CA2165202A1 - Sous-unite de 170 kd de lectine d'entamoeba histolytica obtenue par recombinaison; methodes d'utilisation - Google Patents
Sous-unite de 170 kd de lectine d'entamoeba histolytica obtenue par recombinaison; methodes d'utilisationInfo
- Publication number
- CA2165202A1 CA2165202A1 CA002165202A CA2165202A CA2165202A1 CA 2165202 A1 CA2165202 A1 CA 2165202A1 CA 002165202 A CA002165202 A CA 002165202A CA 2165202 A CA2165202 A CA 2165202A CA 2165202 A1 CA2165202 A1 CA 2165202A1
- Authority
- CA
- Canada
- Prior art keywords
- epitope
- subunit
- bearing portion
- histolytica
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56905—Protozoa
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- General Physics & Mathematics (AREA)
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- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Une sous-unité lourde de 170 kDa produite par recombinaison de lectine d'adhésion Gal/GalNAc d'Entamoeba histolytica ou une partie porteuse d'épitopes de celle-ci peut être utilisée en tant qu'antigène dans l'analyse sérologique de l'infection par E.histolytica ou en tant que vaccin d'immunisation contre l'infection. La production par recombinaison s'effectue dans un système procaryote afin de produire des antigènes ou des immunogènes non glycosylés immunologiquement réactifs. Trois gènes codant les parties porteuses d'épitopes de la lectine sont également décrits.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7847693A | 1993-06-17 | 1993-06-17 | |
| US08/078,476 | 1993-06-17 | ||
| US13073593A | 1993-10-01 | 1993-10-01 | |
| US08/130,735 | 1993-10-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2165202A1 true CA2165202A1 (fr) | 1995-01-05 |
Family
ID=26760579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002165202A Abandoned CA2165202A1 (fr) | 1993-06-17 | 1994-06-17 | Sous-unite de 170 kd de lectine d'entamoeba histolytica obtenue par recombinaison; methodes d'utilisation |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0708923A4 (fr) |
| JP (1) | JPH09502165A (fr) |
| AU (1) | AU710439B2 (fr) |
| CA (1) | CA2165202A1 (fr) |
| WO (1) | WO1995000849A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6951917B1 (en) * | 1995-09-26 | 2005-10-04 | The United States Of America As Represented By The Department Of Health And Human Services | MHC-class II restricted melanoma antigens and their use in therapeutic methods |
| US7501501B2 (en) | 1995-09-26 | 2009-03-10 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | MHC-Class II restricted melanoma antigens and their use in therapeutic methods |
| AU2001295337A1 (en) * | 2000-10-20 | 2002-04-29 | Ian Crandall | E. histolytica-specific antibodies and clinical uses thereof |
| JP6799927B2 (ja) * | 2016-02-23 | 2020-12-16 | 古河電気工業株式会社 | 生体分子検出用試験キット、及びこれを用いた生体分子の検出方法、並びにこれらに用いられる生体分子検出用標識試薬 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5260429A (en) * | 1988-01-13 | 1993-11-09 | The University Of Virginia Alumni Patents Foundation | Purified DNA of the 170-kd surface Gal/GalNAc adherence lectin of pathogenic E. histolytica |
| US5004608A (en) * | 1988-01-13 | 1991-04-02 | The University Of Virginia Alumni Patents Foundation | Amebiasis vaccine |
-
1994
- 1994-06-17 CA CA002165202A patent/CA2165202A1/fr not_active Abandoned
- 1994-06-17 EP EP94920262A patent/EP0708923A4/fr not_active Withdrawn
- 1994-06-17 JP JP7502991A patent/JPH09502165A/ja active Pending
- 1994-06-17 WO PCT/US1994/006890 patent/WO1995000849A1/fr not_active Application Discontinuation
- 1994-06-17 AU AU71123/94A patent/AU710439B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPH09502165A (ja) | 1997-03-04 |
| WO1995000849A1 (fr) | 1995-01-05 |
| AU710439B2 (en) | 1999-09-23 |
| EP0708923A4 (fr) | 1998-07-08 |
| AU7112394A (en) | 1995-01-17 |
| EP0708923A1 (fr) | 1996-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |