CA2160704A1 - Administration d'acide nucleique au niveau du systeme oculaire - Google Patents

Administration d'acide nucleique au niveau du systeme oculaire

Info

Publication number
CA2160704A1
CA2160704A1 CA002160704A CA2160704A CA2160704A1 CA 2160704 A1 CA2160704 A1 CA 2160704A1 CA 002160704 A CA002160704 A CA 002160704A CA 2160704 A CA2160704 A CA 2160704A CA 2160704 A1 CA2160704 A1 CA 2160704A1
Authority
CA
Canada
Prior art keywords
ribozyme
rna
nucleic acid
carbopol
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002160704A
Other languages
English (en)
Inventor
Sean M. Sullivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sirna Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2160704A1 publication Critical patent/CA2160704A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CA002160704A 1993-04-28 1994-04-27 Administration d'acide nucleique au niveau du systeme oculaire Abandoned CA2160704A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5472293A 1993-04-28 1993-04-28
US08/054,722 1993-04-28
PCT/US1994/004609 WO1994024983A2 (fr) 1993-04-28 1994-04-27 Apport d'acide nucleique aux tissus oculaires

Publications (1)

Publication Number Publication Date
CA2160704A1 true CA2160704A1 (fr) 1994-11-10

Family

ID=21993084

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002160704A Abandoned CA2160704A1 (fr) 1993-04-28 1994-04-27 Administration d'acide nucleique au niveau du systeme oculaire

Country Status (4)

Country Link
EP (1) EP0695186A1 (fr)
AU (1) AU6714094A (fr)
CA (1) CA2160704A1 (fr)
WO (1) WO1994024983A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6146886A (en) 1994-08-19 2000-11-14 Ribozyme Pharmaceuticals, Inc. RNA polymerase III-based expression of therapeutic RNAs
US6040295A (en) * 1995-01-13 2000-03-21 Genemedicine, Inc. Formulated nucleic acid compositions and methods of administering the same for gene therapy
JP2003528024A (ja) * 1997-12-16 2003-09-24 バレンティス・インコーポレーテッド 製剤化された核酸分子の無針注入
BR0108962A (pt) 2000-03-03 2002-12-24 Valentis Inc Formulações de ácido nucléico para distribuição de genes e métodos de uso
WO2007149493A2 (fr) 2006-06-22 2007-12-27 Immugen Inc Correction d'une perte auditive
CA2677273A1 (fr) 2007-02-06 2008-08-14 Tai-June Yoo Traitement et prevention de maladies neurodegeneratives utilisant la therapie genetique
EP2383286A1 (fr) 2010-04-30 2011-11-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédés et compositions pour le traitement des maladies rétiniennes dégénératives
DE102010049036B4 (de) 2010-10-21 2021-11-18 Gramm medical healthcare GmbH Wässrige Lösung zum Spülen von Geweben oder Organen
US20150038557A1 (en) 2012-02-24 2015-02-05 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and compositions for treatment of retinal degenerative diseases
JP2019509997A (ja) 2016-02-17 2019-04-11 ザ チルドレンズ メディカル センター コーポレーション 神経血管形成疾患または障害の治療標的としてのｆｆａ１（ｇｐｒ４０）
CA3143071A1 (fr) * 2019-07-26 2021-02-04 Proqr Therapeutics Ii B.V. Compositions ophtalmiques comprenant des polymeres viscosifiants et des acides nucleiques

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4283393A (en) * 1979-03-13 1981-08-11 Merck & Co., Inc. Topical application of interferon inducers
IE66830B1 (en) * 1987-08-12 1996-02-07 Hem Res Inc Topically active compositions of double-stranded RNAs
IT1232318B (it) * 1989-09-07 1992-01-28 Crinos Industria Farmaco Composizioni ad uso topico contenenti acidi nucleici depolimerizzati per la cosmesi della pelle e del corpo.

Also Published As

Publication number Publication date
AU6714094A (en) 1994-11-21
WO1994024983A3 (fr) 1995-01-19
WO1994024983A2 (fr) 1994-11-10
EP0695186A1 (fr) 1996-02-07

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Legal Events

Date Code Title Description
FZDE Discontinued