CA2192196A1 - Modified siphons for improved metering precision - Google Patents
Modified siphons for improved metering precisionInfo
- Publication number
- CA2192196A1 CA2192196A1 CA002192196A CA2192196A CA2192196A1 CA 2192196 A1 CA2192196 A1 CA 2192196A1 CA 002192196 A CA002192196 A CA 002192196A CA 2192196 A CA2192196 A CA 2192196A CA 2192196 A1 CA2192196 A1 CA 2192196A1
- Authority
- CA
- Canada
- Prior art keywords
- chamber
- siphons
- metering precision
- improved metering
- siphon
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/07—Centrifugal type cuvettes
Landscapes
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Centrifugal Separators (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Optical Measuring Cells (AREA)
Abstract
The present invention provides centrifu-gal force rotors for delivering a premeasured volume of liquid to a chamber in the rotor. In particular the rotors comprise siphons (134) for delivering a premeasured volume of liquid be-tween a first and a second chamber (136) in the rotor. The siphons (134) of the invention are designed such that the inlet (138) of the siphon on the first chamber is radially outward of the siphon outlet (139) on the second cham-ber (136). The first chamber is emptied to a level equivalent to the radial position of the siphon outlet (139).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25440694A | 1994-06-06 | 1994-06-06 | |
US08/254,406 | 1994-06-06 | ||
PCT/US1995/007145 WO1995033986A1 (en) | 1994-06-06 | 1995-06-05 | Modified siphons for improved metering precision |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2192196A1 true CA2192196A1 (en) | 1995-12-14 |
CA2192196C CA2192196C (en) | 2004-11-23 |
Family
ID=22964194
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002192196A Expired - Lifetime CA2192196C (en) | 1994-06-06 | 1995-06-05 | Modified siphons for improved metering precision |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0764266A4 (en) |
JP (3) | JPH10501340A (en) |
CA (1) | CA2192196C (en) |
WO (1) | WO1995033986A1 (en) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5627041A (en) * | 1994-09-02 | 1997-05-06 | Biometric Imaging, Inc. | Disposable cartridge for an assay of a biological sample |
US6709869B2 (en) | 1995-12-18 | 2004-03-23 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system |
US6143248A (en) * | 1996-08-12 | 2000-11-07 | Gamera Bioscience Corp. | Capillary microvalve |
AU5895898A (en) | 1996-12-20 | 1998-07-17 | Gamera Bioscience Corporation | An affinity binding-based system for detecting particulates in a fluid |
US6632399B1 (en) | 1998-05-22 | 2003-10-14 | Tecan Trading Ag | Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system for performing biological fluid assays |
JP3469585B2 (en) | 1997-05-23 | 2003-11-25 | ガメラ バイオサイエンス コーポレイション | Apparatus and method for using centripetal acceleration to drive flow motion in microfluidics systems |
JP3969091B2 (en) * | 1999-06-23 | 2007-08-29 | 株式会社日立製作所 | Centrifuge and sample preparation apparatus using the same |
KR20020021810A (en) | 1999-08-11 | 2002-03-22 | 야마모토 카즈모토 | Analyzing cartridge and liquid feed control device |
WO2002043866A2 (en) * | 2000-12-01 | 2002-06-06 | Burstein Technologies, Inc. | Apparatus and methods for separating components of particulate suspension |
WO2002046721A2 (en) | 2000-12-08 | 2002-06-13 | Burstein Technologies, Inc. | Optical discs for measuring analytes |
US7054258B2 (en) | 2000-12-08 | 2006-05-30 | Nagaoka & Co., Ltd. | Optical disc assemblies for performing assays |
US7091034B2 (en) | 2000-12-15 | 2006-08-15 | Burstein Technologies, Inc. | Detection system for disk-based laboratory and improved optical bio-disc including same |
US7759067B2 (en) | 2001-03-19 | 2010-07-20 | Gyros Patent Ab | Method for determining the amount of an analyte with a disc-shaped microfluidic device |
US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
WO2003087827A2 (en) | 2001-04-11 | 2003-10-23 | Burstein Technologies, Inc. | Multi-parameter assays including analysis discs and methods relating thereto |
US6919058B2 (en) | 2001-08-28 | 2005-07-19 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
WO2003018198A1 (en) | 2001-08-28 | 2003-03-06 | Gyros Ab | Retaining microfluidic microcavity and other microfluidic structures |
US7189368B2 (en) | 2001-09-17 | 2007-03-13 | Gyros Patent Ab | Functional unit enabling controlled flow in a microfluidic device |
CN100549696C (en) * | 2001-12-14 | 2009-10-14 | 爱科来株式会社 | Sample measuring device |
JP3952019B2 (en) * | 2001-12-28 | 2007-08-01 | 株式会社日立ハイテクノロジーズ | Extraction apparatus, chemical analysis apparatus, and chemical analysis method |
CN1551982A (en) * | 2002-05-08 | 2004-12-01 | 株式会社日立高新技术 | Chemical analysis equipment and gene diagnosis equipment |
US7384602B2 (en) | 2002-05-08 | 2008-06-10 | Hitachi High-Technologies Corporation | Chemical analysis apparatus and genetic diagnostic apparatus |
JP4210783B2 (en) | 2002-09-26 | 2009-01-21 | アークレイ株式会社 | Analysis tool |
JP4262466B2 (en) | 2002-10-28 | 2009-05-13 | アークレイ株式会社 | Analysis tool and analyzer |
EP1600778B1 (en) * | 2003-02-19 | 2013-07-24 | Japan Science and Technology Agency | Blood analysis device and blood analysis method |
US7390464B2 (en) | 2003-06-19 | 2008-06-24 | Burstein Technologies, Inc. | Fluidic circuits for sample preparation including bio-discs and methods relating thereto |
JP4619224B2 (en) * | 2005-07-27 | 2011-01-26 | パナソニック株式会社 | Rotational analysis device |
DE102005048260A1 (en) * | 2005-10-07 | 2007-04-12 | Albert-Ludwigs-Universität Freiburg | A method and apparatus for handling a liquid sample using rotation with a time-varying rotary vector |
DE102005048233A1 (en) * | 2005-10-07 | 2007-04-12 | Albert-Ludwigs-Universität Freiburg | Apparatus and method for handling a liquid sample using a siphon structure |
JP4531677B2 (en) * | 2005-10-24 | 2010-08-25 | パナソニック株式会社 | Assay method, sensor device for implementing the same, and measuring device for sensor device |
JPWO2007116909A1 (en) * | 2006-04-04 | 2009-08-20 | パナソニック株式会社 | Sample solution analysis panel |
US20100086990A1 (en) * | 2007-03-02 | 2010-04-08 | Corbett Research Pty Ltd | Apparatus and method for nucleic acid amplification |
KR100858091B1 (en) * | 2007-04-24 | 2008-09-10 | 삼성전자주식회사 | Centrifugal force-based microfluidic device having sample distribution structure and microfluidic system including the microfluidic device |
EP2072131B1 (en) | 2007-12-13 | 2015-04-22 | Roche Diagnostics GmbH | Microfluid element for mixing a fluid into a reagent |
WO2009111461A2 (en) * | 2008-03-04 | 2009-09-11 | University Of Utah Research Foundation | Microfluidic flow cell |
CN103487594B (en) | 2008-07-17 | 2015-02-18 | 松下健康医疗器械株式会社 | Analyzing device, and analyzing method using the analyzing device |
KR101099495B1 (en) * | 2008-10-14 | 2011-12-28 | 삼성전자주식회사 | Centrifugal force-based microfluidic device, method of manufacturing the same and sample analysis method using the same |
GB2464721C (en) | 2008-10-23 | 2013-08-14 | Biosurfit Sa | Jet deflection device |
GB2466644B (en) * | 2008-12-30 | 2011-05-11 | Biosurfit Sa | Liquid handling |
JP5174723B2 (en) | 2009-03-12 | 2013-04-03 | パナソニック株式会社 | Analytical device |
GB2476474B (en) | 2009-12-22 | 2012-03-28 | Biosurfit Sa | Surface plasmon resonance detection system |
GB2479139A (en) | 2010-03-29 | 2011-10-05 | Biosurfit Sa | A liquid distribution and metering device |
EP2486978A1 (en) | 2010-10-28 | 2012-08-15 | Roche Diagnostics GmbH | Microfluid test carrier for separating a fluid volume in partial volumes |
EP2455162A1 (en) | 2010-10-29 | 2012-05-23 | Roche Diagnostics GmbH | Microfluidic element for analysing a fluid sample |
EP2684022B1 (en) * | 2011-03-08 | 2017-09-27 | Universite Laval | Fluidic centripetal device |
EP2709761B1 (en) * | 2011-05-18 | 2019-08-14 | DiaSorin S.p.A. | Systems and methods for volumetric metering on a sample processing device |
CN105170203B (en) | 2011-05-18 | 2017-07-18 | 3M创新有限公司 | Material system and method present in sample processing apparatus of the selected volume of detection |
BR112013027990B1 (en) | 2011-05-18 | 2020-11-03 | Diasorin S.P.A. | valve structure in a sample processing device and method for operating valves in a sample processing device |
WO2013083822A1 (en) | 2011-12-08 | 2013-06-13 | Biosurfit S.A. | Sequential aliqoting and determination of an indicator of sedimentation rate |
EP2878951B1 (en) | 2012-07-24 | 2019-11-20 | PHC Holdings Corporation | Analyzing device |
ES2686359T3 (en) * | 2013-04-15 | 2018-10-17 | Becton, Dickinson And Company | Biological fluid collection device |
USD799715S1 (en) | 2015-10-23 | 2017-10-10 | Gene POC, Inc. | Fluidic centripetal device |
AU2017289187B2 (en) * | 2016-06-27 | 2022-04-07 | Zoetis Services Llc | Devices with modified conduits |
WO2018165440A1 (en) * | 2017-03-08 | 2018-09-13 | Northwestern University | Devices, systems, and methods for specimen preparation and analysis using capillary and centrifugal forces |
CN112169853B (en) * | 2020-12-01 | 2021-02-26 | 南京岚煜生物科技有限公司 | Multifunctional microfluidic detection chip |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2572533B1 (en) * | 1984-10-26 | 1986-12-26 | Guigan Jean | METHOD FOR CARRYING OUT THE MEDICAL ANALYSIS OF A LIQUID SAMPLE USING AT LEAST ONE LIQUID REAGENT AND DEVICE FOR CARRYING OUT THE METHOD |
FR2575293B1 (en) * | 1984-12-21 | 1987-03-20 | Inovelf Sa | DYNAMIC PIPETTING ROTOR FOR CENTRIFUGAL ANALYSIS DEVICE |
FR2579756B1 (en) * | 1985-03-26 | 1987-05-07 | Guigan Jean | METHOD FOR PERFORMING BIOLOGICAL ANALYSIS USING IMMUNOLOGICAL REACTIONS AND DEVICE FOR CARRYING OUT SAID METHOD |
US4999304A (en) * | 1987-12-28 | 1991-03-12 | Miles Inc. | Dynamic braking centrifuge |
US5160702A (en) * | 1989-01-17 | 1992-11-03 | Molecular Devices Corporation | Analyzer with improved rotor structure |
US5256376A (en) * | 1991-09-12 | 1993-10-26 | Medical Laboratory Automation, Inc. | Agglutination detection apparatus |
US5304348A (en) * | 1992-02-11 | 1994-04-19 | Abaxis, Inc. | Reagent container for analytical rotor |
AU4047493A (en) * | 1992-04-02 | 1993-11-08 | Abaxis, Inc. | Analytical rotor with dye mixing chamber |
US5591643A (en) | 1993-09-01 | 1997-01-07 | Abaxis, Inc. | Simplified inlet channels |
-
1995
- 1995-06-05 JP JP8501264A patent/JPH10501340A/en active Pending
- 1995-06-05 CA CA002192196A patent/CA2192196C/en not_active Expired - Lifetime
- 1995-06-05 EP EP95922222A patent/EP0764266A4/en not_active Withdrawn
- 1995-06-05 WO PCT/US1995/007145 patent/WO1995033986A1/en active Application Filing
-
2006
- 2006-08-17 JP JP2006222178A patent/JP4178169B2/en not_active Expired - Lifetime
-
2008
- 2008-01-25 JP JP2008014351A patent/JP2008157960A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2192196C (en) | 2004-11-23 |
JP4178169B2 (en) | 2008-11-12 |
JP2008157960A (en) | 2008-07-10 |
WO1995033986A1 (en) | 1995-12-14 |
EP0764266A4 (en) | 1998-08-05 |
JP2006317467A (en) | 2006-11-24 |
EP0764266A1 (en) | 1997-03-26 |
JPH10501340A (en) | 1998-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20150605 |