CA2181815C - Procede pour determiner la quantite de lbp dans des fluides corporels - Google Patents

Procede pour determiner la quantite de lbp dans des fluides corporels Download PDF

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Publication number
CA2181815C
CA2181815C CA002181815A CA2181815A CA2181815C CA 2181815 C CA2181815 C CA 2181815C CA 002181815 A CA002181815 A CA 002181815A CA 2181815 A CA2181815 A CA 2181815A CA 2181815 C CA2181815 C CA 2181815C
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CA
Canada
Prior art keywords
lbp
concentration
endotoxin
binding protein
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002181815A
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English (en)
Other versions
CA2181815A1 (fr
Inventor
Mark Leslie White
Stephen Fitzhugh Carroll
Jeremy Kam-Kuen Ma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xoma Royalty Corp
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/186,811 external-priority patent/US5484705A/en
Application filed by Xoma Corp filed Critical Xoma Corp
Publication of CA2181815A1 publication Critical patent/CA2181815A1/fr
Application granted granted Critical
Publication of CA2181815C publication Critical patent/CA2181815C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Cette invention se rapporte à un procédé qui permet de déterminer la quantité de LBP (protéines de fixation des lipopolysaccharides) extracellulaires présente dans des fluides corporels, y compris le sang, chez un sujet, ce procédé consistant à effectuer un immunodosage des LBP sur du plasma prélevé sur ce sujet.
CA002181815A 1994-01-24 1995-01-24 Procede pour determiner la quantite de lbp dans des fluides corporels Expired - Fee Related CA2181815C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/186,811 1994-01-24
US08/186,811 US5484705A (en) 1994-01-24 1994-01-24 Method for quantifying lipopolysaccharide binding protein
PCT/US1995/000982 WO1995020163A1 (fr) 1994-01-24 1995-01-24 Procede pour determiner la quantite de lbp dans des fluides corporels

Publications (2)

Publication Number Publication Date
CA2181815A1 CA2181815A1 (fr) 1995-07-27
CA2181815C true CA2181815C (fr) 2006-08-22

Family

ID=36939151

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002181815A Expired - Fee Related CA2181815C (fr) 1994-01-24 1995-01-24 Procede pour determiner la quantite de lbp dans des fluides corporels

Country Status (1)

Country Link
CA (1) CA2181815C (fr)

Also Published As

Publication number Publication date
CA2181815A1 (fr) 1995-07-27

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Effective date: 20130124