CA2166479C - Nouvelles tyrosine phosphatases a densite renforcee - Google Patents

Nouvelles tyrosine phosphatases a densite renforcee Download PDF

Info

Publication number
CA2166479C
CA2166479C CA002166479A CA2166479A CA2166479C CA 2166479 C CA2166479 C CA 2166479C CA 002166479 A CA002166479 A CA 002166479A CA 2166479 A CA2166479 A CA 2166479A CA 2166479 C CA2166479 C CA 2166479C
Authority
CA
Canada
Prior art keywords
protein
binding
type iii
dna
protein tyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002166479A
Other languages
English (en)
Other versions
CA2166479A1 (fr
Inventor
Nicholas K. Tonks
Arnie Ostman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cold Spring Harbor Laboratory
Original Assignee
Cold Spring Harbor Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Laboratory filed Critical Cold Spring Harbor Laboratory
Priority to CA002537374A priority Critical patent/CA2537374A1/fr
Priority claimed from PCT/US1995/005512 external-priority patent/WO1995030008A1/fr
Publication of CA2166479A1 publication Critical patent/CA2166479A1/fr
Application granted granted Critical
Publication of CA2166479C publication Critical patent/CA2166479C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention porte sur de nouvelles tyrosine phosphatases de type III à densité renforcée dont l'enzyme humaine DEP-1 est un exemple. L'invention porte également sur des polynucléotides codant pour la DEP-1 humaine et sur des méthodes et matériaux servant à la reproduire par recombinaison. Elle porte en outre sur des molécules fixatrices spécifiques à la DEP-1 et servant à en moduler les activités biologiques.
CA002166479A 1994-05-03 1995-05-03 Nouvelles tyrosine phosphatases a densite renforcee Expired - Lifetime CA2166479C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002537374A CA2537374A1 (fr) 1994-05-03 1995-05-03 Nouvelles tyrosine phosphatases a densite renforcee

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23794094A 1994-05-03 1994-05-03
US08/237,940 1994-05-03
PCT/US1995/005512 WO1995030008A1 (fr) 1994-05-03 1995-05-03 Nouvelles tyrosine phosphatases a densite renforcee

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA002537374A Division CA2537374A1 (fr) 1994-05-03 1995-05-03 Nouvelles tyrosine phosphatases a densite renforcee

Publications (2)

Publication Number Publication Date
CA2166479A1 CA2166479A1 (fr) 1995-11-09
CA2166479C true CA2166479C (fr) 2007-02-06

Family

ID=37734812

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002166479A Expired - Lifetime CA2166479C (fr) 1994-05-03 1995-05-03 Nouvelles tyrosine phosphatases a densite renforcee

Country Status (1)

Country Link
CA (1) CA2166479C (fr)

Also Published As

Publication number Publication date
CA2166479A1 (fr) 1995-11-09

Similar Documents

Publication Publication Date Title
US5702936A (en) Cyclic GMP-binding, cyclic GMP-specific phosphodiesterase materials and methods
Desai et al. The catalytic activity of the CD45 membrane‐proximal phosphatase domain is required for TCR signaling and regulation.
Ostman et al. Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density.
JP3991327B2 (ja) 甲状腺組織試料中の甲状腺癌細胞を検出する方法及び甲状腺癌の組織診断用組成物
Mizuno et al. MPTPδ, a putative murine homolog of HPTPδ, is expressed in specialized regions of the brain and in the B-cell lineage
CA2383244A1 (fr) Proteines kinases
US20070190581A1 (en) Density enhanced protein tyrosine phosphatases
JP2002142781A (ja) ヒト軟骨gp−39様遺伝子
JP2002515020A (ja) TNF−α転換酵素
Parries et al. The human urinary epidermal growth factor (EGF) precursor: isolation of a biologically active 160-kilodalton heparin-binding pro-EGF with a truncated carboxyl terminus
US5972674A (en) Stimulus-inducible protein kinase complex and methods of use therefor
CA2166479C (fr) Nouvelles tyrosine phosphatases a densite renforcee
AU3879700A (en) Hermansky pudlak syndrome protein-interacting proteins and methods of use thereof
KR100482249B1 (ko) 단백질 타이로신 포스파타아제의 세포내 도메인에 대한 항체
CA2537374A1 (fr) Nouvelles tyrosine phosphatases a densite renforcee
JP2003000249A (ja) クローディンによるMT−MMPsを介したproMMP−2活性化
US20020137170A1 (en) DSP-16 dual-specificity phosphatase
US20020127226A1 (en) Class of RPTPases: their structural domains and ligands
McCright The identification and characterization of B56, a new family of protein phosphatase 2A regulatory subunits
Giannelli et al. Metalloprotease–2 Cleavage of Laminin-5

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20150504