CA2199372A1 - Procede d'inactivation photodynamique de contaminants du sang de nature virale et bacterienne a l'aide de sensibilisants a la coumarine ou la furocoumarine - Google Patents

Procede d'inactivation photodynamique de contaminants du sang de nature virale et bacterienne a l'aide de sensibilisants a la coumarine ou la furocoumarine

Info

Publication number
CA2199372A1
CA2199372A1 CA002199372A CA2199372A CA2199372A1 CA 2199372 A1 CA2199372 A1 CA 2199372A1 CA 002199372 A CA002199372 A CA 002199372A CA 2199372 A CA2199372 A CA 2199372A CA 2199372 A1 CA2199372 A1 CA 2199372A1
Authority
CA
Canada
Prior art keywords
photosensitizer
viral
biological solution
blood
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002199372A
Other languages
English (en)
Inventor
Raymond P. Goodrich, Jr.
Nagender Yerram
Brian Aquila
Matthew S. Platz
Samuel O. Sowemino-Coker
Sang Chul Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/311,125 external-priority patent/US5516629A/en
Priority claimed from US08/343,680 external-priority patent/US6251644B1/en
Application filed by Individual filed Critical Individual
Publication of CA2199372A1 publication Critical patent/CA2199372A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • A61K41/17—Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person by ultraviolet [UV] or infrared [IR] light, X-rays or gamma rays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ont peut inactiver de manière photodynamique les contaminants de nature virale, bactérienne ou parasitaire présents dans des compositions biologiques en mélangeant auxdites compositions des photosensibilisants halogénés de coumarine et de furocoumarine, puis en irradiant le mélange. La figure 1 représente le schéma énergétique proposé des photosensibilisants à action instantanée.
CA002199372A 1994-09-22 1995-09-21 Procede d'inactivation photodynamique de contaminants du sang de nature virale et bacterienne a l'aide de sensibilisants a la coumarine ou la furocoumarine Abandoned CA2199372A1 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US08/311,125 US5516629A (en) 1990-04-16 1994-09-22 Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US08/343,680 US6251644B1 (en) 1990-04-16 1994-11-22 Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US08/427,080 1995-04-21
US08/427,080 US5789601A (en) 1990-04-16 1995-04-21 Method of inactivation of viral and bacterial blood contaminants
US08/311,125 1995-06-05
US08/461,626 1995-06-05
US08/461,626 US5869701A (en) 1990-04-16 1995-06-05 Method of inactivation of viral and bacterial blood contaminants
US08/343,680 1995-06-05

Publications (1)

Publication Number Publication Date
CA2199372A1 true CA2199372A1 (fr) 1996-03-28

Family

ID=27502002

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002199372A Abandoned CA2199372A1 (fr) 1994-09-22 1995-09-21 Procede d'inactivation photodynamique de contaminants du sang de nature virale et bacterienne a l'aide de sensibilisants a la coumarine ou la furocoumarine

Country Status (5)

Country Link
EP (1) EP0782388A4 (fr)
AU (1) AU691672B2 (fr)
CA (1) CA2199372A1 (fr)
NO (1) NO971350L (fr)
WO (1) WO1996008965A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6077659A (en) * 1990-05-15 2000-06-20 New York Blood Center, Inc. Vitamin E and derivatives thereof prevent potassium ion leakage and other types of damage in red cells that are virus sterilized by phthalocyanines and light
AU703108B2 (en) * 1995-06-07 1999-03-18 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
DE19853425A1 (de) * 1998-11-19 2000-05-25 Martin Roecken Khellin-Zubereitung und deren Verwendung zur topischen Therapie der Psoriasis, ihrer Subtypen, Sonderformen, sowie zur topischen Therapie von Ekzemen
AUPP751298A0 (en) * 1998-12-04 1999-01-07 Csl Limited Inactivation of non-enveloped viruses
DE10031851B4 (de) * 2000-07-04 2005-10-13 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Photodynamische Behandlung und UV-B-Bestrahlung einer Thrombozyten-Suspension
US8580192B2 (en) 2006-10-31 2013-11-12 Ethicon, Inc. Sterilization of polymeric materials
US10842818B2 (en) 2014-07-23 2020-11-24 Cerus Corporation Methods for preparing platelet products
WO2016057965A1 (fr) 2014-10-10 2016-04-14 Cerus Corporation Compositions et méthodes de traitement de la fièvre hémorragique virale
EP3313418B1 (fr) 2015-06-26 2024-03-13 Cerus Corporation Compositions de cryoprécipités et leurs procédés de préparation
EP3364986B1 (fr) 2015-10-23 2023-12-13 Cerus Corporation Plasma cryogénique inactivé par des agents pathogènes et procédé pour son utilisation
SG11201805771XA (en) 2016-01-07 2018-08-30 Cerus Corp Systems and methods for preparation of platelets
WO2018161020A1 (fr) 2017-03-03 2018-09-07 Cerus Corporation Kits et méthodes de préparation de compositions de plaquettes inactivées par des agents pathogènes
MX2020003052A (es) 2017-09-20 2020-07-27 Cerus Corp Composiciones y metodos para inactivacion de patogenos de plaquetas.
WO2019133929A1 (fr) 2017-12-29 2019-07-04 Cerus Corporation Systèmes et procédés pour traiter de fluides biologiques
JP2022537457A (ja) 2019-06-22 2022-08-25 シーラス コーポレイション 生物学的流体処理システム
CA3143732A1 (fr) 2019-06-28 2020-12-30 Cerus Corporation Systeme et procedes permettant de mettre en ƒuvre un dispositif de traitement de fluide biologique

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091385A (en) * 1988-09-30 1992-02-25 Baylor Research Institute Pre-activated therapeutic agents derived from photoactive compounds
IL92996A (en) * 1989-01-10 1996-06-18 Bisaccia Emil Photovoltaic compounds as drugs for the treatment of viral infections and a method for the production of vaccines
EP0633786B1 (fr) * 1992-01-27 2001-08-01 Baxter International Inc. Procede d'inactivation des contaminants viraux, parasitaires et bacteriens du sang
AU703108B2 (en) * 1995-06-07 1999-03-18 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants

Also Published As

Publication number Publication date
AU3638595A (en) 1996-04-09
WO1996008965A1 (fr) 1996-03-28
AU691672B2 (en) 1998-05-21
NO971350L (no) 1997-05-22
NO971350D0 (no) 1997-03-21
EP0782388A1 (fr) 1997-07-09
EP0782388A4 (fr) 2000-03-08

Similar Documents

Publication Publication Date Title
US5789601A (en) Method of inactivation of viral and bacterial blood contaminants
US5798238A (en) Method of inactivation of viral and bacterial blood contaminants with quinolines as photosensitizer
US5587490A (en) Method of inactivation of viral and bacterial blood contaminants
US6087141A (en) Process for the sterilization of biological compositions and the product produced thereby
US5418130A (en) Method of inactivation of viral and bacterial blood contaminants
US5955256A (en) Method of inactivation of viral and bacterial blood contaminants
AU691672B2 (en) Photodynamic inactivation of viral and bacterial blood contaminants with halogenated coumarin and furocoumarin sensitizers
US5981163A (en) Process for the sterilization of biological compositions using irradiation and quenchers of type I and type II photodynamic reactions
AU699805B2 (en) Compounds for the photodecontamination of pathogens in blood
US6194139B1 (en) Methods for photodecontamination of pathogens in blood
US6548242B2 (en) Process for the sterilization of biological compositions and the product thereby
DE69434445T2 (de) Verfahren zur sterilisation biologischer zusammensetzungen und das dabei erhaltene produkt
CA2042494C (fr) Inactivation photodynamique de virus en compositions cellulaires
WO1996014739A1 (fr) Composes servant a la photodecontamination d'agents pathogenes dans le sang
US6004742A (en) Method for inactivation of pathogens in platelets using 4' and 5' primary amino-substituted psoralens
US6251644B1 (en) Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
AU703108B2 (en) Method of inactivation of viral and bacterial blood contaminants
Horowitz et al. Strategies for viral inactivation
JPH10506391A (ja) ハロゲン化クマリンおよびフロクマリン増感剤を用いるウイルス性および細菌性血液混入物の光力学的不活化
Kagan Synthesis of photoactive psoralen derivatives and evaluation of their potential as antiviral agents

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead