CA2172053A1 - Process (i) for the preparation of powdered medicament - Google Patents

Process (i) for the preparation of powdered medicament

Info

Publication number
CA2172053A1
CA2172053A1 CA002172053A CA2172053A CA2172053A1 CA 2172053 A1 CA2172053 A1 CA 2172053A1 CA 002172053 A CA002172053 A CA 002172053A CA 2172053 A CA2172053 A CA 2172053A CA 2172053 A1 CA2172053 A1 CA 2172053A1
Authority
CA
Canada
Prior art keywords
agglomerates
finely divided
screw feeder
powdered medicament
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002172053A
Other languages
French (fr)
Other versions
CA2172053C (en
Inventor
Eva Trofast
Johan Falk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303214A external-priority patent/SE9303214D0/en
Priority claimed from SE9304271A external-priority patent/SE9304271D0/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/SE1994/000896 external-priority patent/WO1995009615A1/en
Publication of CA2172053A1 publication Critical patent/CA2172053A1/en
Application granted granted Critical
Publication of CA2172053C publication Critical patent/CA2172053C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)

Abstract

According to the invention there is provided a method of treatment of a finely divided powdered medicament having a particle size smaller than 10 µm and poor flowing properties to form, in a controlled manner, agglomerates or pellets which are free flowing and which are capable of breaking down to provide the finely divided medicament, comprising the steps of agglomeration of the finely divided powdered medicament by feeding the material to a screw feeder, letting the material pass through the screw feeder thereby obtaining agglomerates, spheronizing the resulting agglomerates in order to obtain agglomerates which are more spherical, more dense and more compact than the agglomerates obtained from the agglomeration process in the screw feeder, and sizing the agglomerates to obtain a uniform size of the final product. According to the invention there is also provided an apparatus for carrying out the method.
CA002172053A 1993-10-01 1994-09-29 Process (i) for the preparation of powdered medicament Expired - Lifetime CA2172053C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
SE9303214-2 1993-10-01
SE9303214A SE9303214D0 (en) 1993-10-01 1993-10-01 Process I
SE9304271-1 1993-12-22
SE9304271A SE9304271D0 (en) 1993-12-22 1993-12-22 Process I
PCT/SE1994/000896 WO1995009615A1 (en) 1993-10-01 1994-09-29 Process i

Publications (2)

Publication Number Publication Date
CA2172053A1 true CA2172053A1 (en) 1995-04-13
CA2172053C CA2172053C (en) 2005-12-06

Family

ID=29272468

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002172053A Expired - Lifetime CA2172053C (en) 1993-10-01 1994-09-29 Process (i) for the preparation of powdered medicament

Country Status (6)

Country Link
KR (1) KR100347496B1 (en)
CA (1) CA2172053C (en)
IS (1) IS1873B (en)
PH (1) PH30858A (en)
TW (1) TW283640B (en)
UA (1) UA41373C2 (en)

Also Published As

Publication number Publication date
TW283640B (en) 1996-08-21
CA2172053C (en) 2005-12-06
UA41373C2 (en) 2001-09-17
KR100347496B1 (en) 2002-12-26
IS1873B (en) 2003-05-20
IS4215A (en) 1995-04-02
PH30858A (en) 1997-12-09

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Effective date: 20140929