CA2110213A1 - Inhibition de la methyltransferase de l'adn a des fins therapeutiques - Google Patents
Inhibition de la methyltransferase de l'adn a des fins therapeutiquesInfo
- Publication number
- CA2110213A1 CA2110213A1 CA002110213A CA2110213A CA2110213A1 CA 2110213 A1 CA2110213 A1 CA 2110213A1 CA 002110213 A CA002110213 A CA 002110213A CA 2110213 A CA2110213 A CA 2110213A CA 2110213 A1 CA2110213 A1 CA 2110213A1
- Authority
- CA
- Canada
- Prior art keywords
- cells
- dna
- transfectants
- methylation
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
- C12N9/1007—Methyltransferases (general) (2.1.1.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002110213A CA2110213A1 (fr) | 1993-11-30 | 1993-11-30 | Inhibition de la methyltransferase de l'adn a des fins therapeutiques |
| DE69417918T DE69417918T2 (de) | 1993-11-30 | 1994-11-30 | Dna methyltransferase inhibierung |
| EP03012172A EP1352956A1 (fr) | 1993-11-30 | 1994-11-30 | Inhbition d' une méthyltransferase d' ADN |
| KR1019960702850A KR100392057B1 (ko) | 1993-11-30 | 1994-11-30 | 세포의 CpG 디뉴클레오티드 내의 시토신의 메틸화를 감소하는 방법 |
| EP98112207A EP0889122A3 (fr) | 1993-11-30 | 1994-11-30 | Inhibition de la methyltransferase de l' ADN |
| CA002177031A CA2177031A1 (fr) | 1993-11-30 | 1994-11-30 | Inhibition de la methyltransferase de l'adn |
| PCT/CA1994/000659 WO1995015373A2 (fr) | 1993-11-30 | 1994-11-30 | Inhibition de la methyltransferase de l'adn |
| AU10613/95A AU1061395A (en) | 1993-11-30 | 1994-11-30 | Inhibition of dna methyltransferase |
| EP95901306A EP0734436B1 (fr) | 1993-11-30 | 1994-11-30 | Inhibition de la methyltransferase de l'adn |
| JP7515312A JPH09506253A (ja) | 1993-11-30 | 1994-11-30 | Ｄｎａメチルトランスフェラーゼの阻害 |
| US08/652,425 US6184211B1 (en) | 1993-11-30 | 1994-11-30 | Inhibition of DNA methyltransferase |
| AT95901306T ATE178939T1 (de) | 1993-11-30 | 1994-11-30 | Dna methyltransferase inhibierung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002110213A CA2110213A1 (fr) | 1993-11-30 | 1993-11-30 | Inhibition de la methyltransferase de l'adn a des fins therapeutiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2110213A1 true CA2110213A1 (fr) | 1995-05-31 |
Family
ID=4152544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002110213A Abandoned CA2110213A1 (fr) | 1993-11-30 | 1993-11-30 | Inhibition de la methyltransferase de l'adn a des fins therapeutiques |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2110213A1 (fr) |
-
1993
- 1993-11-30 CA CA002110213A patent/CA2110213A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |