication number
CA2204753A1
CA2204753A1 CA002204753A CA2204753A CA2204753A1 CA 2204753 A1 CA2204753 A1 CA 2204753A1 CA 002204753 A CA002204753 A CA 002204753A CA 2204753 A CA2204753 A CA 2204753A CA 2204753 A1 CA2204753 A1 CA 2204753A1
Authority
CA
Canada
Prior art keywords
fibers
bundle
collagen
fiber
biodegradable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002204753A
Other languages
English (en)
Inventor
Frederick H. Silver
Yasushi Pedro. Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
University of Medicine and Dentistry of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Medicine and Dentistry of New Jersey filed Critical University of Medicine and Dentistry of New Jersey
Publication of CA2204753A1 publication Critical patent/CA2204753A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • D—TEXTILES; PAPER
    • D01—NATURAL OR MAN-MADE THREADS OR FIBRES; SPINNING
    • D01F—CHEMICAL FEATURES IN THE MANUFACTURE OF ARTIFICIAL FILAMENTS, THREADS, FIBRES, BRISTLES OR RIBBONS; APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OF CARBON FILAMENTS
    • D01F4/00—Monocomponent artificial filaments or the like of proteins; Manufacture thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/08—Muscles; Tendons; Ligaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/48—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with macromolecular fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00365—Proteins; Polypeptides; Degradation products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Composite Materials (AREA)
  • Rehabilitation Therapy (AREA)
  • Materials Engineering (AREA)
  • Textile Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

L'invention se rapporte à une fibre de collagène monofilament améliorée, reconstituée, biodégradable et biocompatible, présentant une résistance et une élasticité améliorées. Le procédé de fabrication de la fibre, qui comprend une étape de passage dans un bain d'eau et une étape de déshydratation, est également décrit. L'invention porte en outre sur plusieurs modes de réalisation de la fibre de collagène, permettant d'obtenir des greffons, des dispositifs prothétiques et des faisceaux de fibres dans lesquels les fibres sont tendues ensemble de manière à présenter pratiquement le même seuil de rupture, ainsi que sur les procédés associés. Les fibres selon l'invention, ou leurs variantes, peuvent être enrobées d'un polymère ou noyées dans un polymère qui les protège et les relie entre elles. En outre, on peut incorporer des protéoglycanes dans les fibres afin d'en augmenter la résistance finale à la traction.
CA002204753A 1994-11-07 1995-11-07 Structures orthopediques synthetiques a base de collagene telles que des greffons, des tendons et autres Abandoned CA2204753A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33554394A 1994-11-07 1994-11-07
US335,543 1994-11-07

Publications (1)

Publication Number Publication Date
CA2204753A1 true CA2204753A1 (fr) 1996-05-17

Family

ID=23312223

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002204753A Abandoned CA2204753A1 (fr) 1994-11-07 1995-11-07 Structures orthopediques synthetiques a base de collagene telles que des greffons, des tendons et autres

Country Status (4)

Country Link
EP (1) EP0793512A1 (fr)
AU (1) AU4280896A (fr)
CA (1) CA2204753A1 (fr)
WO (1) WO1996014095A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718012A (en) * 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
US8003705B2 (en) 1996-09-23 2011-08-23 Incept Llc Biocompatible hydrogels made with small molecule precursors
US6566406B1 (en) 1998-12-04 2003-05-20 Incept, Llc Biocompatible crosslinked polymers
US6083522A (en) * 1997-01-09 2000-07-04 Neucoll, Inc. Devices for tissue repair and methods for preparation and use thereof
US20030114061A1 (en) * 2001-12-13 2003-06-19 Kazuhisa Matsuda Adhesion preventive membrane, method of producing a collagen single strand, collagen nonwoven fabric and method and apparatus for producing the same
US7550004B2 (en) 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
EP1746952A1 (fr) * 2004-05-20 2007-01-31 Cook Incorporated Appareil endoluminal avec matériau de matrice extracellulaire et méthodes
EP1741453A3 (fr) * 2005-07-07 2007-01-17 Nipro Corporation Support à base de collagène, méthode de préparation et utilisation
ATE528024T1 (de) * 2006-12-27 2011-10-15 Shriners Hospitals Children Sehnen- oder bänderbioprothesen und herstellungsverfahren dafür
US8858633B2 (en) 2007-02-20 2014-10-14 Shriners Hospital For Children In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
US8067028B2 (en) 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
EP2194921B1 (fr) 2007-10-04 2018-08-29 TriVascular, Inc. Greffon vasculaire modulaire pour administration percutanée à profil réduit
JP5492097B2 (ja) 2008-02-22 2014-05-14 マイメディクス，インコーポレイテッド 手首、手及びその他の靱帯置換術又は修復術のために適切なバイオステープル
WO2009139871A2 (fr) 2008-05-16 2009-11-19 Mimedx, Inc. Constructions médicales de longueurs torsadées de fibres de collagène et leurs procédés de fabrication
BRPI0919506B1 (pt) 2008-09-30 2023-01-17 Trw Airbag Systems Gmbh Inflador para dispositivo de proteção de veículo
WO2010042207A2 (fr) 2008-10-09 2010-04-15 Mimedx, Inc. Procédés de réalisation de constructions médicales de fibre de collagène et de constructions médicales afférentes, y compris de guides nerveux et de timbres transdermiques
GB2466073A (en) * 2008-12-12 2010-06-16 Univ Manchester Tissue repair scaffold
US9636209B2 (en) 2011-03-08 2017-05-02 Mimedx Group, Inc. Collagen fiber ribbons with integrated fixation sutures and methods of making the same
US9694106B2 (en) 2011-07-11 2017-07-04 Mimedx Group, Inc. Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods
US8986378B2 (en) 2011-11-02 2015-03-24 Mimedx Group, Inc. Implantable collagen devices and related methods and systems of making same
US8992595B2 (en) 2012-04-04 2015-03-31 Trivascular, Inc. Durable stent graft with tapered struts and stable delivery methods and devices
US9498363B2 (en) 2012-04-06 2016-11-22 Trivascular, Inc. Delivery catheter for endovascular device
MX2019012005A (es) 2017-04-06 2020-02-12 Univ Carnegie Mellon Fabricación de aditivo basada en interfaz líquido-líquido.
US11583609B2 (en) 2018-08-08 2023-02-21 Mimedx Group, Inc. Collagen constructs and methods of making the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL76079A (en) * 1985-08-13 1991-03-10 Univ Ramot Collagen implants
US5306311A (en) * 1987-07-20 1994-04-26 Regen Corporation Prosthetic articular cartilage
US5263984A (en) * 1987-07-20 1993-11-23 Regen Biologics, Inc. Prosthetic ligaments
US5007934A (en) * 1987-07-20 1991-04-16 Regen Corporation Prosthetic meniscus
US5171273A (en) * 1989-01-13 1992-12-15 University Of Medicine And Dentistry Of New Jersey Synthetic collagen orthopaedic structures such as grafts, tendons and other structures
US5378469A (en) * 1990-04-06 1995-01-03 Organogenesis, Inc. Collagen threads
GB9206504D0 (en) * 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges as wound implants

Also Published As

Publication number Publication date
EP0793512A1 (fr) 1997-09-10
WO1996014095A1 (fr) 1996-05-17
AU4280896A (en) 1996-05-31

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Legal Events

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