CA2152387A1 - Synergistic anti-viral compositions - Google Patents

Synergistic anti-viral compositions

Info

Publication number
CA2152387A1
CA2152387A1 CA2152387A CA2152387A CA2152387A1 CA 2152387 A1 CA2152387 A1 CA 2152387A1 CA 2152387 A CA2152387 A CA 2152387A CA 2152387 A CA2152387 A CA 2152387A CA 2152387 A1 CA2152387 A1 CA 2152387A1
Authority
CA
Canada
Prior art keywords
viral
synergistic anti
viral compositions
neucleoside
analogue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2152387A
Other languages
French (fr)
Other versions
CA2152387C (en
Inventor
Michael Twist (Deceased)
Martin Sumner-Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allelix Biopharmaceuticals Inc
Original Assignee
Michael Twist (Deceased)
Martin Sumner-Smith
Allelix Biopharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michael Twist (Deceased), Martin Sumner-Smith, Allelix Biopharmaceuticals Inc. filed Critical Michael Twist (Deceased)
Publication of CA2152387A1 publication Critical patent/CA2152387A1/en
Application granted granted Critical
Publication of CA2152387C publication Critical patent/CA2152387C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

An anti-viral composition includes a synergistic combination of an anti-viral neucleoside analogue, which may inhibit a virus-specific enzyme, such as viral thymidine kinase and reverse transcriptase, an anti-viral oligopeptide compound having from 6 to 12 amino acid residues substantially all of which are D-arginine residues, and a pharmaceutically acceptable carrier. A method for treating a viral infection is also described.
CA002152387A 1992-12-22 1993-12-22 Synergistic anti-viral compositions Expired - Fee Related CA2152387C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99574292A 1992-12-22 1992-12-22
US07/995,742 1992-12-22

Publications (2)

Publication Number Publication Date
CA2152387A1 true CA2152387A1 (en) 1994-07-07
CA2152387C CA2152387C (en) 1998-10-27

Family

ID=25542161

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002152387A Expired - Fee Related CA2152387C (en) 1992-12-22 1993-12-22 Synergistic anti-viral compositions

Country Status (3)

Country Link
AU (1) AU5829994A (en)
CA (1) CA2152387C (en)
WO (1) WO1994014464A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0675731A1 (en) * 1993-10-22 1995-10-11 Allelix Biopharmaceuticals Inc. Treatment of cytomegalovirus infection
US6043268A (en) * 1994-06-29 2000-03-28 Hiroshi Maeda Agent for treatment of viral infections
JP2002502376A (en) 1997-05-21 2002-01-22 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ Compositions and methods for enhancing transport across biological membranes
US7229961B2 (en) 1999-08-24 2007-06-12 Cellgate, Inc. Compositions and methods for enhancing drug delivery across and into ocular tissues
US6669951B2 (en) 1999-08-24 2003-12-30 Cellgate, Inc. Compositions and methods for enhancing drug delivery across and into epithelial tissues
US6730293B1 (en) 1999-08-24 2004-05-04 Cellgate, Inc. Compositions and methods for treating inflammatory diseases of the skin
EP1210121A2 (en) 1999-08-24 2002-06-05 Cellgate Inc. Enhancing drug delivery across and into epithelial tissues using oligo arginine moieties

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2092075A1 (en) * 1990-10-24 1992-04-25 Martin Sumner-Smith Peptide-based inhibitors of hiv replication

Also Published As

Publication number Publication date
AU5829994A (en) 1994-07-19
WO1994014464A1 (en) 1994-07-07
CA2152387C (en) 1998-10-27

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed