CA2106457A1 - Difluoromethylenandrostenone derivatives and process for their preparation - Google Patents

Difluoromethylenandrostenone derivatives and process for their preparation

Info

Publication number
CA2106457A1
CA2106457A1 CA002106457A CA2106457A CA2106457A1 CA 2106457 A1 CA2106457 A1 CA 2106457A1 CA 002106457 A CA002106457 A CA 002106457A CA 2106457 A CA2106457 A CA 2106457A CA 2106457 A1 CA2106457 A1 CA 2106457A1
Authority
CA
Canada
Prior art keywords
compound
formula
symbol
group
aromatase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002106457A
Other languages
English (en)
French (fr)
Inventor
Franco Buzzetti
Antonio Longo
Angelo Crugnola
Enrico Di Salle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2106457A1 publication Critical patent/CA2106457A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0014—Androstane derivatives substituted in position 17 alfa, not substituted in position 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0025—Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002106457A 1992-01-21 1993-01-18 Difluoromethylenandrostenone derivatives and process for their preparation Abandoned CA2106457A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929201224A GB9201224D0 (en) 1992-01-21 1992-01-21 Difluoromethylenandrostenone derivatives and process for their preparation
GB9201224.4 1992-01-21
PCT/EP1993/000105 WO1993014105A1 (en) 1992-01-21 1993-01-18 Difluoromethylenandrostenone derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
CA2106457A1 true CA2106457A1 (en) 1993-07-22

Family

ID=10708955

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002106457A Abandoned CA2106457A1 (en) 1992-01-21 1993-01-18 Difluoromethylenandrostenone derivatives and process for their preparation

Country Status (10)

Country Link
JP (1) JPH06507181A (fi)
AU (1) AU3351593A (fi)
CA (1) CA2106457A1 (fi)
FI (1) FI934093A (fi)
GB (1) GB9201224D0 (fi)
HU (1) HUT64968A (fi)
IL (1) IL104204A0 (fi)
MX (1) MX9300244A (fi)
WO (1) WO1993014105A1 (fi)
ZA (1) ZA9335B (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9313420D0 (en) * 1993-06-29 1993-08-11 Erba Carlo Spa Fluorinated 6-methylenandrosta-1,4-dien-3-one-derivatives and process for their preparations
DE19633349A1 (de) * 1996-08-19 1998-02-26 Sigma Tau Ind Farmaceuti Neue 6-Hydroxy- und 6-Oxo-androstan-Derivate, die auf das kardiovaskuläre System wirken und pharmazeutische Zusammensetzungen, die diese enthalten

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones
GB8622330D0 (en) * 1986-09-17 1986-10-22 Erba Farmitalia 4-substituted 6-alkylidenandrostene-3,17-dione derivatives
GB8721383D0 (en) * 1987-09-11 1987-10-21 Erba Farmitalia Preparation of methylene derivatives
GB8721384D0 (en) * 1987-09-11 1987-10-21 Erba Farmitalia 17-substituted andro-sta-1 4-dien-3-one derivatives
GB8801697D0 (en) * 1988-01-26 1988-02-24 Erba Farmitalia Improvements in synthesis of 6-methylene derivatives of androsta-1 4-diene-3 17-dione

Also Published As

Publication number Publication date
FI934093A0 (fi) 1993-09-17
HU9302649D0 (en) 1993-12-28
ZA9335B (en) 1993-08-05
JPH06507181A (ja) 1994-08-11
GB9201224D0 (en) 1992-03-11
IL104204A0 (en) 1993-05-13
HUT64968A (en) 1994-03-28
AU3351593A (en) 1993-08-03
FI934093A (fi) 1993-09-17
WO1993014105A1 (en) 1993-07-22
MX9300244A (es) 1993-07-01

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Legal Events

Date Code Title Description
FZDE Discontinued