CA2181089A1 - Piperidine Derivatives and Process for Their Production - Google Patents

Piperidine Derivatives and Process for Their Production

Info

Publication number
CA2181089A1
CA2181089A1 CA2181089A CA2181089A CA2181089A1 CA 2181089 A1 CA2181089 A1 CA 2181089A1 CA 2181089 A CA2181089 A CA 2181089A CA 2181089 A CA2181089 A CA 2181089A CA 2181089 A1 CA2181089 A1 CA 2181089A1
Authority
CA
Canada
Prior art keywords
hydrogen
production
substituents
hydroxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2181089A
Other languages
French (fr)
Other versions
CA2181089C (en
Inventor
Thomas E. D'ambra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Curia Global Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25677908&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2181089(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Priority claimed from CA002147126A external-priority patent/CA2147126C/en
Publication of CA2181089A1 publication Critical patent/CA2181089A1/en
Application granted granted Critical
Publication of CA2181089C publication Critical patent/CA2181089C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to substantially pure piperidine derivative compounds as shown below, wherein R1 is hydrogen or hydroxy; R2 is hydrogen; or R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; R3 is -COOH or -COOH4; R4 is an alkyl with 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents. A process of preparing such piperidine derivative compounds in substantially pure form is also disclosed.

(see formula I) or (see formula II)
CA002181089A 1993-06-24 1994-06-21 Piperidine derivatives and process for their production Expired - Lifetime CA2181089C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8310293A 1993-06-24 1993-06-24
US08/083,102 1993-06-24
CA002147126A CA2147126C (en) 1993-06-24 1994-06-21 Piperidine derivatives and process for their production

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002147126A Division CA2147126C (en) 1993-06-24 1994-06-21 Piperidine derivatives and process for their production

Publications (2)

Publication Number Publication Date
CA2181089A1 true CA2181089A1 (en) 1994-12-25
CA2181089C CA2181089C (en) 2000-05-23

Family

ID=25677908

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002254506A Expired - Lifetime CA2254506C (en) 1993-06-24 1994-06-21 Piperidine derivatives and process for their production
CA002181089A Expired - Lifetime CA2181089C (en) 1993-06-24 1994-06-21 Piperidine derivatives and process for their production

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002254506A Expired - Lifetime CA2254506C (en) 1993-06-24 1994-06-21 Piperidine derivatives and process for their production

Country Status (1)

Country Link
CA (2) CA2254506C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135571B2 (en) 1994-05-18 2006-11-14 Aventis Pharmaceuticals, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7135571B2 (en) 1994-05-18 2006-11-14 Aventis Pharmaceuticals, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US7138524B2 (en) 1994-05-18 2006-11-21 Aventis Pharmaceuticals, Inc. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
US7662835B2 (en) 1994-05-18 2010-02-16 Aventis Holdings, Inc. Methods of treating allergic reactions using an anhydrous form of antihistaminic piperidine derivatives
US7666881B2 (en) 1994-05-18 2010-02-23 Aventis Holdings, Inc. Methods of treating allergic reactions using hydrated forms of antihistaminic piperidine derivatives

Also Published As

Publication number Publication date
CA2254506A1 (en) 1995-01-05
CA2254506C (en) 2000-11-28
CA2181089C (en) 2000-05-23

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Effective date: 20140623