CA2162149C - Antibodies to p-selectin and their uses - Google Patents

Antibodies to p-selectin and their uses Download PDF

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Publication number
CA2162149C
CA2162149C CA002162149A CA2162149A CA2162149C CA 2162149 C CA2162149 C CA 2162149C CA 002162149 A CA002162149 A CA 002162149A CA 2162149 A CA2162149 A CA 2162149A CA 2162149 C CA2162149 C CA 2162149C
Authority
CA
Canada
Prior art keywords
humanized
selectin
variable region
light chain
immunoglobulin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002162149A
Other languages
English (en)
French (fr)
Other versions
CA2162149A1 (en
Inventor
Robert W. Chesnut
Margaret J. Polley
James C. Paulson
S. Tarran Jones
Jose W. Saldanha
Mary M. Bendig
Michael Kriegler
Carl Perez
Robert Bayer
Michael Nunn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aeres Biomedical Ltd
Original Assignee
Aeres Biomedical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/004274 external-priority patent/WO1993021956A1/en
Priority claimed from US08/202,047 external-priority patent/US5800815A/en
Application filed by Aeres Biomedical Ltd filed Critical Aeres Biomedical Ltd
Priority claimed from PCT/US1994/004935 external-priority patent/WO1994025067A1/en
Publication of CA2162149A1 publication Critical patent/CA2162149A1/en
Application granted granted Critical
Publication of CA2162149C publication Critical patent/CA2162149C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564—Selectins, e.g. CD62
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA002162149A 1993-05-04 1994-05-04 Antibodies to p-selectin and their uses Expired - Fee Related CA2162149C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
PCT/US1993/004274 WO1993021956A1 (en) 1992-05-05 1993-05-04 Antibodies to p-selectin and their uses
WOPCT/US93/04274 1993-05-04
US5729293A 1993-05-05 1993-05-05
US08/057,292 1993-05-05
US08/202,047 US5800815A (en) 1903-05-05 1994-02-25 Antibodies to P-selectin and their uses
US08/202,047 1994-02-25
PCT/US1994/004935 WO1994025067A1 (en) 1993-05-04 1994-05-04 Antibodies to p-selectin and their uses

Publications (2)

Publication Number Publication Date
CA2162149A1 CA2162149A1 (en) 1994-11-10
CA2162149C true CA2162149C (en) 2007-07-10

Family

ID=26736298

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002162149A Expired - Fee Related CA2162149C (en) 1993-05-04 1994-05-04 Antibodies to p-selectin and their uses

Country Status (8)

Country Link
CN (1) CN1124928A (cs)
CA (1) CA2162149C (cs)
CZ (1) CZ287295A3 (cs)
HU (1) HUT75894A (cs)
NO (1) NO954403L (cs)
NZ (1) NZ266934A (cs)
PL (1) PL311666A1 (cs)
SK (1) SK137795A3 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY28886A1 (es) * 2004-05-10 2005-12-30 Boehringer Ingelheim Int Anticuerpos que consisten en polipéptidos y derivados conprendiendo tres secuencias conteniendo respectivamente los siguientes números de seq. id: 1-3 y 4-6; 7-9 y 10-12 y 13-15 ó 16-18
EP2654781B1 (en) * 2010-12-21 2018-01-24 Selexys Pharmaceuticals Corporation Anti-p-selectin antibodies and methods of their use and identification
CN113952468B (zh) * 2021-09-26 2023-07-07 中国人民解放军空军军医大学 一种治疗心肌缺血再灌注损伤的环孢菌素a纳米药物

Also Published As

Publication number Publication date
CN1124928A (zh) 1996-06-19
NO954403L (no) 1996-01-03
HUT75894A (en) 1997-05-28
PL311666A1 (en) 1996-03-04
CA2162149A1 (en) 1994-11-10
HU9503156D0 (en) 1996-01-29
CZ287295A3 (en) 1996-05-15
NZ266934A (en) 1997-07-27
NO954403D0 (no) 1995-11-03
SK137795A3 (en) 1996-11-06

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Legal Events

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EEER Examination request
MKLA Lapsed