CA2136087A1 - Sequence of human dopamine transporter cdna - Google Patents

Sequence of human dopamine transporter cdna

Info

Publication number
CA2136087A1
CA2136087A1 CA002136087A CA2136087A CA2136087A1 CA 2136087 A1 CA2136087 A1 CA 2136087A1 CA 002136087 A CA002136087 A CA 002136087A CA 2136087 A CA2136087 A CA 2136087A CA 2136087 A1 CA2136087 A1 CA 2136087A1
Authority
CA
Canada
Prior art keywords
hudat
dopamine transporter
sequence
human dopamine
transporter cdna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002136087A
Other languages
French (fr)
Other versions
CA2136087C (en
Inventor
George R. Uhl
David J. Vandenbergh
Antonio Persico
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Government
Original Assignee
George R. Uhl
David J. Vandenbergh
Antonio Persico
The Government Of The United States Of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by George R. Uhl, David J. Vandenbergh, Antonio Persico, The Government Of The United States Of America filed Critical George R. Uhl
Publication of CA2136087A1 publication Critical patent/CA2136087A1/en
Application granted granted Critical
Publication of CA2136087C publication Critical patent/CA2136087C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Abstract

The cloning and characterization of a human dopamine transporter (HUDAT) cDNA
is described. RFLP analysis is used to determine the distribution of HUDAT alleles in two ethnic backgrounds. The means by which the association between HUDAT alleles and behavioral disorders which have altered HUDAT expression as a basis for their etiology is discussed. Methods for evaluating the expression of HUDAT are described.
CA002136087A 1992-06-01 1993-06-01 Sequence of human dopamine transporter cdna Expired - Lifetime CA2136087C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88972392A 1992-06-01 1992-06-01
US07/889,723 1992-06-01
PCT/US1993/005179 WO1993024628A2 (en) 1992-06-01 1993-06-01 SEQUENCE OF HUMAN DOPAMINE TRANSPORTER cDNA

Publications (2)

Publication Number Publication Date
CA2136087A1 true CA2136087A1 (en) 1993-12-09
CA2136087C CA2136087C (en) 2004-11-30

Family

ID=25395672

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002136087A Expired - Lifetime CA2136087C (en) 1992-06-01 1993-06-01 Sequence of human dopamine transporter cdna

Country Status (4)

Country Link
EP (1) EP0644934A1 (en)
AU (1) AU686564B2 (en)
CA (1) CA2136087C (en)
WO (1) WO1993024628A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7385596A (en) * 1995-10-02 1997-04-28 Duke University Dopamine transporter knockout mice
WO2002094378A2 (en) * 2001-05-22 2002-11-28 Active Pass Pharmaceuticals, Inc. Increased functional activity and/or expression of abc transporters protects against the loss of dopamine neurons associated with parkinson's disease
GB2381525A (en) * 2001-11-01 2003-05-07 Tcs Cellworks Ltd Regulating gene expression

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312734A (en) * 1991-09-20 1994-05-17 The United States Of America As Represented By The Department Of Health And Human Services CDNA encoding a dopamine transporter
AU2919292A (en) * 1991-10-25 1993-05-21 State of Oregon acting by and through the The State Board of Higher Education on Behalf of the Oregon Health Sciences University, The A cdna clone encoding an expressible dopamine transporter

Also Published As

Publication number Publication date
WO1993024628A3 (en) 1994-02-03
EP0644934A1 (en) 1995-03-29
WO1993024628A2 (en) 1993-12-09
AU4597593A (en) 1993-12-30
CA2136087C (en) 2004-11-30
AU686564B2 (en) 1998-02-12

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Legal Events

Date Code Title Description
EEER Examination request