CA2180147A1 - Revetements a base d'oxyde de polyethylene reticule destines a ameliorer la compatibilite biologique d'appareils medicaux destines a etre implantes - Google Patents

Revetements a base d'oxyde de polyethylene reticule destines a ameliorer la compatibilite biologique d'appareils medicaux destines a etre implantes

Info

Publication number
CA2180147A1
CA2180147A1 CA002180147A CA2180147A CA2180147A1 CA 2180147 A1 CA2180147 A1 CA 2180147A1 CA 002180147 A CA002180147 A CA 002180147A CA 2180147 A CA2180147 A CA 2180147A CA 2180147 A1 CA2180147 A1 CA 2180147A1
Authority
CA
Canada
Prior art keywords
peo
medical device
aldehyde
functionalized
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002180147A
Other languages
English (en)
Inventor
Gerard Llanos
Mutlu Karakelle
Joe Milton Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Vision LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/340,671 external-priority patent/US5507804A/en
Application filed by Individual filed Critical Individual
Publication of CA2180147A1 publication Critical patent/CA2180147A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A61L2/206—Ethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08—Materials for coatings
    • A61L29/085—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Surgery (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Cette invention concerne des revêtements à base d'oxyde de polyéthylène donnant une meilleure compatibilité biologique aux appareils médicaux destinés à être implantés. Ces revêtements se composent d'une capsule de forme appropriée en oxyde de polyéthylène se fixant à une extrémité de l'appareil médical. Les composés d'oxyde de polyéthylène peuvent alors être réticulés de deux manières. Ces composés peuvent être exposés à une puissante source d'énergie pendant une période suffisamment longue pour qu'ils forment un réseau réticulé insoluble. On peut également faire réagir les extrémités libres et de forme appropriée de façon à obtenir un nombre suffisant de composés d'oxyde d'éthylène liés, ceci à l'aide d'un agent de réticulation dont les groupes fonctionnels réagissent vers les extrémités de forme appropriée de la chaîne d'oxyde d'éthylène liée. Ces revêtements à base d'oxyde d'éthylène peuvent supporter les processus de stérilisation d'oxyde d'éthylène tout en minimisant la perte de protéines ou la capacité de répulsion cellulaire.
CA002180147A 1994-11-16 1995-11-16 Revetements a base d'oxyde de polyethylene reticule destines a ameliorer la compatibilite biologique d'appareils medicaux destines a etre implantes Abandoned CA2180147A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US34068194A 1994-11-16 1994-11-16
US08/340,671 1994-11-16
US08/340,681 1994-11-16
US08/340,671 US5507804A (en) 1994-11-16 1994-11-16 Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices

Publications (1)

Publication Number Publication Date
CA2180147A1 true CA2180147A1 (fr) 1996-05-23

Family

ID=26992204

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002180147A Abandoned CA2180147A1 (fr) 1994-11-16 1995-11-16 Revetements a base d'oxyde de polyethylene reticule destines a ameliorer la compatibilite biologique d'appareils medicaux destines a etre implantes

Country Status (5)

Country Link
EP (1) EP0739218A1 (fr)
JP (1) JPH09507784A (fr)
AU (1) AU4162396A (fr)
CA (1) CA2180147A1 (fr)
WO (1) WO1996014887A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509098B1 (en) * 1995-11-17 2003-01-21 Massachusetts Institute Of Technology Poly(ethylene oxide) coated surfaces
US5830986A (en) * 1996-10-28 1998-11-03 Massachusetts Institute Of Technology Methods for the synthesis of functionalizable poly(ethylene oxide) star macromolecules
WO2003063926A1 (fr) * 2002-02-01 2003-08-07 Sustech Gmbh & Co. Kg Prepolymeres en etoile pour la production de revetements ultraminces formant des hydrogels
US6961610B2 (en) * 2002-04-25 2005-11-01 Medtronic, Inc. Branched polyethylene oxide terminated biomedical polymers and their use in biomedical devices
TW200840554A (en) * 2007-02-28 2008-10-16 Alcon Inc Coated medical implants and lenses
US7790824B2 (en) 2007-07-25 2010-09-07 Alcon, Inc. High refractive index ophthalmic device materials
US9395468B2 (en) * 2012-08-27 2016-07-19 Ocular Dynamics, Llc Contact lens with a hydrophilic layer
JP2017505922A (ja) 2013-11-15 2017-02-23 タンジブル サイエンス リミテッド ライアビリティ カンパニー 親水性層を有するコンタクトレンズ
JP6774947B2 (ja) 2014-12-09 2020-10-28 タンジブル サイエンス インコーポレイテッド 生体適合性層を有する医療デバイスコーティング

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE444950B (sv) * 1984-09-28 1986-05-20 Ytkemiska Inst Ytbelagd artikel, forfarande och medel for framstellning derav samt anvendning derav
JPH0382472A (ja) * 1989-08-28 1991-04-08 Terumo Corp 生体内長期埋植材及びその製造方法
GB9113875D0 (en) * 1991-06-27 1991-08-14 Biointeractions Ltd Polymer coatings
US5375611A (en) * 1993-01-26 1994-12-27 Pharmacia Ab Method for preventing secondary cataract
US5618316A (en) * 1993-12-14 1997-04-08 Hoffman; Allan S. Polyethylene oxide coated intraocular lens

Also Published As

Publication number Publication date
AU4162396A (en) 1996-06-06
JPH09507784A (ja) 1997-08-12
WO1996014887A1 (fr) 1996-05-23
EP0739218A1 (fr) 1996-10-30

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Legal Events

Date Code Title Description
FZDE Dead