CA2188599A1 - Taxane class derivative based pharmaceutical compositions - Google Patents

Taxane class derivative based pharmaceutical compositions

Info

Publication number
CA2188599A1
CA2188599A1 CA002188599A CA2188599A CA2188599A1 CA 2188599 A1 CA2188599 A1 CA 2188599A1 CA 002188599 A CA002188599 A CA 002188599A CA 2188599 A CA2188599 A CA 2188599A CA 2188599 A1 CA2188599 A1 CA 2188599A1
Authority
CA
Canada
Prior art keywords
pharmaceutical compositions
docetaxel
based pharmaceutical
derivative based
taxane class
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002188599A
Other languages
French (fr)
Other versions
CA2188599C (en
Inventor
Manfred Durr
Jorg-Christian Hager
Armin Wendel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Manfred Durr
Jorg-Christian Hager
Armin Wendel
Rhone-Poulenc Rorer S.A.
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9404951A external-priority patent/FR2718963B1/en
Application filed by Manfred Durr, Jorg-Christian Hager, Armin Wendel, Rhone-Poulenc Rorer S.A., Aventis Pharma S.A. filed Critical Manfred Durr
Publication of CA2188599A1 publication Critical patent/CA2188599A1/en
Application granted granted Critical
Publication of CA2188599C publication Critical patent/CA2188599C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)

Abstract

Composition pharmaceutique stable et fortement concentrée en principe actif de la classe des taxoïdes comme le docétaxel ou les dérivés du docétaxel, caractérisée en ce qu'elle comprend un agent thérapeutique de la classe des taxoïdes comme le docétaxel ou les dérivés du docétaxel, un ou plusieurs phospholipides insaturés et une faible quantité d'un ou plusieurs phospholipides négatifs.Stable and highly concentrated pharmaceutical composition of active principle from the class of taxoids such as docetaxel or docetaxel derivatives, characterized in that it comprises a therapeutic agent from the class of taxoids such as docetaxel or derivatives of docetaxel, one or more unsaturated phospholipids and a small amount of one or more negative phospholipids.

CA002188599A 1994-04-25 1995-04-24 Taxane class derivative based pharmaceutical compositions Expired - Fee Related CA2188599C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/04951 1994-04-25
FR9404951A FR2718963B1 (en) 1994-04-25 1994-04-25 New pharmaceutical composition based on taxoids.
PCT/FR1995/000532 WO1995028923A1 (en) 1994-04-25 1995-04-24 Taxane class derivative based pharmaceutical compositions

Publications (2)

Publication Number Publication Date
CA2188599A1 true CA2188599A1 (en) 1995-11-02
CA2188599C CA2188599C (en) 2006-10-31

Family

ID=37395776

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002188599A Expired - Fee Related CA2188599C (en) 1994-04-25 1995-04-24 Taxane class derivative based pharmaceutical compositions

Country Status (1)

Country Link
CA (1) CA2188599C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114588272A (en) * 2022-04-08 2022-06-07 皖西学院 NO-loaded docetaxel nano-drug and preparation method and application thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114588272A (en) * 2022-04-08 2022-06-07 皖西学院 NO-loaded docetaxel nano-drug and preparation method and application thereof
CN114588272B (en) * 2022-04-08 2023-05-26 皖西学院 NO-loaded docetaxel nano-drug and preparation method and application thereof

Also Published As

Publication number Publication date
CA2188599C (en) 2006-10-31

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20150424