CA2184691A1 - Derives de l-n6-(1-iminoethyl)lysine, utiles comme inhibiteurs de l'oxyde nitrique synthetase - Google Patents

Derives de l-n6-(1-iminoethyl)lysine, utiles comme inhibiteurs de l'oxyde nitrique synthetase

Info

Publication number
CA2184691A1
CA2184691A1 CA002184691A CA2184691A CA2184691A1 CA 2184691 A1 CA2184691 A1 CA 2184691A1 CA 002184691 A CA002184691 A CA 002184691A CA 2184691 A CA2184691 A CA 2184691A CA 2184691 A1 CA2184691 A1 CA 2184691A1
Authority
CA
Canada
Prior art keywords
iminoethyl
nitric oxide
oxide synthase
synthase inhibitors
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002184691A
Other languages
English (en)
Other versions
CA2184691C (fr
Inventor
E. Ann Hallinan
Foe S. Tjoeng
Kam F. Fok
Timothy J. Hagen
Mihaly V. Toth
Sofya Tsymbalov
Barnett S. Pitzele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1995/002669 external-priority patent/WO1995024382A1/fr
Publication of CA2184691A1 publication Critical patent/CA2184691A1/fr
Application granted granted Critical
Publication of CA2184691C publication Critical patent/CA2184691C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002184691A 1994-03-10 1995-03-08 Derives de l-n6-(1-iminoethyl)lysine, utiles comme inhibiteurs de l'oxyde nitrique synthetase Expired - Fee Related CA2184691C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20909494A 1994-03-10 1994-03-10
US08/209,094 1994-03-10
PCT/US1995/002669 WO1995024382A1 (fr) 1994-03-10 1995-03-08 Derives de la l-n6-(1-iminoethyl)lysine utiles comme inhibiteurs de la synthetase generant de l'oxyde nitrique

Publications (2)

Publication Number Publication Date
CA2184691A1 true CA2184691A1 (fr) 1995-09-14
CA2184691C CA2184691C (fr) 2006-02-21

Family

ID=35929804

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002184691A Expired - Fee Related CA2184691C (fr) 1994-03-10 1995-03-08 Derives de l-n6-(1-iminoethyl)lysine, utiles comme inhibiteurs de l'oxyde nitrique synthetase

Country Status (1)

Country Link
CA (1) CA2184691C (fr)

Also Published As

Publication number Publication date
CA2184691C (fr) 2006-02-21

Similar Documents

Publication Publication Date Title
AU2115695A (en) L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors
AU4883096A (en) Nitric oxide synthase inhibitors
NZ229480A (en) Amino acid derivatives containing nitrogen-containing heterocycle, and pharmaceutical compositions
IE862404L (en) Hydroxamic acid derivatives
CA2327723A1 (fr) Derives bicycliques de l'acide hydroxamique
CA2201784A1 (fr) Procede et formulation pour stimuler la synthese de l'oxyde d'azote
GEP20012578B (en) (54) Heteroaryl Succinamides, Pharmaceutical Compositions Containing the Same and Methods for Treatment of the Diseases Caused by Metalloproteinase Activity
AU2515895A (en) Gel stick compositions comprising optically enriched gellants
MY117948A (en) Nitride oxide synthase inhibitors.
GEP20032896B (en) 4-Aminothiazole Derivatives, Containing Them Pharmaceutical Compositions Inhibiting Cyclin-Dependent Kinases and Methods for Treatment
MY132705A (en) Novel compounds with analgesic effect
ZA948669B (en) New pyrazine carboxamide derivatives the preparation thereof and their use in pharmaceutical compositions
NZ232695A (en) Amino acid derivatives and pharmaceutical compositions thereof
AU1937395A (en) Pharmaceutical compositions containing alkylthioalkanoic acids or derivatives thereof and their use in the treatment of mycobacterial infections and as antiseptic
AU3459789A (en) Aqueous compositions of pyroglutamic acid esters for topical application to human skin and hair
EP0441192A3 (en) Retroisosteric dipeptides, their preparation and use as renin inhibitors in pharmaceutical compositions
AU7263591A (en) Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors
NZ316735A (en) Amino alcohol derivatives of l-n6-(1-iminoethyl) lysine compositions containing these and there use as nitric oxide synthase inhibitors
CA2272880A1 (fr) Composition et procede permettant de reduire la sensation d'irritation de la peau
GEP19991872B (en) Novel Taxoids, Preparations Thereof, and Pharmaceutical Compositions Containing Same
EP0441191A3 (en) Retroisosteric dipeptides, their preparation and use as renin inhibitors in pharmaceutical compositions
NZ227976A (en) Heterocyclyl-substituted renin-inhibiting amino acid derivatives and pharmaceutical compositions
CA2184691A1 (fr) Derives de l-n6-(1-iminoethyl)lysine, utiles comme inhibiteurs de l'oxyde nitrique synthetase
IL124296A0 (en) Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase
AU7787694A (en) Pharmaceutical compositions containing nitric oxide synthase inhibitors and anti-cancer agents

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20080310