CA2156397A1 - Rapamycin assay - Google Patents

Rapamycin assay

Info

Publication number
CA2156397A1
CA2156397A1 CA002156397A CA2156397A CA2156397A1 CA 2156397 A1 CA2156397 A1 CA 2156397A1 CA 002156397 A CA002156397 A CA 002156397A CA 2156397 A CA2156397 A CA 2156397A CA 2156397 A1 CA2156397 A1 CA 2156397A1
Authority
CA
Canada
Prior art keywords
rapamycin
assay
assay kits
rapamycin assay
immunosuppressant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002156397A
Other languages
French (fr)
Other versions
CA2156397C (en
Inventor
Valerie Quesniaux
Richard Sedrani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939307491A external-priority patent/GB9307491D0/en
Application filed by Individual filed Critical Individual
Publication of CA2156397A1 publication Critical patent/CA2156397A1/en
Application granted granted Critical
Publication of CA2156397C publication Critical patent/CA2156397C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1292—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Actinomyces; from Streptomyces (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them. Rapamycin has known pharmaceutical applications, in particular, as an immunosuppressant. The assay kits of the present invention can be used for monitoring blood levels of rapamycin.
CA002156397A 1993-04-08 1994-03-30 Rapamycin assay Expired - Lifetime CA2156397C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939307491A GB9307491D0 (en) 1993-04-08 1993-04-08 Organic compounds
GB9307491.2 1993-04-08
PCT/EP1994/001006 WO1994024304A1 (en) 1993-04-08 1994-03-30 Rapamycin assay

Publications (2)

Publication Number Publication Date
CA2156397A1 true CA2156397A1 (en) 1994-10-27
CA2156397C CA2156397C (en) 2007-05-15

Family

ID=38069000

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002156397A Expired - Lifetime CA2156397C (en) 1993-04-08 1994-03-30 Rapamycin assay

Country Status (1)

Country Link
CA (1) CA2156397C (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111693473A (en) * 2019-01-09 2020-09-22 北京九强生物技术股份有限公司 6-phosphoglucose dehydrogenase mutant and application thereof in preparing rapamycin detection reagent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111693473A (en) * 2019-01-09 2020-09-22 北京九强生物技术股份有限公司 6-phosphoglucose dehydrogenase mutant and application thereof in preparing rapamycin detection reagent

Also Published As

Publication number Publication date
CA2156397C (en) 2007-05-15

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20140331