CA2088360A1 - Analyse quantitative et surveillance de la structure d'une proteine par chromatographie par soustraction - Google Patents
Analyse quantitative et surveillance de la structure d'une proteine par chromatographie par soustractionInfo
- Publication number
- CA2088360A1 CA2088360A1 CA002088360A CA2088360A CA2088360A1 CA 2088360 A1 CA2088360 A1 CA 2088360A1 CA 002088360 A CA002088360 A CA 002088360A CA 2088360 A CA2088360 A CA 2088360A CA 2088360 A1 CA2088360 A1 CA 2088360A1
- Authority
- CA
- Canada
- Prior art keywords
- matrix
- concentration
- protein
- sample
- binding sites
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N2030/626—Detectors specially adapted therefor calibration, baseline
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56612190A | 1990-08-10 | 1990-08-10 | |
US566,121 | 1990-08-10 | ||
PCT/US1991/005544 WO1992002815A2 (fr) | 1990-08-10 | 1991-08-01 | Surveillance et analyse quantitative de la structure des proteines par chromatographie soustractive |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2088360A1 true CA2088360A1 (fr) | 1992-02-11 |
Family
ID=24261583
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002088360A Abandoned CA2088360A1 (fr) | 1990-08-10 | 1991-08-01 | Analyse quantitative et surveillance de la structure d'une proteine par chromatographie par soustraction |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0548178A1 (fr) |
JP (1) | JPH06500396A (fr) |
AU (1) | AU654503B2 (fr) |
CA (1) | CA2088360A1 (fr) |
WO (1) | WO1992002815A2 (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU647929B2 (en) * | 1991-03-28 | 1994-03-31 | Perseptive Biosystems, Inc. | On-line product identification in a chromatography effluent by subtraction |
US6613575B1 (en) | 1998-03-27 | 2003-09-02 | Ole Hindsgaul | Methods for screening compound libraries |
US6720190B1 (en) | 1998-03-27 | 2004-04-13 | Ole Hindsgaul | Methods for screening compound libraries |
US6054047A (en) | 1998-03-27 | 2000-04-25 | Synsorb Biotech, Inc. | Apparatus for screening compound libraries |
CA2240325A1 (fr) | 1998-03-27 | 1998-11-14 | Synsorb Biotech, Inc. | Methodes de criblage de banques de constituants |
DE19945351C2 (de) | 1999-09-22 | 2002-04-18 | Lohmann Therapie Syst Lts | Verfahren zum Auffinden und zur Isolierung pharmakologisch wirksamer Verbindungen aus Substanzgemischen |
CN102472731B (zh) * | 2009-06-26 | 2016-01-13 | 通用电气健康护理生物科学股份公司 | 色谱系统中的方法 |
EP3863763A4 (fr) * | 2018-10-09 | 2022-10-19 | C Technologies, Inc. | Système de commande de masse pour chromatographie |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4204424A (en) * | 1979-01-08 | 1980-05-27 | Phillips Petroleum Company | Chromatographic analyzer detector gain adjustment |
JPS56114761A (en) * | 1980-02-14 | 1981-09-09 | Shinotesuto Kenkyusho:Kk | Fractional determination method of zinc in fresh blood serum by affinity chromatography |
EP0141259B1 (fr) * | 1981-03-09 | 1989-06-07 | Environmental Sciences Associates, Inc. | Améliorations dans la chromatograhie liquide |
JPS58216954A (ja) * | 1982-06-11 | 1983-12-16 | Shimadzu Corp | 低温高速液体クロマトグラフイ |
JPS5984828A (ja) * | 1982-11-08 | 1984-05-16 | Suntory Ltd | 安定化免疫複合体およびその利用方法 |
IT1150598B (it) * | 1982-12-14 | 1986-12-17 | Ines Bianchi | Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita' |
JPS59143958A (ja) * | 1983-02-07 | 1984-08-17 | Sekisui Chem Co Ltd | フイブロネクチンの定量法 |
JPS63236964A (ja) * | 1987-03-26 | 1988-10-03 | Ube Ind Ltd | 糖尿病の診断法 |
WO1990006516A1 (fr) * | 1988-12-05 | 1990-06-14 | Primus Corporation | Procede de determination d'especes proteiques glucosees |
-
1991
- 1991-08-01 JP JP51561891A patent/JPH06500396A/ja active Pending
- 1991-08-01 CA CA002088360A patent/CA2088360A1/fr not_active Abandoned
- 1991-08-01 AU AU85306/91A patent/AU654503B2/en not_active Ceased
- 1991-08-01 WO PCT/US1991/005544 patent/WO1992002815A2/fr not_active Application Discontinuation
- 1991-08-01 EP EP19910916341 patent/EP0548178A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JPH06500396A (ja) | 1994-01-13 |
EP0548178A1 (fr) | 1993-06-30 |
WO1992002815A2 (fr) | 1992-02-20 |
AU654503B2 (en) | 1994-11-10 |
WO1992002815A3 (fr) | 1992-04-30 |
AU8530691A (en) | 1992-03-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |