CA2175808A1 - Manually-severable coupling device, and medical infusion assembly including same - Google Patents
Manually-severable coupling device, and medical infusion assembly including sameInfo
- Publication number
- CA2175808A1 CA2175808A1 CA002175808A CA2175808A CA2175808A1 CA 2175808 A1 CA2175808 A1 CA 2175808A1 CA 002175808 A CA002175808 A CA 002175808A CA 2175808 A CA2175808 A CA 2175808A CA 2175808 A1 CA2175808 A1 CA 2175808A1
- Authority
- CA
- Canada
- Prior art keywords
- coupling device
- end sections
- tubular end
- tube
- manually
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
- A61M39/221—Frangible or pierceable closures within tubing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
- A61M1/285—Catheters therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/10—Tube connectors; Tube couplings
- A61M2039/1061—Break-apart tubing connectors or couplings
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
A manually-severable coupling device for coupling two tubes, particularly useful in peritoneal dialysis including a flexible plastic member having passageways therethrough and formed with tubular end sections for receiving tubes to be coupled, an annular groove formed intermediate the tubular end sections defining a flexible, weakened, annular web capable of being severed by rotating one of the tubular end sections with respect to the other, and a finger gripping formation integrally formed in each tubular end section on opposite sides of the weakened annular web grippable by a user to rotate the tubular end sections with respect to each other to sever them from each other along the weakened annular web.
Description
wo~s/~7~ 2 i 7 5 ~ 0 8 Pcrm~g~9 ~n~uAhr~y--3Ev~ ~t.~ COVPI.ING l:EVICF, pr~n MED~CP,L ~h~(JS-10~ ASSEMsLY ~NC_UDING S~M~
The ~esent i.nvention ssls~6 to ~ -nv~ sever~ble couplin~ devico ~or c~ pl ~ng ~o tubes. The~ ~nventl~n is pa~oul~rly ~pplic~bl~ in ~uedlca~ ~nfusion a~s~h~ . uch ~s ~re us~d ln perit~n~ d~alysis ~PD), and i; therefo~e.-3r5 belo~ ~ith respQct to euoh ~ pplic~tion. . --- .
Many of ~he ~-~tments use~ ~oday n Qd~C~- ps3ctice invol~e ~using~ solutian~ into thc. pa~cnt a~d~or ~-;~intT~g ~ s ~rom .th~ patie~t . - ~;uch treu ~ ~ s includ~s lnser~in~ an in~ai~c de~icc suc~ as ~ theter or need- e- into th~3 patient, c ~ryil~ out the treatmen~, an~ ~ ving the in~&sive ~ice.
1~ tne eve~t that nl -- o~ such tre~tmen~ are ne~ C~ry, a cath~tcr i~ uscd implant~d, and tne vessel ~r ~ag ~ed for the tre~tment iS r~nr~e~ted to ~nd di~cs~ ctcd f~om the ~ te~
catheter ~owe~er, the numcrou3 mAntpvl~tio~l~ i~volved ~r~tty incr~a~ the danger of ~n~ec~ive agents ente - lng the body at the ~ite of tl~ catheter. Any r~uction, thb~oL~ in the number of ~anlpulatJ ons a~ th~ cathc~cr inlet can ~ expected to lead to a correpo~ g tes.s~ni~g ~f the risk o~ ~nfection .
One of the trea~ments ~- - ly ~d for p~tie~ts sufferlng from Drolon~d renal f~ilure iG Con~ uo~s A~latory ~eritoneal ni:alysi~ (CAPD~. In C~I~, a s~ ile ~alysis so~u~ion i~ infuse~
into the peritone;3 ~ Cav$~y cf t.he. patient Yi;~l an implanted c~theter. ~ollowi ng an aq~Si l; h~tion period of a ~ew hour~, ~uri ng ~hich wa6tc products of l;~e body dl~use into thc solution, ~he was~e-contalning solution is draincd from ~he c~vi~y and a ~resh solutic,n i5 introduced.
W0 9~3/12780 2 1 7 ~ ~ a 8 ~crms9~3~ . .
. .
~ he~a~ove pr.oc~dure is normally perfon~ed ~y-the pati~nt on ~n a~bulator~ ~)9i~, and inuolves ~ mtmber o~ cn~llections an~
alsoonnection~; ~hich :must ~e per~orm~d under ~t~ic~ly a~aptic ~onditions. One of tne ma~or probl~ plagu~ng- pe~i~one~l d~ly~i~ (PD) ~ b thc infecti~n of the perlton~l ca~i~y ~perl~onitls) c~se~ ~y bre~oh~ in the a~optic ~onn~tion procedure These in~ectlons may h~o_ ~ ~eve~e, and ~t ti~es m~y res~lt i~ ~ ~u~al c~f ~he patie.nt from the dlalysis ~C>S~ILc~m~
~ Iany ~nprovements in CAr'D h3~C been i ntroduc~d ov~ ffie years to re~uce che r~sl~ of contr~ct~ng p~ritoniti-~. O.ne of thcsc ~a~: t~a dcv~lopment o~ thF~ " double ba~ " system, . ~ n . wI~ c~
tl ~;;lo~:d sterile ~ in~ludcw bo~ an Qsllpty ~lrainage ~ag and a i~ull solu~on ~ag. ~rhis Yysl,em obviates ~he u~e of eparate ~o~ne~tion tu~ g for ~ac~ of the baS~s, thus re~lv~ t~e ~un~er cf connection~ ~ind ~ n<wt~onC. Wh~ wir-g ~his s~ ..., the nlet ~ort cf the i~uplanted c~ l,he~c ` i3 expo~ed to thc c~n~ri ~r~.~ only ~w~;c~ durin~ one ~c~eatment cy~e~: once when ~
ne~ PD sct i~ co~ cd to thG cathGt~r, as>d once when the set ls . disconnecte~ .
A further deve].opmP~t in t2115 field wa- ~e~:æ;r.~.ly ~es~rl~7ed in U.S. P~ent No~ 5,221,267 to Fol2e~ In tha~ ~y~ , a ~rla~le tub~ ~o~rl ~ng, ~ y br~;:k.~ c in a cn~p ~ ^~ by a hendin~ force, ls ~sit~ one~ ad.~ace~; Lo t~.e end ~ thc PD set which i~ conn~ct~d to the cath~t~r. Follo~l~ infusion of tIle ~;~ril~ solution, the p~ti6nt pcrn~ 3ntly cl ~ , s the .~ubing sect~on interpose~ be~ hç~ c~theter ~s~d the coupling, and thon d~ sconnec~ th~ ln~usion system bY ~ Lll~ cc7upling I ' :
wo g6n~xn 2 i 7 ~ ~ O ~ I ~l/V~9.~39 i , until it - bre~kæ. .-; :;.This r~uc~ t~e - numb~ a~ osures o~ ~he eat~ieter-~y 50~. . Beror~ ths next ~lu~d.:c~ h~ , ~e p. tient~
a~mply di~-nnr~ ts the t~lhtr1~ stt~p frollL the, pre~io~3 ~tchq~l~c ~s~d ~ . .ne._ ~ ~ new ~et .
~lt~ough ti~e :,y:,~. of ~olden d~cr~ ases the r:Ls3~
$nfection, it con~ains a nl-mt-~ of ~t sa<l~ 6.J~:9. The fr~ a~le tu~;~ing must not be too d~fic~lt to brea~c so as- tO ~e sulta}?le ~or~a~ents--$n a weakened cond~tion. On-th~.off~r ~ana, ~f the tu~lng can be broken tDo easily, i~ may break Acc-id~telly l~efore t~e. end of di:~lys~ s is of ~se ~e~y da~g~l.u~, as il~
sucn a case st~rili~cy is ~ p nàcd a~ ~S~QC' ion ~ay r.e~ul~ In addition, ~aggecl ends of the c~ r~ g c~n ~oun~ the pa~e~t, ci rg infection $n that ~a~ . F$n;~_1y, che ~glaity of the couplin~7 Makes it un~ieldy in ~ w of the v ~rious ipulations r~ 5~y d~rlng the di~lys$s l_.c~ ~ ~t.. ;
~ n o~ject of thæ y~e~ inv~l~ion ~s tC pro~S~le a r~nu~ly-severc~le co~lpling de~ricc ha~ing a~h~ æs in the a~ove ~e~;E~cts . Ano~her obJ ect oL the ~ nv~tion i3 to pro~ide .ql infuion assembly includin~ such a co~lrltng devic~.
In ac~rdan~e wi~ch the prescnt i~v~ inn, there i~; p~o~r1ded a manual].y-ç~verable coupling devic,~ ~o:r coupl~ng t~o tub~3, ~OM~ ng a fle~i~le E~ ;tic member h~vln~ ~ y~ ageway t~e~et~ro~g~ and for;ned with plastic end se~--ion~ at its PDoSlce ends for recelviny ~ e tubes to be couplee; an ~ ul~r ~ ylOGv~
~orsned in tl~e. fl~xible Dlastic member intc~ te its ~ u~ulaz end sections dcfining a flexible, we?~kened, ~nn~ r ~e~ cap~ble 0~ be3.ng sev~ y rat~ting thc tu~ula- ~nd section~ with ' .
WO9S~12780 2 1 7 5~3 08 ~ ~3~ ' respect to tlle otAer; an~ a~t nger: ~r1 rPs n~ formation integrally fo~med ln ea:ch of ~he tubular~end sections on oppo~itc s~d~s of the ~e~kened -~nn~ r we~, grlpp~le b~ ;l user to --otatc the tubular end sectlons with ~ L . ta each other to sever tl~
fram.e.a~h. nthe~ alon~. the weaken~ nnular .web ~ 3 ~ill bc dc30sibca morc ..~l9-~l. r}y belo~, . - 8uC~
co~ g d~3vic~ avc~lds t~ ul~ly di;~ Y~ Ld~ descrlbed above, p~ rlsl A~ly when use~ ~ n; a ~ned~l in ~u ion assembly ~or p~rlt~ne~l ~aly~i. q~hu, 'che de~ic~ -ms~. bc -~ttn~he~ to the cathe~er end o~ di~lysis l~ ng~ v~sv~l~y by sJlu~n~J, so that e~mes an ~nteç~ral cn~rl~.ment of t~e dialy~i~ infus~on ~66~rbly. The flDY~h~l~ty of the ~o~r~ 7 dc~ce ~llo~s f~or b~nding ~nd twist~ng to a s~stantial de~r~: without ~i; ~,, thereby im~e1n~ a minimum of int~ferencR aml il~cot)v~."ience dur~g t~ d~alys~ s troatm~nt. In ord~r ~o E;ever thc c~ouplir~g dc-r~cc, the f~ nger gripping form~tio~s ~ (' on t;he o~ite sldes cf ~e we~l~ened ~nm~l ar web a~e ll ~n~ y ç~ripped and ,c,Lated with respect to Qach othQr, ~.g. for more than 90 des~ree~, to scv thc ~nrt~ ~eb. Thi~2 sev~r~ng o~c I ion ls slmple an~l ~equ~res very l~ttle for~ rrh~ e, no 3 agged ends result ~rom t~e s~v~ing According to another ~pect of the inve~tion, there is pruvid~d a medical ln~us~on ;I5S~ y~ lsinçl: a flrst tube for r~nn~c~.tion to an infusion liquid bag for .~upE-l ying an irlfu~ion liquid to a ~ubj~act, a ~:~cond tuba for co~nection to the :~bject to rec~i~rc the infusion li~uidi ~nd ~ ~n~ually-seveLaL~l~
.
' ~ ~0 9Stl278~ 2 1 7 5 8 Q g PcrtUs94n~:
co~r1ing de~rice ~-~ described above con~ecti:~g t:he flrst ~u~e to the secQ~ cube. - - ---~ `u~her ~eatures and ad~ ages of the ~ el.~.ion. will bea~a.anl, from t~ d~_,~pt~on below..
The inve~t~on is hereln ~escri~ed, by ~ay of ex~rl~ only, with referenoe to ~he ;~ c~a ~$ng d~awing ~ wherein:
F~g. 1 ~ ,aLes ~ dou}~le-bag peri~ne~l dialysls (~?D) infus~on assembly constructed ln accordance with the preser~t ln~ tlo~: ~
F~g. 2 iE an cnl;~rged s$de elo~r~t~ riew i~ aLlng the y-severa~le ~upl l ng dev~ce include~i in the assemb~y of FSg. 1:
F~g. 3 $~ a pc.~e.,L~e ~eu of th~ cov~l~ng de~rice of Fig. 2;
Fig. 4 1s a side. el~trationa~ ~view tllus~c.~i~lng t~se coupltng device of F~g~. 2 and 3 .~ftOEr it has ~ v.~lly s~vt:~
~ n~ Fig. ~; is ~ pe~ ve vieW of a annther form of mar~ ly~ ve:L.~.le couE~lin~ de~ice col~L~uct~d in 3ccordance with ~he ~.~.~.L ~ ion.
R~ .~ng to Fig. 1, the~e ls ~ llust~ated a double-bag per1torle.31 ~31alysis (PD) sy~t , g~narally desig~ted 2, inc~.uding a r~ c~l in~u;ion ~ bly, .~nd par~;icular~y a ~n~ l l y-~ever ~ble coupling ~:vice, constr-Cted ln accor~nce ~ith the present ~nven~ion. l'ne illtl~trated ~y~ L~l 2 includes an in~usion li.quid bag ~ cont~ g freh di;~ly ~ute solutlon L~
~e introdvce~ in~o the patient, ~n empty ~lra1naae bag 6 f or rccei~ring th~: wt~te-contalnln~ d~alysa~e ~rom th~o p~ritc~neal .
w0~2780 2 i 7~808 PCr'USg~'l~3g ; -6-. j C~V1~y, ~nd a catheter ~I tA~ -~ po~ 8 ~o~ ~t~-h;ng ~he ~
to the catheter set (not s~own). ~a~ of-t~e bag9 4,6 o~ the ~a ~ ~o~n~oted to ona port o~ 2.,Y-coupling 10 by branch , tubes 12~ al~d ~2b each including c .~v~r~bl~ clQ~p 14n,14b or J orDn1 n5 one of t~e tubes, w~le ~he other is close~. A br~ak-a~ay :~n~ 16 ic ~urthQr in~de~ in.branch tub~ 12b to the d~nage bag 6. 8re~k-~ay c~ l A 16 ~ 3 -e~.~ecti~e ~or~-~lly ~e close tne ~AssAge v~a ~ranc~ tu~e l2b ~o the draina~e b~g 6, ~ut ~ay be w~l ly L~ n away to open thiS pass~e.. -~uch brP~k-~w~y c~n~ s ~re well k~o~n, and ~herefore furthcr dct~ils of its cons~LuCWon are not set Sorth hereln.
ThQ Y-connQctor 10, via its ~-~ 5-1 port 1~, ~nnects the two br~nch tubes 12e,1æb to 8 _ ~ tube 20 uoh that th~ twc branch tubes 12a, ~ ~ay be selectively opened o~ clos~ y ~heir re~pec~ive ~13, 14a,1~b- Tube 20 is in tu~n ~n~-ted, ~ia a ~ ~lly-3e~ ble coupling dcvic~ generally de~ignat~d 2~, to anot~er tube 24, whlc~ i~ in turn con~cted to the c~theter a~achment port 8. The l?,tter ~ube ~4 iurtner ~ncludes a sin~le-; clo3~re cl~mp, i.e. ~ cl3mp (of known c~n6tsuction) which is nor~7y open, n~ ly ~l~s~l>le, and nnn-openable there~fter once it ha~ been m~nt~lly clased. ~u~e 24 ~ e~i n~ tO tne ~ath¢tcr ~tt-s~ t port 8 al~o includes anothQr break-away car~lul~ 28.
. ~ The ~ y-severa~le co~t~l1n~ devlce,cenerally ~iy~la~d 22 in Fig. 1, is ~ore particular~y illllstra~ed in Fi~s. 2 and 3.
It i~ ~ one-piece, f1e~ib1e p1~stic - b~ ha~-ing a through-soi~g PassacTeway 30 and integ~11y ~or~cd with tubu1ar end sectiOns w~? YSIlZ7~0 . . P~ 9~ll243s 2 i 75~Q~
31,32 ~t ~ ~s oppos~ tc es~d3 ~or ~eceiving the ts~o tube3 20, ~4 of tl~e 1nfusion aSSembly ~llus ~L ~ ~,e~l ln ~lg . 1 . E;xamp}es of s:Later~als that could be used for ~nember 22 are soft polyethylene ~d soft - pol~ysop2 1ene. M¢~er 22 i3 furth~r fv_ - ' with ~n ~n~ r y~oc~v~ 33 inte ~di ~t~ t~l~ two t~uL~ul~r e~d . s~ctions 31,32. Groove 33 defin~s a flPxi~le, weak~ed, annl~l2,r web c~p~'ole of belng sev~_ed ~y rotQting o~c o' the end section~
31,32 wltIl respect to ~e other. A ~lnger ~rlpping ~ormztlon 3~, 3~ is fur ther integrally forme~ in eac:~ o the end sectior~s 31,32 osf oppo-~ite ~ide3 of the ~ kened :~nr~ b 33~ gripp~le by a user to rotate ~he end sections wlth re- pect to each o~er in orde~ ~o sever the two ~d ~:eotio~s along the. web 33 In the ~hoA~ nt illu3tr~tcd ir~ Figs. 2 ~nd :~, e~ch flnger grippi~g ~ormatlon 34,35, formed ln the erA sectlons 31,3Z, includes a pair of radially projectin~ ear~ o~ w~ngs, one gea~le by the thum~ ~nd thc othcr by t~c in~ex fin~er of the E~r~on ~;everlng the cs~u~ir~g ~evice. When ~h~ yliny d~v~c~
iC-t~ h~ .vQr~.d, ~ will be descri~ed more partic~ly below, thc~ per3on grip~ the psir of ~ings of one cec~ion ~7ith onc ~3n~, ~nd t~he pair clf wlns~s of the other sectioll W~ he other hand, and then rotates ~ne section with respe.ct to -he other until the coupling dc~oc 22 i~ e~e~ed along the w~rsn~d web -~. Fig.
The ~esent i.nvention ssls~6 to ~ -nv~ sever~ble couplin~ devico ~or c~ pl ~ng ~o tubes. The~ ~nventl~n is pa~oul~rly ~pplic~bl~ in ~uedlca~ ~nfusion a~s~h~ . uch ~s ~re us~d ln perit~n~ d~alysis ~PD), and i; therefo~e.-3r5 belo~ ~ith respQct to euoh ~ pplic~tion. . --- .
Many of ~he ~-~tments use~ ~oday n Qd~C~- ps3ctice invol~e ~using~ solutian~ into thc. pa~cnt a~d~or ~-;~intT~g ~ s ~rom .th~ patie~t . - ~;uch treu ~ ~ s includ~s lnser~in~ an in~ai~c de~icc suc~ as ~ theter or need- e- into th~3 patient, c ~ryil~ out the treatmen~, an~ ~ ving the in~&sive ~ice.
1~ tne eve~t that nl -- o~ such tre~tmen~ are ne~ C~ry, a cath~tcr i~ uscd implant~d, and tne vessel ~r ~ag ~ed for the tre~tment iS r~nr~e~ted to ~nd di~cs~ ctcd f~om the ~ te~
catheter ~owe~er, the numcrou3 mAntpvl~tio~l~ i~volved ~r~tty incr~a~ the danger of ~n~ec~ive agents ente - lng the body at the ~ite of tl~ catheter. Any r~uction, thb~oL~ in the number of ~anlpulatJ ons a~ th~ cathc~cr inlet can ~ expected to lead to a correpo~ g tes.s~ni~g ~f the risk o~ ~nfection .
One of the trea~ments ~- - ly ~d for p~tie~ts sufferlng from Drolon~d renal f~ilure iG Con~ uo~s A~latory ~eritoneal ni:alysi~ (CAPD~. In C~I~, a s~ ile ~alysis so~u~ion i~ infuse~
into the peritone;3 ~ Cav$~y cf t.he. patient Yi;~l an implanted c~theter. ~ollowi ng an aq~Si l; h~tion period of a ~ew hour~, ~uri ng ~hich wa6tc products of l;~e body dl~use into thc solution, ~he was~e-contalning solution is draincd from ~he c~vi~y and a ~resh solutic,n i5 introduced.
W0 9~3/12780 2 1 7 ~ ~ a 8 ~crms9~3~ . .
. .
~ he~a~ove pr.oc~dure is normally perfon~ed ~y-the pati~nt on ~n a~bulator~ ~)9i~, and inuolves ~ mtmber o~ cn~llections an~
alsoonnection~; ~hich :must ~e per~orm~d under ~t~ic~ly a~aptic ~onditions. One of tne ma~or probl~ plagu~ng- pe~i~one~l d~ly~i~ (PD) ~ b thc infecti~n of the perlton~l ca~i~y ~perl~onitls) c~se~ ~y bre~oh~ in the a~optic ~onn~tion procedure These in~ectlons may h~o_ ~ ~eve~e, and ~t ti~es m~y res~lt i~ ~ ~u~al c~f ~he patie.nt from the dlalysis ~C>S~ILc~m~
~ Iany ~nprovements in CAr'D h3~C been i ntroduc~d ov~ ffie years to re~uce che r~sl~ of contr~ct~ng p~ritoniti-~. O.ne of thcsc ~a~: t~a dcv~lopment o~ thF~ " double ba~ " system, . ~ n . wI~ c~
tl ~;;lo~:d sterile ~ in~ludcw bo~ an Qsllpty ~lrainage ~ag and a i~ull solu~on ~ag. ~rhis Yysl,em obviates ~he u~e of eparate ~o~ne~tion tu~ g for ~ac~ of the baS~s, thus re~lv~ t~e ~un~er cf connection~ ~ind ~ n<wt~onC. Wh~ wir-g ~his s~ ..., the nlet ~ort cf the i~uplanted c~ l,he~c ` i3 expo~ed to thc c~n~ri ~r~.~ only ~w~;c~ durin~ one ~c~eatment cy~e~: once when ~
ne~ PD sct i~ co~ cd to thG cathGt~r, as>d once when the set ls . disconnecte~ .
A further deve].opmP~t in t2115 field wa- ~e~:æ;r.~.ly ~es~rl~7ed in U.S. P~ent No~ 5,221,267 to Fol2e~ In tha~ ~y~ , a ~rla~le tub~ ~o~rl ~ng, ~ y br~;:k.~ c in a cn~p ~ ^~ by a hendin~ force, ls ~sit~ one~ ad.~ace~; Lo t~.e end ~ thc PD set which i~ conn~ct~d to the cath~t~r. Follo~l~ infusion of tIle ~;~ril~ solution, the p~ti6nt pcrn~ 3ntly cl ~ , s the .~ubing sect~on interpose~ be~ hç~ c~theter ~s~d the coupling, and thon d~ sconnec~ th~ ln~usion system bY ~ Lll~ cc7upling I ' :
wo g6n~xn 2 i 7 ~ ~ O ~ I ~l/V~9.~39 i , until it - bre~kæ. .-; :;.This r~uc~ t~e - numb~ a~ osures o~ ~he eat~ieter-~y 50~. . Beror~ ths next ~lu~d.:c~ h~ , ~e p. tient~
a~mply di~-nnr~ ts the t~lhtr1~ stt~p frollL the, pre~io~3 ~tchq~l~c ~s~d ~ . .ne._ ~ ~ new ~et .
~lt~ough ti~e :,y:,~. of ~olden d~cr~ ases the r:Ls3~
$nfection, it con~ains a nl-mt-~ of ~t sa<l~ 6.J~:9. The fr~ a~le tu~;~ing must not be too d~fic~lt to brea~c so as- tO ~e sulta}?le ~or~a~ents--$n a weakened cond~tion. On-th~.off~r ~ana, ~f the tu~lng can be broken tDo easily, i~ may break Acc-id~telly l~efore t~e. end of di:~lys~ s is of ~se ~e~y da~g~l.u~, as il~
sucn a case st~rili~cy is ~ p nàcd a~ ~S~QC' ion ~ay r.e~ul~ In addition, ~aggecl ends of the c~ r~ g c~n ~oun~ the pa~e~t, ci rg infection $n that ~a~ . F$n;~_1y, che ~glaity of the couplin~7 Makes it un~ieldy in ~ w of the v ~rious ipulations r~ 5~y d~rlng the di~lys$s l_.c~ ~ ~t.. ;
~ n o~ject of thæ y~e~ inv~l~ion ~s tC pro~S~le a r~nu~ly-severc~le co~lpling de~ricc ha~ing a~h~ æs in the a~ove ~e~;E~cts . Ano~her obJ ect oL the ~ nv~tion i3 to pro~ide .ql infuion assembly includin~ such a co~lrltng devic~.
In ac~rdan~e wi~ch the prescnt i~v~ inn, there i~; p~o~r1ded a manual].y-ç~verable coupling devic,~ ~o:r coupl~ng t~o tub~3, ~OM~ ng a fle~i~le E~ ;tic member h~vln~ ~ y~ ageway t~e~et~ro~g~ and for;ned with plastic end se~--ion~ at its PDoSlce ends for recelviny ~ e tubes to be couplee; an ~ ul~r ~ ylOGv~
~orsned in tl~e. fl~xible Dlastic member intc~ te its ~ u~ulaz end sections dcfining a flexible, we?~kened, ~nn~ r ~e~ cap~ble 0~ be3.ng sev~ y rat~ting thc tu~ula- ~nd section~ with ' .
WO9S~12780 2 1 7 5~3 08 ~ ~3~ ' respect to tlle otAer; an~ a~t nger: ~r1 rPs n~ formation integrally fo~med ln ea:ch of ~he tubular~end sections on oppo~itc s~d~s of the ~e~kened -~nn~ r we~, grlpp~le b~ ;l user to --otatc the tubular end sectlons with ~ L . ta each other to sever tl~
fram.e.a~h. nthe~ alon~. the weaken~ nnular .web ~ 3 ~ill bc dc30sibca morc ..~l9-~l. r}y belo~, . - 8uC~
co~ g d~3vic~ avc~lds t~ ul~ly di;~ Y~ Ld~ descrlbed above, p~ rlsl A~ly when use~ ~ n; a ~ned~l in ~u ion assembly ~or p~rlt~ne~l ~aly~i. q~hu, 'che de~ic~ -ms~. bc -~ttn~he~ to the cathe~er end o~ di~lysis l~ ng~ v~sv~l~y by sJlu~n~J, so that e~mes an ~nteç~ral cn~rl~.ment of t~e dialy~i~ infus~on ~66~rbly. The flDY~h~l~ty of the ~o~r~ 7 dc~ce ~llo~s f~or b~nding ~nd twist~ng to a s~stantial de~r~: without ~i; ~,, thereby im~e1n~ a minimum of int~ferencR aml il~cot)v~."ience dur~g t~ d~alys~ s troatm~nt. In ord~r ~o E;ever thc c~ouplir~g dc-r~cc, the f~ nger gripping form~tio~s ~ (' on t;he o~ite sldes cf ~e we~l~ened ~nm~l ar web a~e ll ~n~ y ç~ripped and ,c,Lated with respect to Qach othQr, ~.g. for more than 90 des~ree~, to scv thc ~nrt~ ~eb. Thi~2 sev~r~ng o~c I ion ls slmple an~l ~equ~res very l~ttle for~ rrh~ e, no 3 agged ends result ~rom t~e s~v~ing According to another ~pect of the inve~tion, there is pruvid~d a medical ln~us~on ;I5S~ y~ lsinçl: a flrst tube for r~nn~c~.tion to an infusion liquid bag for .~upE-l ying an irlfu~ion liquid to a ~ubj~act, a ~:~cond tuba for co~nection to the :~bject to rec~i~rc the infusion li~uidi ~nd ~ ~n~ually-seveLaL~l~
.
' ~ ~0 9Stl278~ 2 1 7 5 8 Q g PcrtUs94n~:
co~r1ing de~rice ~-~ described above con~ecti:~g t:he flrst ~u~e to the secQ~ cube. - - ---~ `u~her ~eatures and ad~ ages of the ~ el.~.ion. will bea~a.anl, from t~ d~_,~pt~on below..
The inve~t~on is hereln ~escri~ed, by ~ay of ex~rl~ only, with referenoe to ~he ;~ c~a ~$ng d~awing ~ wherein:
F~g. 1 ~ ,aLes ~ dou}~le-bag peri~ne~l dialysls (~?D) infus~on assembly constructed ln accordance with the preser~t ln~ tlo~: ~
F~g. 2 iE an cnl;~rged s$de elo~r~t~ riew i~ aLlng the y-severa~le ~upl l ng dev~ce include~i in the assemb~y of FSg. 1:
F~g. 3 $~ a pc.~e.,L~e ~eu of th~ cov~l~ng de~rice of Fig. 2;
Fig. 4 1s a side. el~trationa~ ~view tllus~c.~i~lng t~se coupltng device of F~g~. 2 and 3 .~ftOEr it has ~ v.~lly s~vt:~
~ n~ Fig. ~; is ~ pe~ ve vieW of a annther form of mar~ ly~ ve:L.~.le couE~lin~ de~ice col~L~uct~d in 3ccordance with ~he ~.~.~.L ~ ion.
R~ .~ng to Fig. 1, the~e ls ~ llust~ated a double-bag per1torle.31 ~31alysis (PD) sy~t , g~narally desig~ted 2, inc~.uding a r~ c~l in~u;ion ~ bly, .~nd par~;icular~y a ~n~ l l y-~ever ~ble coupling ~:vice, constr-Cted ln accor~nce ~ith the present ~nven~ion. l'ne illtl~trated ~y~ L~l 2 includes an in~usion li.quid bag ~ cont~ g freh di;~ly ~ute solutlon L~
~e introdvce~ in~o the patient, ~n empty ~lra1naae bag 6 f or rccei~ring th~: wt~te-contalnln~ d~alysa~e ~rom th~o p~ritc~neal .
w0~2780 2 i 7~808 PCr'USg~'l~3g ; -6-. j C~V1~y, ~nd a catheter ~I tA~ -~ po~ 8 ~o~ ~t~-h;ng ~he ~
to the catheter set (not s~own). ~a~ of-t~e bag9 4,6 o~ the ~a ~ ~o~n~oted to ona port o~ 2.,Y-coupling 10 by branch , tubes 12~ al~d ~2b each including c .~v~r~bl~ clQ~p 14n,14b or J orDn1 n5 one of t~e tubes, w~le ~he other is close~. A br~ak-a~ay :~n~ 16 ic ~urthQr in~de~ in.branch tub~ 12b to the d~nage bag 6. 8re~k-~ay c~ l A 16 ~ 3 -e~.~ecti~e ~or~-~lly ~e close tne ~AssAge v~a ~ranc~ tu~e l2b ~o the draina~e b~g 6, ~ut ~ay be w~l ly L~ n away to open thiS pass~e.. -~uch brP~k-~w~y c~n~ s ~re well k~o~n, and ~herefore furthcr dct~ils of its cons~LuCWon are not set Sorth hereln.
ThQ Y-connQctor 10, via its ~-~ 5-1 port 1~, ~nnects the two br~nch tubes 12e,1æb to 8 _ ~ tube 20 uoh that th~ twc branch tubes 12a, ~ ~ay be selectively opened o~ clos~ y ~heir re~pec~ive ~13, 14a,1~b- Tube 20 is in tu~n ~n~-ted, ~ia a ~ ~lly-3e~ ble coupling dcvic~ generally de~ignat~d 2~, to anot~er tube 24, whlc~ i~ in turn con~cted to the c~theter a~achment port 8. The l?,tter ~ube ~4 iurtner ~ncludes a sin~le-; clo3~re cl~mp, i.e. ~ cl3mp (of known c~n6tsuction) which is nor~7y open, n~ ly ~l~s~l>le, and nnn-openable there~fter once it ha~ been m~nt~lly clased. ~u~e 24 ~ e~i n~ tO tne ~ath¢tcr ~tt-s~ t port 8 al~o includes anothQr break-away car~lul~ 28.
. ~ The ~ y-severa~le co~t~l1n~ devlce,cenerally ~iy~la~d 22 in Fig. 1, is ~ore particular~y illllstra~ed in Fi~s. 2 and 3.
It i~ ~ one-piece, f1e~ib1e p1~stic - b~ ha~-ing a through-soi~g PassacTeway 30 and integ~11y ~or~cd with tubu1ar end sectiOns w~? YSIlZ7~0 . . P~ 9~ll243s 2 i 75~Q~
31,32 ~t ~ ~s oppos~ tc es~d3 ~or ~eceiving the ts~o tube3 20, ~4 of tl~e 1nfusion aSSembly ~llus ~L ~ ~,e~l ln ~lg . 1 . E;xamp}es of s:Later~als that could be used for ~nember 22 are soft polyethylene ~d soft - pol~ysop2 1ene. M¢~er 22 i3 furth~r fv_ - ' with ~n ~n~ r y~oc~v~ 33 inte ~di ~t~ t~l~ two t~uL~ul~r e~d . s~ctions 31,32. Groove 33 defin~s a flPxi~le, weak~ed, annl~l2,r web c~p~'ole of belng sev~_ed ~y rotQting o~c o' the end section~
31,32 wltIl respect to ~e other. A ~lnger ~rlpping ~ormztlon 3~, 3~ is fur ther integrally forme~ in eac:~ o the end sectior~s 31,32 osf oppo-~ite ~ide3 of the ~ kened :~nr~ b 33~ gripp~le by a user to rotate ~he end sections wlth re- pect to each o~er in orde~ ~o sever the two ~d ~:eotio~s along the. web 33 In the ~hoA~ nt illu3tr~tcd ir~ Figs. 2 ~nd :~, e~ch flnger grippi~g ~ormatlon 34,35, formed ln the erA sectlons 31,3Z, includes a pair of radially projectin~ ear~ o~ w~ngs, one gea~le by the thum~ ~nd thc othcr by t~c in~ex fin~er of the E~r~on ~;everlng the cs~u~ir~g ~evice. When ~h~ yliny d~v~c~
iC-t~ h~ .vQr~.d, ~ will be descri~ed more partic~ly below, thc~ per3on grip~ the psir of ~ings of one cec~ion ~7ith onc ~3n~, ~nd t~he pair clf wlns~s of the other sectioll W~ he other hand, and then rotates ~ne section with respe.ct to -he other until the coupling dc~oc 22 i~ e~e~ed along the w~rsn~d web -~. Fig.
4 illustrates ~he coupling device when so severed.
Follow~n~ i s a descrl~tlon o~ one r~nn~r of usin~ the system illustratQd in Fig. 1 ~or periton~al dialysis (PD) of a patiQnt having ~ c~theter set $mplantcd in the patient ' s peri~oneal ~;avlty. It will De assume~ tnat tne perltoncal cavl~y had ~een W095fl2780 2 i 7 ~ ~ O ~ P~/[IS4~I~39 . . ~retriously filled with a dialy~a~e ~olution where ~t h~s re ~ e~
~or a suffioic~t time to rcceive by diffu~ n the waste ~oducts of- the ~o~ly, ~nd now ~t $s ready ~o drain the waste-cont~ .,g solution from th~ peritoneal cavity and -o int~oduce ~ l~resh colution.
~ he PD set illuc;tr~ted ln ~15~. 1, ir~Cll ~in~J a fresh solut~on bag 4, an empty dr~i nage ~ag 6, and the tubin~ b~ y cort~ nc~ the D~nu;~1 ly-3ever~ble couplillg deYlce 22, ~s cor~ c1,ed to t~le patlent ~ s cath~ter se- t~i a the cath~t~r ~tt~ T~,ent ~ort 8. Th~. single-~losu~Q cla~p 26 i8 open, ~nd the two cl~, c 14a,1~b in thc br~nc~-e~ 12 ,12b to the solut~on bag 4 ;md drain~ge ~ag 6, r~ ;~ectlvely, are c}osed.
The two break-away r-~nn~Tla~ 28 2~d 16 ~irQ then broken a~yi the drainage bag 6 i louercd ~elo~ the ; ~tient '~- perltonc~l c~ity; and cl~mp l~b ~n ~r~i~ch 12b ls oper~ . T~is perm~ts the dialyxate conr~ining ~:he waste m~terials tc be grav~ fcd ~rom ~h~ perltone~l cavity into the dr3ina~e ~ag 6 ~ia a 1~; t~c~men~
por~ ~, opcn clamF 26, couplln~ ce Z~ an~ brancn 12h of Y--~or~n~c:~:ur 1~.
On ~ompletion o the drain3g¢, clamp 14b is clo~èd; the ~;olution bag 4 is r~ised above the Perltonea} cavity, and c~lamp 14~ i~ ~ ch 12a to tne solutlon bag ~ i~ opened ~i~ allo~
the fresh ~ialy~te. solution to flo~ by gravity from b~g 4 into t~he peritono~l catrity ~'i2 ~r~nch 12tl, Y-coupling 10, co~pling ~evice 22, opcn claMp 26 ~d ;~tt~chlnen~ po~t 8.
. When the solution bag has ~m~ti.ed, the singl~-clo~ure cl~mp 26 is n~w closed A~ indicated carlicr, once this ~ lnp is .
' W09*127~ 2 i 75~ 08 P~U~94r12~39:
.
_g_ closed, it: can no longer b~ reopened. Accordin~ly, th~
pesito~c~3l cavity is now ~ermanently di s~o~ ected rom either solu~io~l ~ag 4 or t~le dr:~inag~ bag 6 These. two ~ s, toge~;ner ~lth the port~on o~ the tublng ~s~ ly ~nn~t ~ th~am to l,ng dev~.co 22, may therefore be remo~e~ by ~31 1 y severing the coupling de~rice 22. 9~hi~ i~ do~e ~y placing the index f~n~er ~nd thum~ of one hand o~l the oppos~te aidea of th~3 ~wo ~ing~ 3A
on ~n~ ci~ of the wealcened web 33, and pl ;~o~ lg the index f nge~
~d thun~ of the other h~nd orl opposite si~ec of the wings 35 on th~ o'cher s1 de Of web 33, and then rot~ting thc two wing~ with rc3pcot to each other until t~e C~UDl i n~a dev_ce 22 severs .~long t~-~ w~ 33. The ~reb i6 pr~rably of ~1 --hi Pcc a~d of a material such ~a C it will te~r upon rot~ting the two tu~e rection~ 31,32, i:n~e~rally formea wlth ~he _wo wings 34,3~, ~n anyular ~ ~u..l, of mo~e than 9~ om g~ t)~ se~,3--c~
of the p~ ty o~ ~is materi~ sev~ring actios~ can be perfo~racd wit~ ~ery li~le exer~ion and ~luires no special ~mplements such ~ ~ 30;~60~ or }cnife, Th~. torn e~es of ~ne so-sev~:~ ea tube sectlonc; 31, 32 cre not d;mgc~rou~ b~cau~Q o the ~oftn~s~ ar~d flexihility of tne plastic IlU~ ;er~al of whi~h the co~lpling detrice 22 i~ made.
Since nl~e 24 ;~dj~cent to the cath~tcr ~t i~ mr~d cl~cec~
~y th~ single-c.l ~;ure clamp 26, dlscon~leC;t_ng the uscd ~ ~et ~ron~ the paticn~ in th~ ~ove-describ~A ~anr er does not t nvolve exposure vf tl~ peritoneal cq~ity to po~ le lnfecti~n The r~:idual port1 on of ~he PD ~e ~; rem~ining ~tt ~ched to ~he pa~i~nt iF rc~lativ~ly short and ~ ~; also flexl~le ~o that ~ lo~s not v~o~o ,~ 1 7 i, g ~ q~39 int.erfere witn the ~at~ent!s ~ LY;ties du~ing ~he dwel~ ~imc o~
thc dialy~at~ in the- peri'r:oneal cavlty.
At the end of the dwell period, t~e catheter attachmen~
port 8 is detAche~ from the catheter ~c~ ( for e~mr~ Ç' ~Y
~ J~_ e~3ng), and a nQw PD çe~ can then ~e at-ach~. Thls ls the o~y I ime during the di21y~ cycl~ when t}~e cavity is ex~o!;e.d to ;the environmen'C..
~ Fig 5 illu.~ tes a varia~ion ~ ~he const~c~on of the COt~ ; ng device 22-. - In th$s variation, -he. ~inger-~rippln5;
formation lntegrally forn~ed in tubular e~e~siGn 41 on one ~;ide of t~ n~ web 43 al~o inClUdes a pair o~ rad~ y pro~:c~ g wings, as ~hown ~t 44 in Fig. 5. However, the fin~er-grippir~
formatlon o~ the otller 'cv~vl~r cnd ~ect~on ~2 i5 i~ ~h~ ro~m o~
a plurality o~ ~xiAl~y-extend1rlg cl~nf~nt~ally-sp~c~d ril:s 45 h~ving 3n oi~ter effc~ctive diam~ter substa-ltially croll~?- tnan that ~f the p~ir o~ radi~lly-projectir~g wing ~. Th~ tiu~ular end sect;c~n ~2 formecl w~th the s~aller~ e~er- ribs 4S ~ould recei~e tubc 24 which ror~ j ns attached t~ -~e patient w~ien the . ln~ler of 1;h~ system has been ~e.~er6d as deLcrib~d a~ove, ~nd the.refore would e~en furt~er decrease 1;l~ possi3;le intererenc~
or i~co~Yc~i~r~c~ to the s~ e.ct by re~i r i ~ tl~s res~ au 1 part o~ he set att~ hed to the patient during the dialys~ dwell per~oc~. ; -Many other variat.;~n~, modi~ica~ionS and appllcati~ the in~rcntion wil I ~ 3pparent . ~ ' , ' .
Follow~n~ i s a descrl~tlon o~ one r~nn~r of usin~ the system illustratQd in Fig. 1 ~or periton~al dialysis (PD) of a patiQnt having ~ c~theter set $mplantcd in the patient ' s peri~oneal ~;avlty. It will De assume~ tnat tne perltoncal cavl~y had ~een W095fl2780 2 i 7 ~ ~ O ~ P~/[IS4~I~39 . . ~retriously filled with a dialy~a~e ~olution where ~t h~s re ~ e~
~or a suffioic~t time to rcceive by diffu~ n the waste ~oducts of- the ~o~ly, ~nd now ~t $s ready ~o drain the waste-cont~ .,g solution from th~ peritoneal cavity and -o int~oduce ~ l~resh colution.
~ he PD set illuc;tr~ted ln ~15~. 1, ir~Cll ~in~J a fresh solut~on bag 4, an empty dr~i nage ~ag 6, and the tubin~ b~ y cort~ nc~ the D~nu;~1 ly-3ever~ble couplillg deYlce 22, ~s cor~ c1,ed to t~le patlent ~ s cath~ter se- t~i a the cath~t~r ~tt~ T~,ent ~ort 8. Th~. single-~losu~Q cla~p 26 i8 open, ~nd the two cl~, c 14a,1~b in thc br~nc~-e~ 12 ,12b to the solut~on bag 4 ;md drain~ge ~ag 6, r~ ;~ectlvely, are c}osed.
The two break-away r-~nn~Tla~ 28 2~d 16 ~irQ then broken a~yi the drainage bag 6 i louercd ~elo~ the ; ~tient '~- perltonc~l c~ity; and cl~mp l~b ~n ~r~i~ch 12b ls oper~ . T~is perm~ts the dialyxate conr~ining ~:he waste m~terials tc be grav~ fcd ~rom ~h~ perltone~l cavity into the dr3ina~e ~ag 6 ~ia a 1~; t~c~men~
por~ ~, opcn clamF 26, couplln~ ce Z~ an~ brancn 12h of Y--~or~n~c:~:ur 1~.
On ~ompletion o the drain3g¢, clamp 14b is clo~èd; the ~;olution bag 4 is r~ised above the Perltonea} cavity, and c~lamp 14~ i~ ~ ch 12a to tne solutlon bag ~ i~ opened ~i~ allo~
the fresh ~ialy~te. solution to flo~ by gravity from b~g 4 into t~he peritono~l catrity ~'i2 ~r~nch 12tl, Y-coupling 10, co~pling ~evice 22, opcn claMp 26 ~d ;~tt~chlnen~ po~t 8.
. When the solution bag has ~m~ti.ed, the singl~-clo~ure cl~mp 26 is n~w closed A~ indicated carlicr, once this ~ lnp is .
' W09*127~ 2 i 75~ 08 P~U~94r12~39:
.
_g_ closed, it: can no longer b~ reopened. Accordin~ly, th~
pesito~c~3l cavity is now ~ermanently di s~o~ ected rom either solu~io~l ~ag 4 or t~le dr:~inag~ bag 6 These. two ~ s, toge~;ner ~lth the port~on o~ the tublng ~s~ ly ~nn~t ~ th~am to l,ng dev~.co 22, may therefore be remo~e~ by ~31 1 y severing the coupling de~rice 22. 9~hi~ i~ do~e ~y placing the index f~n~er ~nd thum~ of one hand o~l the oppos~te aidea of th~3 ~wo ~ing~ 3A
on ~n~ ci~ of the wealcened web 33, and pl ;~o~ lg the index f nge~
~d thun~ of the other h~nd orl opposite si~ec of the wings 35 on th~ o'cher s1 de Of web 33, and then rot~ting thc two wing~ with rc3pcot to each other until t~e C~UDl i n~a dev_ce 22 severs .~long t~-~ w~ 33. The ~reb i6 pr~rably of ~1 --hi Pcc a~d of a material such ~a C it will te~r upon rot~ting the two tu~e rection~ 31,32, i:n~e~rally formea wlth ~he _wo wings 34,3~, ~n anyular ~ ~u..l, of mo~e than 9~ om g~ t)~ se~,3--c~
of the p~ ty o~ ~is materi~ sev~ring actios~ can be perfo~racd wit~ ~ery li~le exer~ion and ~luires no special ~mplements such ~ ~ 30;~60~ or }cnife, Th~. torn e~es of ~ne so-sev~:~ ea tube sectlonc; 31, 32 cre not d;mgc~rou~ b~cau~Q o the ~oftn~s~ ar~d flexihility of tne plastic IlU~ ;er~al of whi~h the co~lpling detrice 22 i~ made.
Since nl~e 24 ;~dj~cent to the cath~tcr ~t i~ mr~d cl~cec~
~y th~ single-c.l ~;ure clamp 26, dlscon~leC;t_ng the uscd ~ ~et ~ron~ the paticn~ in th~ ~ove-describ~A ~anr er does not t nvolve exposure vf tl~ peritoneal cq~ity to po~ le lnfecti~n The r~:idual port1 on of ~he PD ~e ~; rem~ining ~tt ~ched to ~he pa~i~nt iF rc~lativ~ly short and ~ ~; also flexl~le ~o that ~ lo~s not v~o~o ,~ 1 7 i, g ~ q~39 int.erfere witn the ~at~ent!s ~ LY;ties du~ing ~he dwel~ ~imc o~
thc dialy~at~ in the- peri'r:oneal cavlty.
At the end of the dwell period, t~e catheter attachmen~
port 8 is detAche~ from the catheter ~c~ ( for e~mr~ Ç' ~Y
~ J~_ e~3ng), and a nQw PD çe~ can then ~e at-ach~. Thls ls the o~y I ime during the di21y~ cycl~ when t}~e cavity is ex~o!;e.d to ;the environmen'C..
~ Fig 5 illu.~ tes a varia~ion ~ ~he const~c~on of the COt~ ; ng device 22-. - In th$s variation, -he. ~inger-~rippln5;
formation lntegrally forn~ed in tubular e~e~siGn 41 on one ~;ide of t~ n~ web 43 al~o inClUdes a pair o~ rad~ y pro~:c~ g wings, as ~hown ~t 44 in Fig. 5. However, the fin~er-grippir~
formatlon o~ the otller 'cv~vl~r cnd ~ect~on ~2 i5 i~ ~h~ ro~m o~
a plurality o~ ~xiAl~y-extend1rlg cl~nf~nt~ally-sp~c~d ril:s 45 h~ving 3n oi~ter effc~ctive diam~ter substa-ltially croll~?- tnan that ~f the p~ir o~ radi~lly-projectir~g wing ~. Th~ tiu~ular end sect;c~n ~2 formecl w~th the s~aller~ e~er- ribs 4S ~ould recei~e tubc 24 which ror~ j ns attached t~ -~e patient w~ien the . ln~ler of 1;h~ system has been ~e.~er6d as deLcrib~d a~ove, ~nd the.refore would e~en furt~er decrease 1;l~ possi3;le intererenc~
or i~co~Yc~i~r~c~ to the s~ e.ct by re~i r i ~ tl~s res~ au 1 part o~ he set att~ hed to the patient during the dialys~ dwell per~oc~. ; -Many other variat.;~n~, modi~ica~ionS and appllcati~ the in~rcntion wil I ~ 3pparent . ~ ' , ' .
Claims (10)
AND MEDICAL INFUSION ASSEMBLY INCLUDING SAME
1. A manually-severable coupling device for coupling two tubes, comprising:
a flexible plastic member having a passageway therethrough and formed with tubular end sections at its opposite ends for receiving the tubes to be coupled;an annular groove formed in said flexible plastic member intermediate its tubular end sections defining a flexible, weakened, annular web capable of beingsevered by rotating one of said tubular end sections with respect to the other;
and a finger gripping formation integrally formed in each of said tubular end sections on opposite sides of said weakened annular web, grippable by a user to rotate said tubular end sections with respect to each other to sever them from each other along said weakened annular web.
a flexible plastic member having a passageway therethrough and formed with tubular end sections at its opposite ends for receiving the tubes to be coupled;an annular groove formed in said flexible plastic member intermediate its tubular end sections defining a flexible, weakened, annular web capable of beingsevered by rotating one of said tubular end sections with respect to the other;
and a finger gripping formation integrally formed in each of said tubular end sections on opposite sides of said weakened annular web, grippable by a user to rotate said tubular end sections with respect to each other to sever them from each other along said weakened annular web.
2. The coupling device according to claim 1, wherein said finger gripping formation integrally formed in at least one of said tubular end sections includes a pair of radially projecting wings engageable by the thumb and index finger, respectively, of a person severing the coupling device by rotating said end sections.
3. The coupling device according to claim 1, wherein said finger gripping formation integrally formed in both of said tubular end sections includes a pair of radially projecting wings engageable by the thumb and index finger, respectively, of a person severing the coupling device by rotating said end sections.
4. The coupling device according to claim 1, wherein said finger gripping formation integrally formed in at least one of said tubular end sections includes a plurality of axially-extending circumferentially-spaced ribs engageable by the thumb and index finger, respectively, of a person severing the coupling device by rotating said end sections.
5. The coupling device according to claim 1, wherein said finger gripping formation integrally formed in one of said tubular end sections includes a pair of radially-projecting wings engageable by the thumb and index finger, respectively, of one hand of a person severing the coupling device; and the finger gripping formation integrally formed in the other of said tubular end sections includes a plurality of axially-extending circumferentially-spaced ribs engageable by the thumb and index finger, respectively, of the other hand of the person severing the coupling device; said plurality of radially-extending circumferentially-spaced ribs having an outer effective diameter substantially smaller than that of said pair of radially-projecting wings.
6. A medical infusion assembly particularly useful for peritoneal dialysis, comprising:
a first tube for connection to an infusion liquid bag for supplying an infusion liquid to a subject;
a second tube for connection to the subject to receive the infusion liquid;
and a manually-severable coupling device according to claim 1 connecting said first tube to said second tube.
a first tube for connection to an infusion liquid bag for supplying an infusion liquid to a subject;
a second tube for connection to the subject to receive the infusion liquid;
and a manually-severable coupling device according to claim 1 connecting said first tube to said second tube.
7. The medical infusion assembly according to claim 6, wherein said first tube includes one branch connectable to said infusion liquid bag, a second branch connectable to a liquid drainage bag for draining a liquid, and a clamp in each of said branches to selectively open either of said first or second branches while the other is closed.
8. The medical infusion assembly according to claim 7, wherein said second tube includes a valve which is normally opened, manually closable, and non-openable once it has been manually closed.
9. The medical infusion assembly to claim 7, wherein, in the manually-severable coupling device, said finger gripping formation connected to said first tube includes a pair of radially-projecting wings engageable by the thumb and index finger, respectively, of one hand of a person severing the coupling device; and the finger-gripping formation integrally formed in the tubular end section connected to said second tube includes a plurality of axially-extending circumferentially-spaced ribs engageable by the thumb and index finger, respectively, of the other hand of the person severing the coupling device; said axially-extending circumferentially-spaced ribs having an outer effective diameter substantially smaller than that of said pair of radially-projecting wings.
10. The medical infusion assembly according to claim 7, wherein said first tube is connected to said first and second branches by a Y-connector, wherein said second branch of the first tube includes a break-away cannula, and wherein said second tube also includes a break-away cannula.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL107509A IL107509A (en) | 1993-11-05 | 1993-11-05 | Coupling device |
| IL107,509 | 1993-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2175808A1 true CA2175808A1 (en) | 1995-05-11 |
Family
ID=11065417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002175808A Abandoned CA2175808A1 (en) | 1993-11-05 | 1994-10-28 | Manually-severable coupling device, and medical infusion assembly including same |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0728274A4 (en) |
| CA (1) | CA2175808A1 (en) |
| IL (1) | IL107509A (en) |
| WO (1) | WO1995012780A1 (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2420286A1 (en) | 2010-08-18 | 2012-02-22 | Fresenius Kabi Deutschland GmbH | Method and device for sterile connection of hoses |
| US9533135B2 (en) | 2014-06-19 | 2017-01-03 | Fenwal, Inc. | Method for forming, opening and/or evaluating a connection site |
| US10919235B2 (en) | 2017-06-07 | 2021-02-16 | Fenwal, Inc. | Apparatus and method for mechanically opening a connection site |
| US20220387774A1 (en) * | 2021-06-03 | 2022-12-08 | Fresenius Medical Care Holdings, Inc. | Medical Fluid Line Connection Devices |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE511483A (en) * | ||||
| US3342179A (en) * | 1965-06-18 | 1967-09-19 | Abbott Lab | Blood collection and sampling apparatus having separable coupling means |
| JPS61113467A (en) * | 1984-11-06 | 1986-05-31 | テルモ株式会社 | Medical appliances |
| JPS63230177A (en) * | 1987-03-19 | 1988-09-26 | テルモ株式会社 | Tube body openable by breakage |
| US4899903A (en) * | 1988-06-27 | 1990-02-13 | Terumo Kabushiki Kaisha | Tube assembly provided with a breakaway plug |
| US5221267A (en) * | 1990-11-30 | 1993-06-22 | Fresenius Usa, Inc. | Breakable tubing coupling |
| US5259843A (en) * | 1991-11-14 | 1993-11-09 | Kawasumi Laboratories Inc. | Medical connector for attaching to liquid introducing tube |
-
1993
- 1993-11-05 IL IL107509A patent/IL107509A/en not_active IP Right Cessation
-
1994
- 1994-10-28 EP EP95900475A patent/EP0728274A4/en not_active Withdrawn
- 1994-10-28 CA CA002175808A patent/CA2175808A1/en not_active Abandoned
- 1994-10-28 WO PCT/US1994/012439 patent/WO1995012780A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0728274A4 (en) | 1997-06-04 |
| IL107509A (en) | 1998-02-22 |
| EP0728274A1 (en) | 1996-08-28 |
| IL107509A0 (en) | 1994-02-27 |
| WO1995012780A1 (en) | 1995-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |