CA2182274C - Antigenic preparation for treatment or prevention of helicobacter infection - Google Patents

Antigenic preparation for treatment or prevention of helicobacter infection Download PDF

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Publication number
CA2182274C
CA2182274C CA002182274A CA2182274A CA2182274C CA 2182274 C CA2182274 C CA 2182274C CA 002182274 A CA002182274 A CA 002182274A CA 2182274 A CA2182274 A CA 2182274A CA 2182274 C CA2182274 C CA 2182274C
Authority
CA
Canada
Prior art keywords
lps
helicobacter
vaccine composition
infection
felis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002182274A
Other languages
English (en)
French (fr)
Other versions
CA2182274A1 (en
Inventor
Christopher Vincent Doidge
Adrian Lee
Fiona Jane Buck
Elizabeth Pietrzykowski
Charles Alexander Quinn
Ian George Barr
Michael John Kleinig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CSL Ltd
UNSW Sydney
Original Assignee
CSL Ltd
UNSW Sydney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CSL Ltd, UNSW Sydney filed Critical CSL Ltd
Publication of CA2182274A1 publication Critical patent/CA2182274A1/en
Application granted granted Critical
Publication of CA2182274C publication Critical patent/CA2182274C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/121—Helicobacter (G); Campylobacter (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
CA002182274A 1994-02-21 1995-02-17 Antigenic preparation for treatment or prevention of helicobacter infection Expired - Fee Related CA2182274C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUAUPM3995 1994-02-21
AUPM3995A AUPM399594A0 (en) 1994-02-21 1994-02-21 Antigenic preparation for treatment or prevention of helicobacter infection
PCT/AU1995/000077 WO1995022563A1 (en) 1994-02-21 1995-02-17 Antigenic preparation for treatment or prevention of helicobacter infection

Publications (2)

Publication Number Publication Date
CA2182274A1 CA2182274A1 (en) 1995-08-24
CA2182274C true CA2182274C (en) 2007-05-22

Family

ID=3778612

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002182274A Expired - Fee Related CA2182274C (en) 1994-02-21 1995-02-17 Antigenic preparation for treatment or prevention of helicobacter infection

Country Status (10)

Country Link
US (1) US6663873B2 (https=)
EP (1) EP0804489B1 (https=)
JP (1) JPH10500102A (https=)
KR (1) KR100351534B1 (https=)
AT (1) ATE222930T1 (https=)
AU (2) AUPM399594A0 (https=)
CA (1) CA2182274C (https=)
DE (1) DE69527986T2 (https=)
NZ (2) NZ281146A (https=)
WO (1) WO1995022563A1 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPM399594A0 (en) * 1994-02-21 1994-03-17 Csl Limited Antigenic preparation for treatment or prevention of helicobacter infection
EP0792347B1 (en) * 1994-10-05 2005-11-23 Antex Biologics, Inc. Methods for producing enhanced antigenic helicobacter sp. and vaccines comprising same
US5897475A (en) * 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
AU693679B2 (en) * 1995-04-21 1998-07-02 Csl Limited Protective helicobacter antigens
NZ304756A (en) 1995-04-21 2000-02-28 Univ New South Wales Protective Helicobacter antigens and vaccine compositions containing them
AU6583398A (en) * 1997-03-26 1998-10-20 Avant Immunotherapeutics, Inc. Polypeptides which immunoreact with polyclonal antisera against (h. pylori)
GB9715702D0 (en) * 1997-07-24 1997-10-01 Univ Bristol Bacterial isolate
US6599509B2 (en) * 1997-09-02 2003-07-29 Massachusetts Institute Of Technology Compositions and methods comprising helicobacter antigens for treatment and prevention of inflammatory bowel disease
JP4054681B2 (ja) * 2001-02-21 2008-02-27 デンカ生研株式会社 ヘリコバクター・ピロリを認識する抗体、およびヘリコバクター・ピロリを検出する方法
DE102004024674A1 (de) * 2004-05-18 2005-12-15 Wolfgang Lorenz Mittel und Verfahren zur Diagnose, Prophylaxe und Therapie von Bindegewebserkrankungen
EP1930025B1 (en) 2005-08-05 2013-05-01 The University of Tokushima ANTIGEN-AND-DRUG VEHICLE WHICH ENABLES THE CHANGEOVER FROM THE SELECTIVE PRODUCTION OF IgA ANTIBODY TO THE PRODUCTION OF BOTH OF IgA AND IgG ANTIBODIES, AND TRANSNASAL/TRANSMUCOSAL VACCINE USING THE VEHICLE
TR201807924T4 (tr) 2013-01-17 2018-06-21 Arsanis Biosciences Gmbh MDR e. koli spesifik antikor.
JP6590413B2 (ja) 2014-02-06 2019-10-16 エックスフォー・ファーマシューティカルズ（オーストリア）ゲーエムべーハー 大腸菌特異的抗体配列
CN106535927B (zh) 2014-02-24 2019-09-20 葛兰素史密丝克莱恩生物有限公司 新颖多糖及其用途
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
CR20210522A (es) 2019-03-18 2021-12-17 Janssen Pharmaceuticals Inc Bioconjugados de antígenos–polisacáridos de e. coli, métodos de producción y métodos de utilización de los mismos
IL286467B2 (en) 2019-03-18 2026-02-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of polysaccharides E. coli o-antigen, preparations thereof and methods for using them
CN111467368B (zh) * 2020-04-13 2021-05-28 江南大学 含庚糖链的寡糖化合物在制备幽门螺旋杆菌疫苗中的应用
IL308201A (en) 2020-09-17 2024-01-01 Janssen Pharmaceuticals Inc Multivalent vaccine compositions and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU644121B2 (en) * 1989-12-04 1993-12-02 Auspharm International Limited Rapid in vitro test for helicobacter pylori using saliva
US5217872A (en) * 1990-02-27 1993-06-08 The United States Of America As Represented By The Department Of Health And Human Services Method for detection of borrelia burgdorferi antigens
US5098755A (en) * 1990-11-21 1992-03-24 Tanquary Albert C Textured thermoplastic elastomeric film, articles comprising same, and method of making such textured thermoplastic elastomeric film and articles
MX9301706A (es) 1992-04-13 1994-05-31 Oravax Inc Composicion de vacuna para el tratamiento de la infeccion por helicobacter.
US5580563A (en) * 1992-05-01 1996-12-03 Tam; James P. Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof
US6258359B1 (en) * 1993-05-19 2001-07-10 Institut Pasteur Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
KR100333113B1 (ko) * 1993-07-27 2002-11-27 시에스엘 리미티드 헬리코박터피롤리관련위십이지장질환의치료방법
US6406703B1 (en) * 1993-07-27 2002-06-18 Csl Limited Treatment of H. pylori associated gastroduodenal disease
CA2176237A1 (en) * 1993-11-10 1995-05-18 Richard P. Darveau Treatment of bacterially-induced inflammatory diseases
AUPM399594A0 (en) * 1994-02-21 1994-03-17 Csl Limited Antigenic preparation for treatment or prevention of helicobacter infection
AUPM612494A0 (en) * 1994-06-08 1994-06-30 Csl Limited Treatment or prevention of helicobacter infection
US5897475A (en) * 1994-10-05 1999-04-27 Antex Biologics, Inc. Vaccines comprising enhanced antigenic helicobacter spp.
NZ304756A (en) * 1995-04-21 2000-02-28 Univ New South Wales Protective Helicobacter antigens and vaccine compositions containing them
US5997881A (en) * 1995-11-22 1999-12-07 University Of Maryland, Baltimore Method of making non-pyrogenic lipopolysaccharide or A
AU3458299A (en) * 1998-03-31 1999-10-18 United States Of America, As Represented By The Secretary Of Agriculture, The Monoclonal antibodies against (campylobacter jejuni) and (campylobacter coli) outer membrane antigens
NZ509127A (en) * 1998-06-19 2004-01-30 Merieux Oravax Use of LT (E. coli) and CT (cholera toxin) for inducing immune responses against helicobacter infection

Also Published As

Publication number Publication date
EP0804489A1 (en) 1997-11-05
CA2182274A1 (en) 1995-08-24
AU693864B2 (en) 1998-07-09
EP0804489B1 (en) 2002-08-28
US20020122794A1 (en) 2002-09-05
US6663873B2 (en) 2003-12-16
NZ281146A (en) 1998-04-27
KR100351534B1 (ko) 2003-03-15
DE69527986D1 (de) 2002-10-02
AU1801195A (en) 1995-09-04
NZ329879A (en) 1999-10-28
ATE222930T1 (de) 2002-09-15
EP0804489A4 (https=) 1997-11-19
WO1995022563A1 (en) 1995-08-24
AUPM399594A0 (en) 1994-03-17
JPH10500102A (ja) 1998-01-06
DE69527986T2 (de) 2003-04-10
HK1004677A1 (en) 1998-12-04
KR970701209A (ko) 1997-03-17

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