CA2065294A1 - Oligonucleotides anti-sens du proto-oncogene c-abl - Google Patents
Oligonucleotides anti-sens du proto-oncogene c-ablInfo
- Publication number
- CA2065294A1 CA2065294A1 CA002065294A CA2065294A CA2065294A1 CA 2065294 A1 CA2065294 A1 CA 2065294A1 CA 002065294 A CA002065294 A CA 002065294A CA 2065294 A CA2065294 A CA 2065294A CA 2065294 A1 CA2065294 A1 CA 2065294A1
- Authority
- CA
- Canada
- Prior art keywords
- abl
- gca gat
- tcc agg
- cag gca
- gat ctc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40238389A | 1989-09-01 | 1989-09-01 | |
US402,383 | 1989-09-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2065294A1 true CA2065294A1 (fr) | 1991-03-02 |
Family
ID=23591651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002065294A Abandoned CA2065294A1 (fr) | 1989-09-01 | 1990-08-29 | Oligonucleotides anti-sens du proto-oncogene c-abl |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0489846A4 (fr) |
JP (1) | JPH05500217A (fr) |
AU (1) | AU646643B2 (fr) |
CA (1) | CA2065294A1 (fr) |
WO (1) | WO1991003260A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5087617A (en) * | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
WO1993008845A1 (fr) * | 1991-11-08 | 1993-05-13 | Massachusetts Institute Of Technology | Traitement par application localisee d'oligonucleotides |
WO1994010302A1 (fr) * | 1992-10-29 | 1994-05-11 | Boehringer Mannheim Gmbh | Vecteur amplifiable agissant a l'encontre de la replication du vih |
WO1994013793A1 (fr) * | 1992-12-04 | 1994-06-23 | Apollon, Inc. | Composes et methodes de traitement des leucemies |
JPH09503381A (ja) * | 1993-07-09 | 1997-04-08 | ジ・インスティテュート・オブ・キャンサー・リサーチ | プロテインチロシンキナーゼ及びそのリガンド |
WO1997008184A1 (fr) * | 1995-08-30 | 1997-03-06 | Arch Development Corporation | Procedes et compositions comprenant des agents alterant l'adn et des inhibiteurs ou des activateurs de la tyrosine kinase |
JP2003524637A (ja) * | 1999-12-23 | 2003-08-19 | エクシコン エ/エス | Lna修飾オリゴヌクレオチドの治療上の使用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ209840A (en) * | 1983-10-17 | 1988-11-29 | Kaji Akira | A method of inhibiting viral propagation by hybridising dna with the viral rna thus blocking its action |
US4806463A (en) * | 1986-05-23 | 1989-02-21 | Worcester Foundation For Experimental Biology | Inhibition of HTLV-III by exogenous oligonucleotides |
DE3744785A1 (de) * | 1987-12-11 | 1989-08-17 | Theurer Karl Eugen | Verwendung von ruecklaeufigen spiegelbildlichen anti-sense-nucleinsaeuren gegen krebserkrankungen |
-
1990
- 1990-08-29 EP EP19900913911 patent/EP0489846A4/en not_active Withdrawn
- 1990-08-29 JP JP2513022A patent/JPH05500217A/ja active Pending
- 1990-08-29 AU AU64107/90A patent/AU646643B2/en not_active Expired - Fee Related
- 1990-08-29 CA CA002065294A patent/CA2065294A1/fr not_active Abandoned
- 1990-08-29 WO PCT/US1990/004961 patent/WO1991003260A1/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1991003260A1 (fr) | 1991-03-21 |
AU646643B2 (en) | 1994-03-03 |
EP0489846A1 (fr) | 1992-06-17 |
JPH05500217A (ja) | 1993-01-21 |
EP0489846A4 (en) | 1992-06-24 |
AU6410790A (en) | 1991-04-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |