CA2184691A1 - L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors - Google Patents

L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

Info

Publication number
CA2184691A1
CA2184691A1 CA002184691A CA2184691A CA2184691A1 CA 2184691 A1 CA2184691 A1 CA 2184691A1 CA 002184691 A CA002184691 A CA 002184691A CA 2184691 A CA2184691 A CA 2184691A CA 2184691 A1 CA2184691 A1 CA 2184691A1
Authority
CA
Canada
Prior art keywords
iminoethyl
nitric oxide
oxide synthase
synthase inhibitors
derivatives useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002184691A
Other languages
French (fr)
Other versions
CA2184691C (en
Inventor
E. Ann Hallinan
Foe S. Tjoeng
Kam F. Fok
Timothy J. Hagen
Mihaly V. Toth
Sofya Tsymbalov
Barnett S. Pitzele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1995/002669 external-priority patent/WO1995024382A1/en
Publication of CA2184691A1 publication Critical patent/CA2184691A1/en
Application granted granted Critical
Publication of CA2184691C publication Critical patent/CA2184691C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

There is disclosed a novel amino glycol derivatives of L-N6-(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors.
CA002184691A 1994-03-10 1995-03-08 L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors Expired - Fee Related CA2184691C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20909494A 1994-03-10 1994-03-10
US08/209,094 1994-03-10
PCT/US1995/002669 WO1995024382A1 (en) 1994-03-10 1995-03-08 L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

Publications (2)

Publication Number Publication Date
CA2184691A1 true CA2184691A1 (en) 1995-09-14
CA2184691C CA2184691C (en) 2006-02-21

Family

ID=35929804

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002184691A Expired - Fee Related CA2184691C (en) 1994-03-10 1995-03-08 L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

Country Status (1)

Country Link
CA (1) CA2184691C (en)

Also Published As

Publication number Publication date
CA2184691C (en) 2006-02-21

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Legal Events

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Effective date: 20080310