CA2164895A1 - Flavored denture cleanser compositions - Google Patents

Abstract

The subject invention encompasses a flavored denture cleanser composition comprising from about 0.1% to about 50 % of a dry flavor powder system comprising, by weight of the system, from about 0.01% to about 60% of one or more flavors, and from about 40% to about 99.99% of one or more carriers; and from about 50% to about 99.9% of a denture cleanser; and wherein one or more flavors delivered by the dry flavor powder system are retained on a denture after cleaning with the flavored denture cleanser composition.

Description

Case 5518 FLAVORED DENTURE CLEANSER COMPOSITIONS

BACKGROUND OF THE INVENTION
sThe aim of a denture c1P~rl~Pr product is to clean the denture as fully and as quickly as possible and especially to remove the aCcl~mlll~tion of plaque, agino lS and bacterial deposits which collect while the denture is being worn.
To wear a denture which has not been cOlllpl Ply cleaned of plaque and bacterialdeposits is not only unh~g~laic but can also result in a detrimental effect on the 10mllcous ~ bl~ne within a short period of time. Moreover, deposits can lead to color change and malodor formation.
Self-cJe~ning denture 5Ie~ e~ ~ offer a convenient method for cleaning d-,.llul~s. Cleallse,~ in granule or tablet form are dissolved in water to form a denture clP~nser solution. The dentures are then soaked in this solution for a period 15of time and then rinsed before being reinse,led into the ~earel's mouth. It iscommon, however, that the user of this method will subsequently rinse the dentures in moulhw~sl, or brush them with or without toothpaste before leinse, lion to impart a pleasing flavor to the user's mouth. Thelerore a need exists for a flavored denture cle~n~r which can provide the denture wearer with noticeable flavor benefit after 20their dentures have been cleaned by a solution cle~n~er regimen and avoid the need for s Ibseq~lPnt short term product use.
It has been discovered that a dry flavor powder system comprising certain flavors can be h~co",o,aled in a self-cle~ni~ denture cle~n~er composition. It has also been discovered that this flavored denture cle?n~er composition can deliver2snotic~ble flavor to the denture wearer even after the dentures are cleaned in the ~I~P11~er solution.
It is therefore an object of the invention to provide a flavored denture c1e~n~r which effectively cleans dentures through so~ing in a cle~n~Pr solution. It is also an object of the invention to provide a flavored denture cle~n~er composition 30where the flavor survives the rigorous cle~nin~ conditions in the cle~n~çr solution and delivers noticeable flavor to the denture wearer a~er the cle~nin~ regi,llell.
These and other objects of the present invention will become readily app&,elll from the det~iled description which follows.

3s SUMMARY OF THE rNVENTION

2~ 4893 The present invention relates to a flavored denture t~ ncer composition con.~..ising from about 0.1% to about 50% of a dry flavor powder system compl;s;llg, by weight of the system, from about 0.01% to about 60% of one or more 40 flavors, and from about 40/O to about 99.99% of one or more carriers; and from about 50% to about 99.9/O of a denture c~ , and wL~eil1 one or more flavors delivered by the dry flavor powder system are retained on a denture after cle.~ g with the flavored denture c~e~nu,- composition. The dry flavor powder system is incol~oraled in the denture ~I~An~er to provide a denture cle~ncer composition which 4s delivers noticeable flavor to the denture wearer after the dentures are cleaned by present r1e~nc~r compositions.
DETAII,ED DESCRIPTION OF THE INVENTION
The present invention comprises a dry flavor powder system which is incorporated in a denture cle~cf~r The invention compositions provide denture so c~e~ni~ in the form of powders, granules or tablets. The tablets can be in the form of monolayer tablets or can comprise two or more discrete layers. The invention compos lions can be dissolved in water to form a denture cleanser solution or form~ ted as liquids or pastes.
The term "denture" as used herein means all those removable orthodontic ss appl;s~ees such as partial and full sets of false teeth, dental plates, orthodontic ;~in~.~, andbridges.
The term "ml" as used herein means milliliter.
The term "g" as used herein means gram.
Dry Flavor Powder System The dry flavor powder system comprises one or more flavor oils or flavor .-.h.omic~lc incorporated into a dry powder through the use of one or more carriers.
The term carriers, as used herein, means any material suitable for incorporating an oil or other substance to a dry form. The one or more flavors delivered by the dry flavor powder system are l~lained on a denture after r1e~ning with the flavored denture6s r1eP-~ r composition. The dry flavor powder system delivers noticeable flavorbenefit to the denture wearer after their dentures have been cleaned by the present flavored denture c1e~nc~r compositions.
The dry flavor powder system may be formed by any technique applopliate for incorporating an oil or other subsl~nce in dry powder form. Plerel-ed teçhniques 70 are air-s~lspen~ion cooling, spray-drying, and microen~rsl~tiQn. Such techniques are generally desclil,ed in Kirk-Othmer~ Encyclopedia of Chemical Technolo~y, Third Edition, vol. 13 pp. 470-484.

- 21C~895 The dry flavor powder system also comprises various carriers which are used to il~cG.~Grale one or more flavors to powder conci~tency. Illustrative, but non-7s limiting materials useful in the present invention as carriers include maltodeYtrin;starch based matrices such as co.,.~larch, cyclodextrin in~ ling aromatics, alcohols, non-ionic species and aliphatic materials; sugar solids such as mono-, di- and polysaccharides; and various gums such as gum arabic, gum acacia and guar gum.
Mq1tod~Ytrin is prerelled for use in the present invention. Carriers are used at levels 80 of from about 40% to about 99.99%, pl~;r~lably from about 50% to about 80%, and most prer~,~bly from about 75% to about 95% by weight of the dry flavor powder system.
Various flavors can be used in the dry flavor powder system of the present invention. Illustrative but non limiting examples of such flavors include peppermint 8s such as Mentha piperita; spe&ll"inl such as Mentha cardiaca and Mentha spicata;
other Mentha varieties ~Y~ di~ Mentha arvensis: hydrocarbons such as limonene, cd yopl.~llene, --y-cene, and h--rmllçne; alcohols such as menthol, linalool, 3-decanol, and pinocarveol; esters such as nlt;lllllyl acetate, benzyl isobutyrate, and 3-octyl acetate; ketones such as peperitone, menthone, spicatone, and l-carvone; aldehydes so such as acetq~ hyde, 3-h~Yqnql or n-octanal; oxides such as menthofuran or pepertione oxide; acids such as acetic and ocenoic; phenols such as thymol; sulphides such as dimethyl sulphide; oxides such as carvyl acetate-7,7 oxide; coolants such as pa ~---c~ Al-e carboxyamide agents, N-ethyl-p-mçnthq-ne-3-carboyqm:1e~ and 3-l-menth4~y~opalle-1,2-diol; wintergreen; anise; citrus; fruit flavors; rinnq-m~ n;ss e~genQ!; ionone; ~qnetholc; eucalyptol; vanillin; and mixtures thereof.
Pl~;r~lled are ~,-linl, alcohols such as menthol, linalool, 3-decanol, and pinocarveol; ketones such as peperitone, menthone, spicatone, and l-carvone;
aldehydes such as 3-h.oYvn<q,l; oxides such as menthofuran; phenols such as thymol;
slllrh:1es such as ~l;...e~.ll.y-l sulphide; coolants such as param~nthqne carboxyamide oo agents, N-ethyl-p-...e..ll.Ane-3-carboxq-mi1e, and 3-l-menthox~.,opane-1,2-diol;
anise; citrus; fruit flavors; ~irmqmon; eugenol; ionone; anethole; eucalyptol; and mixture thereof. Most plerel,ed are anise, m~nthol, menthone, thymol, ionone, n~"oll~ and mixtures thereo Pep,oe"""ll such as Mentha piperita, and/or ~ea,ll--lll such as Mentha spicata are most pr~;re"~d when combined with one or 05 more of anise, menthol, menthone, thymol, ionone, çinnqmon, and mixtures thereof.
Flavors are used at levels of from about 0.01% to about 60%, preferably from about 20% to about 50% and most plerelably from about 5% to about 25%, by weight of the dry flavor powder system.

21C48gS

` -The dry flavor powder system is used in the present invention at levels of o from about 0.1% to about 50%, prere.~bly from about 2% to about 40%, and most preferably from about 5% to about 25%, by weight of the flavored denture cle9n~r o~ n.
Denture Cleanser The denture cle~n~r component of the invention compositions conll,-ises a 5 b'e~-hin~ agent, a peroxyacid bleach precursor and a solid base material. Each of these will be ~ c..ssed further below. The denture rleqn~r is used in the present invention at levels of from about 50% to about 99.9%, preferably from about 60% to about 98%, and most plefelably from about 75% to about 95%, by weight of the ~oled denture cle?n~,r composition.
120 The bl~aching agent takes the form of the inorganic persalt and can be s~lected from any of the well-known bleachi~ agents known for use in denture cle~ such as the alkali metal and an-ll.ol~ium perslllf~tçs~ perborates, pe.c~l,onates and perphosphqtes and the alkali metal and alkaline earth metal peroxides. Illustrative, non-limiting examples of such ble~chin~ agents include pot~ m ammonium, sodium and lithium persulfates and perborate mono- and tetrahydrates, sodium pyrophosphate peroxyhydrate and m~l~s~ C~lci~
strontium, and zinc peroxides. Plefelled are alkali metal pers~lf~tçs~ pe-l,olates and ~lules thereo The amount of bleA~hin~ agent in the denture rle~n~er composition is generally from about S% to about 70%, and preferably from about 10% to about 50/0. In compositions comprising a mixture of alkali metal persulfates and perborates, the overall persulfate:perborate ratio is suitably from about 5:1 to about 1:5, and preferably from about 2:1 to about 1:2.
The organic peroxyacid precursor can be generally defined as a compound 135 having a titre of at least 1.5ml of 0. lN sodium thios~lf~te in the following peracid formulation test.
A test so! ltion is pl~parèd by dissolving the following materials in 1000 mls di~tilled water:
Sodium pyrophosphate 2.5g Sodium perborate 0.615g (having 10.4% available oxygen) Sodium dodecylh~n7~one sulphonate 0.5g To this solution at 60C an amount of activator is added such that for each atom of available oxygen present one molecular equivalent of activator is introduced.

216~895 The mixture obtained by addition of the activator is vigorously stirred and ~ ed at 60C. Mer S m~ ltes from addition, a lOOml portion of the solution is withdrawn and imme-liqtely pipcUed onto a mixture of 250g cracked ice and 15ml glacial acetic acid. Pot~c~;~lm iodide (0.4g) is then added and the liberated iodine is ;--...-~Ai~lPIy titrated with O.lN sodium th:cls~lrh~te with starch as indi~tor until first 50 d;sappf~ance ofthe blue color. The amount of sodium thiosulphate solution used in ml is the titre of the bleach activator.
The organic peracid precursors are typically compounds Co~ p. one or more acyl groups, which are ~sceplible to pelhydrolysis. The prcre"cd activatorsare those of the N-acyl or O-acyl compound type cQ~IA~ np an acyl radical R-CO
55 wllclcill R is a hydrocarbon or sub~tituted hydrocarbon group having prerer~bly from about 1 to about 20 carbon atoms. Examples of suitable peracid precursors include:
1) Acyl or~noAm;des of the formula RCONR1R2, where RCO is a carboxylic acyl radical, Rl is an acyl radical and R2 is an organic radical, as disclosed in U.S. 3,117,148. FYAmples of compounds falling under this group include: N,N-60 diacetylaniline and N-acetylphthqlim:1ç; N-acylhydantoins such as N,N'-diacetyl-5,5-d",.~,ll,ylhy l~ntoin; polyacylated alkylene ~iz~;nf s such as N,N,N'N'-tel~&cctylethylene~ mine (NTAED") and the corresponding methylenf,~i~mine (nTAMD") and kf.. rthylçne~iqmi-le ("TAHD") derivatives; acylated glycolurils such as tcl, ~cetylglycoluril.
16s 2) Acylated s~lphon~mi~les such as N-methyl-N-ben_oyl-mf nthqne sulphonal~"de and N-phenyl-N-acetyl ..,~ e sulphonamide.

3) Carboxylic esters such as phenyl acetate, sodium acetoxy benzene s~lrh~natç, tricloroctl,~ et~tç, sorbitol hf~Y~Get~te, fructose pçnt~^cet~te, p-nitrobfn7~ldçhyde ~iacetqte, isopropencyl acetate, acetyl aceto hydlo~ullic acid and 70 acetyl salicylic acid and esters of a phenol or s~lbstituted phenol with an alpha-chlorinated lower aliphatic carboxylic acid such as chloroacetylphenol and chloroacetylsalicylic acid.

4) Calllo~ylic esters having the general formula AcL wherein Ac is the acyl moiety of an organic carboxylic acid comprising an optionally substit~lte~ linear or 75 I~ ched C6-C20 alkyl or alkenyl moiety or a C6-C20 alkyl-substituted aryl moiety and L is a leaving group, the co~ug~te acid of which has a pKa in the range from 4 to 13, for e ~le oxyl,e~-7f e,.llfonate or oxyb~ ~.o~le. ~Icr~cd compounds of this type are those wherein:
a) Ac is R3-CO and R3 is a linear or branched alkyl group 180 co.. l~ g from 6 to 20, preferably 6 to 12, more prcfc,ably 7 to 9 carbon atoms and wherein the longest linear alkyl chain çYtçn~ing from and inc~

216489~

the carbonyl carbon co~ c from 5 to 18,p,ere~bly from 5 to 10 carbon atoms, R3 optionally being slbstitl~ted (preferably alpha to the ca-l,onyl moiety) by Cl, Br, OCH3 or OC2Hs. Examples of this class of material include sodium 3,5,5-lli-"e~ rlhexanoylu~benzene sulfonate, sodium 3,5,5-l~il".,~ lhexanoyloxyben-zoate, sodium 2-ethylhexanoyl ox~il,el~ene-sulfonate, sodium nonanoyl oxy-benzene sulfonate and sodium octanoyl o"yb~n,e~-es~lffinate, the acyloxy group in each in.ct~nce preferably being p-substitute~1;
b) Ac has the formula R3(AO)mXA wherein R3is a linear or b,~ched alkyl or alkylaryl group conl~ ing from 6 to 20, preferably from 6 to 15 carbon atoms in the alkyl moiety, R5 being optionally substituted by Cl, Br, OCH3 or OC2Hs, AO is o~y~;~l-ylene or o~yl lO~ ylene, m is from 0 to 100, X is O, NR4 or CO-NR4, and A is CO, CO-CO, R6-CO, CO-R6-CO or CO-NR4-R6-CO ~hereil~R4is C1-C4 alkyl and R6 is alkylene, alkenylene, arylene or alkarylene co~ il-g from 1 to 8 carbon atoms in the alkylene or alkenylene moiety. Bleach activator compounds of this type include carbonic acid derivatives of the formula R3(AO)mOCOL, succinic acid derivatives of the formula R3OCO(CH2)2COL, glycollic acid derivatives of the formula 200 R30CH2COL, h~droAy~,.opionic acid derivatives of the formula R3OCH2CH2COL, oxalic acid derivatives of the formula R30COCOL, maleic and fumaric acid derivatives of the formula R30COCH=CHCOL, acyl aminocaproic acid derivatives of the formula R3CONRl(CH2)6COL, acyl glycine derivatives of the formula R3CONRlCH2COL, and amino-6-20s o~Yos~rroic acid derivatiws of the formula R3N~Rl)CO(CH2)4COL. In the above, m is preferably from 0 to 10, and R3is preferably C6-C12, more prefe~;~ly C6-Clo alkyl when m is zero and Cg-Cls when m is non-zero.
The leaving group Lis as defined above.

5) Acyl-cyanurates, such as triacetyl- or tribenzoylcyanurates, as disclosed 210 in US Patent No. 3,332,882.

6) Optionally substituted anhydrides of benzoic or phthalic acid, for ~mp1e benzoic anhydride, m-chlorobenzoic anydride and phthalic anhydride.
Of all the above, pfere.-ed are organic peracid precursors of types l(c) and 4(a).
215 The level of peroA~ cid bleach precursor by weight of the denture cle~n.~or c~mrosition is prere.ably from about 0.1% to about 10%, more preferably from about 0.5% to about 5%.

-- 21C189~

_ The solid base material and, in plt:rt:"ed embotiim~ntc~ the bleach precursor ag~ e.ales also incol~o~ale an effervescence generator. The effervesc~-nce 220 generator utilized in the compositions herein can be s~lected from generators which are effective under acid, neutral or allcaline pH conditions, but p-ert,ably it consists of a combil alion of a g,el e.~tor which is effective or most effective under acid or neutral pH conditions and a generator which is effective or most effective underalkaline pH conditions. Effervescence gene,~lo-s which are effective under acid or 225 neutral pH conditions include a col"binalion of at least one alkali metal carbonate or bic&ll,onale, such as sodium bicarbonate, sodium carbonate, sodium sesquicarbonate, potassium ca,l~onate, potassium bicarbonate, or mixtures thereof, in a~lmixh1re with at least one non-toxic, physiologically-accepta~le organic acid, such as tartaric, fumaric, citric, malic, maleic, gluconic, succinic, salicylic, adipic or sulphamic acid, 230 sodium fumarate, sodium or poPcsillm acid phosphates, betaine hydrochloride or ixlures thereof. Malic acid is p.er~" ed.
Effervescence generators which are effective under alkaline pH conditions include persalts such as alkali and alkaline earth metal peroxoborates as well as pelbolales~ persulphates, perca,l.onàles, perphosphates and mixtures thereo An 235 ~A~UIIple of such effer~escence generators in~ des a mixture of an alkali metal perborate (anl,~d,ous, mono- or tetrahydrate) with a monopersulphate such as Caroat~ marketed by E I DuPont de Nemours Co. and which is a 2:1:1 mixture of ,..ollope~ lphate, potassium sulphate and potassium bisulphate and which has an active oxygen content of about 4.5%.
240 In highly prefe"ed compositions, the solid base material incorporates both a (bi)cd~lJol1d~e/acid effervescent couple and a perborate/persulphate oxygen effervescçn~e generator while the bleach precursor agglomerates incorporate a (bi)~a l,onale/acid and optionally a peroxoborate oxygen effervescence generator.
The coml)inâlion of generators is important for achieving optimum ~iicsol~ltion 245 characteristics and pH conditions for gene,~tion of the peroxyacid bleach and for achieving optimum ele~ ng and a,lti",icrobial activity. The (bi)carbonate co",pol1e,lls generally comprise from about 5% to about 65%, plt;r~l~bly &om about 25% to 55% of the denture r1eAn~r composition; the acid components generally co",p,ise from about 5% to about 50%, preferably from about 10% to about 30% of 250 the denture cleAllcer composition.
In pre~"~;d embo~iments herein, the inorganic ble?clling agent comprises an alkali metal pe,l,orate and the solid base material comprises at least one co",ponent phase having an acid or neutral pH in aqueous merii~-m; said at least one phase having incollJota~e therein at least a portion ofthe alkali metal perborate.

-' 21648g5 ~_ 8 2ss For optil.lunl ~ntip~^q~le and Antihacterial pt;.ro"llal~ce, the cle~nQi~
co",pos;lion is preferably dç.signed in such a way that the bleach precursor agglo---e.ates dissolve or dispelse in water more slowly or later than the acid or neutral phase in order to provide, on placing the cleAnin~ composition in water, an initial pH in the acid or neutral range, p~ererably from about 2 to about 7.5 and 260 preferably from about 5 to about 7. Moreover, it is prerelled that the bleach precursor agglomerates have an alkaline pH in aqueous medi~m and be present in ~fficient amount in order to shift, upon CG .~letion of effervescence, the pH of the nqueous ...e~ .. into the alkaline range, preferably to a pH of from about 8 to about 10, this pH being prerellt;d for reasons of cleAnin~ pelro~-lallce and solution clarity.
26s The initial acid or neutral pH should be ~ A;I-çd for a time from about 30 second to about 5 minlltes~ preferably from about 1 minute to about 3 minlltes Efferve3ce~ce is preferably co pleted in from about 30 seconds to about 4 minl~tes preferably from about 1 to about 3 minlltes of the pH being shifted into the alkaline range.
270 The slower r~i~colutiQn rate of the bleach precursor agglomerates conlpaled with the tablet matrix base material can be achieved in various ways, for example, by the use of alkaline salts or compounds which are inherently sparingly or slowly soluble such as al~,~dr~lls sodium c~l,onale, calcium carbonate, calcium hydroxide, n~a~.es: .... oxide, or mqgnçQ;~Im hydroxide carbonate or by mixing or comp-es~il-g 27s the bleach pre;u,~r Aeglomerate co"lpollellls with a filler which has a slow.liQ-Q~lution rate such as anhydrous sodium sulfate and slowly water-soluble polymers, for example, proteins, ce~ lose ethers, cellulose esters, polyvinyl alcohol, alginic acid esters, vegetable fatty pselldocolloidal character. Moreover, the relative rate of dissolution ofthe bleach precursor agglomerates and tablet matrix can be additionally 280 controlled by applupl;ale formulation and distribution of the binding/agglol,lt;l~lil~
and effervescent components of the solid base material and bleach precursor agglomerate.
In another embodiment of the invention which is plerelled from the view point of providing more rapid tablet dissolution, the inorgal~ic bl~ac1ling agent 28s comprises an alkali metal perborate and the solid base material comprising at least one component phase having an alkaline pH in aqueous me~ m with at least one phase having incoll,o,aled therein at least a portion of the alkali metal perborate.
For optimum CleAn;~P. pelro""al-ce, the bleach precursor agglomerates in this emho~limçnt plertlably have an acidic or neutral pH in aqueous ~.,e~ " and 290 ~ itionqlly incorporate an agglo~.~e.aling agent and an effervescçnce generator.
Overall, for optimum di~.solllti~n, stability, and pe,ro",.ance, the bleach ple~u-~or 216~8g5 -a~glQInerates and the solid base material preferably have a pH dirrerence in aqueous ".P1;...~ of from about 0.5 to about 2 pH units. The level of bleach precursor ag~lo...e.~es is plere.~bly from about 1% to about 20%, and more preferably from29sabout 5% to about 15%, by weight ofthe C1~An~ g tablet.
The bleach pr~;ut~or a~lomerates prt;r~lled for use herein generally comprise a binder or agglol"t;,aling agent in a level of from about 1% to about 40%, more especially from about 10% to about 30% by weight of the denture c1eA-l.cer.Sl-it-b'e A~lomerating agents include polyvinylpyrrolidone, poly(oxyethelen) of 300moleclllAr weight 20,000 to 500,000, polyethyleneglycols of molecular weight of from about 1000 to about 50,000, Carbowax having a molecular weight of from 4000 to 20,000, nonionic surfActAntc fatty acids, sodium carboxymethyl cellulose, gelatin, fatty alcohols, phosphAtes and polyphosphates, clays, Al~minosilicates and polymeric polycarboxylates. Of the above, polyethyleneglycols are highly prere"ed, 30sçspeçiAlly those having a molecular weight of from about 1,000 to about 20,000.
~lere"ed from the viewpont of optimum dissolution and pH characteristics are bleach precursor agglomerates which comprise from about 10% to about 75%, pler~lably from about 20% to about 60% by weight thereof of peroxyacid bleach precursor; from about 5% to about 60%, preferably from about 5% to about 50%, 310more preferably from about 10% to about 40% of a (bi)carbonate/acid effervescent couple; from about 0% to about 20% of a peroxoborate; and from about 5% to about 40%, preferably from about 10% to about 30% of an agglo"lt;. dLi~lg agent.The final bleach precursor granules desirably have a particle density (individual particle basis) of at least 1.05 g/cc and an average particle size of from 315about 500 to about 1500, preferably from about 800 to about 1200 um, this being valuable from the viewpont of optimum dissolution pe~ro"..ance and aesthetics.
The compositions of the invention can be supplcm~nted by other usual components of ç1~An~ e table formulations, especially surfActA-ntc ch~l~tin~ agents, e~ es, ~ tu~, sweeteners, tablet binders such as the above specified bleach 320 precursor agglo...e.aling agents, especiAlly polyethyleneglycols having a molecular weight of from about 12,000 to about 30,000, foam deplessa--ls such as dill..,ll.ylpolysiloxanes, foam stabilizers such as the fatty acid sugar esters,p,~,se-~ali~es, lubricants such as talc, m~n~sillm stearate, finely divided amorphous pyrogenic silicas, etc. The free moisture content of the denture cle~n.cer composition 32s is desirably less than about 1% and especially less than about 0.5%.
The surface active agent used in the compositions of the invention can be s~ ed from the many available that are co-,-palible with the other ingredients of the denture ~le~nce ~ both in the dry state and in solution. Such materials are believed to improve the effectiveness of the other ingredients of the cGn-pGsit;on by aiding their 330 pe~ .alion into the interdental surfaces. Also, these materials aid in the removal of food debris ~ttnched to the teeth. Between 0.1 and 5 percent by weight of the dry c~lll~s.lion of a dry powder or grandular anionic surface active agent, such as sodium lauryl sulfate, sodium N-lauroylsarcos;rl-s~te, sodium lauryl sulfonretste or dioctyl sodium sulfosucçinste or ricinoleyl sodium sulfos~lGçinsite, may, for example, 33s be inrl~lded in the colllpo3;tion and preferably the surface active agent col"p,;ses b~ n 2 and 4 percent ofthe composition.
Suitable cationic, non-ionic and ampholytic surface active agents incl~lde, for ~A~I_rl~, quaternary a~.. on: lm compounds such as cetyltrimethyla"l"lonium bromide, conden~stio~ products or alkylene oxides such as ethylene or propylene 340 oxide with fatty alcohols, phçnQle fatty amines or fatty acid alkanol~m;dçs, the fatty acid alkanol amides themselves, esters of long-chained (Cg-C22) fatty acids withpolyalcohols or sugars, for eA~Il~;lc, glycerylmonostearate or saccharosemonolaurate or sorbitolpolyoAy~lllylen~monQ- or di-stearate, be~ e sulphobelailles or long-chain alkyla,l,h~ocall,uAyl;c acids.
34s Ch~l~ting agents bçnefiri~lly aid rleqnin~ and bleach stability by keeping metal ions, such as c~lcil-m, mqgn~ei~lm and heavy metal cations in solution.
F.Y~mr~s of suitnl?le çhel~ting agents include sodium tripolyphosphate, sodium acid pyrophosph~te, tetr~eo~illm pyrophosphate, an~nopolycarboxylates, such as nitrilotriacetic acid and ethylçne~ mine tetracetic acid and salts thereof, and 3so polyphosphonates and ~I~.nopolyphosphon~tes such as hyd~oAyelhql-edirhosphonic acid, ethylen~~ e t~ ~lL~lenephosphc - ~ acid, diethylenet,;~ epçnt~-methylenephosphQnic acid and salts thereof. The chel~ting agent selected is not critical except that it must be co,l"~alil,le with the other ingredients of the denture when in the dry state and in aqueous solution. Advantageously, the 355 c~ -p. agent col"p,ises between 0.1% and 60% by weight of the denture Cle~ne~r and pr~r~,~bly betv~een 0.5% and 30%. Phosphonic acid chPl~tinp. agents, however, preferably comprise from about 0.1% to about 5%, prere,ably from about 0.1% to about 0.5% by weight ofthe denture cle~n~r.
Enzymes suitable for use herein are exemplified by proteases, ~ ee 360 a"yld~s, lipases, dcAlland5e5, mn~ ceQ ~I--c~n~eee, etc.
A prerel-ed embodiment of the denture rle~ncer encompqeses a cle~n tablet coll")-ising visually discrete agglomerated particles of an organic peroxyacid bleach precursor dispersed in a water-soluble or water-dispersible matrix comprising an inOI~alliC persalt bl~achin~ agent and a solid base material which in the presel~ce 365 of water releases carbon dioxide or oxygen with effervescçnce. Other embodirn~nts 216l895 include the cle~n~er compositions described in U.S. Patent 5,055,305, to Young, issued 10/8/91, which is incorporated herein by ~e~lence.
The following ey~rnr~es further describes an embodiment within the scope of the present invention. These examples are given solely for the purpose of illustration 370 and are not to be construed as a limit~tion of the present invention as many variations thereof are possible without departing from the spirit and scope of the present invention. Pel~ ~t~ges are by weight unless otherwise stated.
EXAMPLE I
Denture Cleanser Mixture Weight %
37s Malic acid 13.97 Sodium bicarbonate 24.69 Sodium carbonate 6.45 Pot~ m l-,ollopel~.llphate 12.90 Sodium perborate 16.45 380 EDTA(a) 1.55 Polyethylene glycol 20000 6.66 Polyethyleneglycol 10000 1.55 SDBS(b) 0.55 DRMS(C) 0.27 38s Wasag 7(d) 0.09 Wasag 15(e) o 09 Silica 1.39 Syloid 0 35 Sodium carbonate 3.71 390 Sulphamic acid 1.89 TAED(f) 3.87 Color mix 1.45 Dry Powder Flavor System(g) 2.12 Flavors Dry Weight %
3ss Menthol 62.5 Anise 31.25 Ionone 6.25 (a) Ethylenedi~ netetraacetic acid 400 (b) Sodium dodecyl ben7Pnesulfonate (c) Diasodium riçino'~midQ monoeth~nolamine sulfosuc~in~te (d) 70% Sucrose P~lmit~te/30% Sucrose Stearate 216~895 -(e) 70% Sucrose Stearate/30% Sucrose P~lrnit~te (f) Tetraacetylethylene ~i~n ine 405 (g) Spray dried flavors (20% flavor loaded, 80% m~ltodeYtrin) EX~MPLE II
Denture Cleanser Mixture Weight %
Malic acid 13.97 410 Sodium bic~ e 24.69 Sodium cd,bona1e 6.45 Potassium monopc,~ulphate 12.90 Sodium pe~bo,~te 16.45 EDTA(a) 415 Polyethylene glycol 20000 6.66 Polyethylene glycol 10000 1.55 SDE~S(b) 0.55 DRMS(C) 0.27 Wasag 7(d) o 09 420 Wasag 15(e) 0.09 Silica 1.39 Syloid 0.35 Sodium carbonate 3.71 Slllrh~mic acid 1.89 425 TAED(f) 3.87 Color mix 1.45 Dry Powder Flavor System(g) 2.12 Flavors Dry Weight %
Menthol 40.0 430 Peppe~"linl 20.0 Cinnamon 20.0 Anise 40.0 (a) Ethylene~;h...;.-eletraaceticacid 435 (b) Sodium dodecyl ~e ~ne~lJlfonate (c) Diasodium ricinoleamido monoetll~nolamine sulfosucçin~te (d) 70% Sucrose p~lnnit~te~30% Sucrose Stearate (e) 700/o Sucrose Stearate/30% Sucrose P~lmit~te (f) Tetraacetylethylene rli~1nin~

~lC48gS

440 (g) Spray dried flavors (20% flavor loaded, 80% maltodextrin) F-Y~n1P'eS I and II may be made as follows: Mix toge~hPr applo,.;~lely 3.04 ~ams of denture cle~n~r mixture and 0.32 grams dry flavor powder system. In a clean receptacle, place appro~;...~ttoly lSOml water and the flavored denture cle~n~.r ..u~lure. Stir or shake and place denture in solution for at least 20 mimltes. Rinse 44s with tap water and insert in mouth.

Claims (9)

1. A flavored denture cleanser composition comprising (a) from 0.1% to 50% of a dry flavor powder system comprising, by weight of the system, from 0.01% to 60% of one or more flavors, and from 40% to 99.99% of one or more carriers; and (b) from 50% to 99.9% of a denture cleanser;
and wherein one or more flavors delivered by the dry flavor powder system are retained on a denture after cleaning with the flavored denture cleanser composition.

2. The composition accolding to Claim 1 wherein the flavor is selected from the group consisting of spearment, alcohols such as menthol, linalool, 3-decanol, and pinocarveol; ketones such as peperitone, menthone, spicatone, and 1-carvone; aldehydes such as 3-hexanal; oxides such as menthofuran; phenols such as thymol; sulphides such as dimenthyl sulphide; coolants such as paramenthane carboxyamide agents, N-ethyl-p-menthane-3-carboxamide, and

3-1-menthoxypropane-1,2-diol; anise; citrus; fruit flavors; cinnamon; eugenol;
ionone; anethole; eucalyptol; and mixture thereof.

3. The composition according to Claims 1 or 2 wherein the composition is in the form of a tablet.

4. The compositions according to Claims 1-3 comprising from 2% to 40% of a dry flavor powder system comprising, by weight of the system, from 20% to 50% of one or more flavors, and from 50% to 80% of one or more carriers;
and from 60% to 98% of a denture cleanser; and wherein one or more flavors delivered by the dry flavor powder system are retained on a denture after cleaning with the flavored denture cleanser composition.

5. The composition according to Claims 1-4 wherein the flavor is selected from the group consisting of anise, menthol, menthone, thymol, ionone, cinnamon, and mixtures thereof.

6. The composition according to Claims 1-5 wherein the dry flavor powder system is produced by spray drying.

7. The composition according to Claims 1-6 where the carrier is selected from the group consisting of maltodextrin, cornstarch, cyclodextrin, gum arabic, gum acacia and guar gum.

8. The composition according to Claims 1-7 wherein the denture cleanser comprises a bleaching agent, a peroxyacid bleach precursor, and a solid base material.

9. The composition according to Claims 1-8 wherein the composition is in the form of a monolayer tablet.