CA2197867C - Systeme therapeutique transdermique renfermant de l'oestradiol et des additifs hydrophiles - Google Patents

Systeme therapeutique transdermique renfermant de l'oestradiol et des additifs hydrophiles Download PDF

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Publication number
CA2197867C
CA2197867C CA002197867A CA2197867A CA2197867C CA 2197867 C CA2197867 C CA 2197867C CA 002197867 A CA002197867 A CA 002197867A CA 2197867 A CA2197867 A CA 2197867A CA 2197867 C CA2197867 C CA 2197867C
Authority
CA
Canada
Prior art keywords
estradiol
transdermal therapeutic
therapeutic system
matrix
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002197867A
Other languages
English (en)
Other versions
CA2197867A1 (fr
Inventor
Walter Muller
Michael Horstmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LTS Lohmann Therapie Systeme AG
Original Assignee
LTS Lohmann Therapie Systeme AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4429667A external-priority patent/DE4429667C2/de
Application filed by LTS Lohmann Therapie Systeme AG filed Critical LTS Lohmann Therapie Systeme AG
Publication of CA2197867A1 publication Critical patent/CA2197867A1/fr
Application granted granted Critical
Publication of CA2197867C publication Critical patent/CA2197867C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un système thérapeutique transdermique contenant de l'oestradiol comme principe actif et comprenant plusieurs couches: une couche dorsale imperméable au principe actif et à l'humidité, une couche de matrice renfermant le principe actif et, le cas échéant, une couche de protection détachable recouvrant la matrice. L'invention se caractérise en ce que la matrice renferme de la glycérine contenant au maximum 1 % en poids d'eau ou pratiquement sans eau.
CA002197867A 1994-08-20 1995-08-12 Systeme therapeutique transdermique renfermant de l'oestradiol et des additifs hydrophiles Expired - Fee Related CA2197867C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4429667.3 1994-08-20
DE4429667A DE4429667C2 (de) 1994-08-20 1994-08-20 Estradiol-TTS mit wasserbindenden Zusätzen und Verfahren zu seiner Herstellung
PCT/EP1995/003201 WO1996005814A1 (fr) 1994-08-20 1995-08-12 Systeme therapeutique transdermique contenant de l'×stradiol avec des additifs hydrophiles

Publications (2)

Publication Number Publication Date
CA2197867A1 CA2197867A1 (fr) 1996-02-29
CA2197867C true CA2197867C (fr) 2006-08-01

Family

ID=36764275

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002197867A Expired - Fee Related CA2197867C (fr) 1994-08-20 1995-08-12 Systeme therapeutique transdermique renfermant de l'oestradiol et des additifs hydrophiles

Country Status (1)

Country Link
CA (1) CA2197867C (fr)

Also Published As

Publication number Publication date
CA2197867A1 (fr) 1996-02-29

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Effective date: 20130813