CA2110410A1 - Therapeutic Compositions for Osteoinduction - Google Patents

Therapeutic Compositions for Osteoinduction

Info

Publication number
CA2110410A1
CA2110410A1 CA2110410A CA2110410A CA2110410A1 CA 2110410 A1 CA2110410 A1 CA 2110410A1 CA 2110410 A CA2110410 A CA 2110410A CA 2110410 A CA2110410 A CA 2110410A CA 2110410 A1 CA2110410 A1 CA 2110410A1
Authority
CA
Canada
Prior art keywords
osteoinduction
therapeutic compositions
mammal
safe
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2110410A
Other languages
French (fr)
Other versions
CA2110410C (en
Inventor
Roger Lee Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2110410A1 publication Critical patent/CA2110410A1/en
Application granted granted Critical
Publication of CA2110410C publication Critical patent/CA2110410C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A method for generating new bone growth in a mammal comprising administering to the mammal a safe and effective amount of a Vitamin D compound in combination with a safe and effective amount of osteoinductive extract or at least one BMP
CA002110410A 1991-06-05 1992-05-26 Therapeutic compositions for osteoinduction Expired - Fee Related CA2110410C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US70962191A 1991-06-05 1991-06-05
US709,621 1991-06-05
US85611092A 1992-03-27 1992-03-27
US856,110 1992-03-27

Publications (2)

Publication Number Publication Date
CA2110410A1 true CA2110410A1 (en) 1992-12-10
CA2110410C CA2110410C (en) 1997-04-15

Family

ID=27108286

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002110410A Expired - Fee Related CA2110410C (en) 1991-06-05 1992-05-26 Therapeutic compositions for osteoinduction

Country Status (13)

Country Link
EP (1) EP0587751A1 (en)
JP (1) JPH06508140A (en)
AU (1) AU667815B2 (en)
BR (1) BR9206110A (en)
CA (1) CA2110410C (en)
CZ (1) CZ282231B6 (en)
IE (1) IE921812A1 (en)
NO (1) NO934381L (en)
NZ (1) NZ243018A (en)
PT (1) PT100567A (en)
RU (1) RU2107512C1 (en)
SK (1) SK136693A3 (en)
WO (1) WO1992021365A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056882B2 (en) 1991-03-11 2006-06-06 Curis, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
US5674844A (en) * 1991-03-11 1997-10-07 Creative Biomolecules, Inc. Treatment to prevent loss of and/or increase bone mass in metabolic bone diseases
DE69233559T2 (en) * 1991-08-30 2006-08-31 Curis, Inc., Cambridge OSTEOGENIC PROTEINS IN THE TREATMENT OF METABOLIC BONE DISEASES
US6071695A (en) * 1992-02-21 2000-06-06 Creative Biomolecules, Inc. Methods and products for identification of modulators of osteogenic protein-1 gene expression
DE69418865T2 (en) * 1993-03-29 2000-02-17 Zymogenetics, Inc. EAST BLAST GROWTH COMPOSITIONS CONTAINING PDGF AND VITAMIN-D
EP0804573A1 (en) * 1994-06-07 1997-11-05 Creative Biomolecules, Inc. Methods and compositions for modulating morphogenic protein expression
US7026292B1 (en) 1995-12-12 2006-04-11 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
US6048964A (en) * 1995-12-12 2000-04-11 Stryker Corporation Compositions and therapeutic methods using morphogenic proteins and stimulatory factors
US6492508B1 (en) 1996-06-03 2002-12-10 United States Surgical Corp. A Division Of Tyco Healthcare Group Nucleic acids encoding extracellular matrix proteins
ATE239514T1 (en) * 1997-02-07 2003-05-15 Stryker Corp MATRIXLESS OSTEOGENIC DEVICES AND IMPLANTS AND METHOD OF USE THEREOF
KR101072867B1 (en) * 2001-10-31 2011-10-17 유니버시티 오브 노스 텍사스 헬스 사이언스 센터 Bone morphogenic proteins (bmp), bmp receptors and bmp binding proteins and their use in the diagnosis and treatment of glaucoma
JP5444212B2 (en) * 2007-04-25 2014-03-19 シトクロマ インコーポレイテッド Method for treating vitamin D deficiency and deficiency
SG2014010680A (en) * 2009-02-12 2014-04-28 Stryker Corp Peripheral administration of proteins including tgf-beta superfamily members for treatment of systemic disorders and disease
CN102369017A (en) * 2009-02-12 2012-03-07 史赛克公司 Compositions and methods for minimally invasive systemic delivery of proteins comprising TGF-beta superfamily members
RU2595804C1 (en) * 2015-04-23 2016-08-27 Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский государственный технический университет имени Гагарина Ю.А." (СГТУ имени Гагарина Ю.А.) Composition for producing dental therapeutic film

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4833125A (en) * 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass

Also Published As

Publication number Publication date
NO934381D0 (en) 1993-12-02
IE921812A1 (en) 1992-12-16
SK136693A3 (en) 1994-10-05
NO934381L (en) 1994-01-31
NZ243018A (en) 1995-12-21
CZ282231B6 (en) 1997-06-11
AU667815B2 (en) 1996-04-18
CZ262493A3 (en) 1994-07-13
EP0587751A1 (en) 1994-03-23
CA2110410C (en) 1997-04-15
JPH06508140A (en) 1994-09-14
AU2145492A (en) 1993-01-08
WO1992021365A1 (en) 1992-12-10
BR9206110A (en) 1995-07-11
RU2107512C1 (en) 1998-03-27
PT100567A (en) 1994-01-31

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Legal Events

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