CA2061579C - Regulateur de la conductance transmembranaire dans la fibrose kystique - Google Patents

Regulateur de la conductance transmembranaire dans la fibrose kystique Download PDF

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Publication number
CA2061579C
CA2061579C CA 2061579 CA2061579A CA2061579C CA 2061579 C CA2061579 C CA 2061579C CA 2061579 CA2061579 CA 2061579 CA 2061579 A CA2061579 A CA 2061579A CA 2061579 C CA2061579 C CA 2061579C
Authority
CA
Canada
Prior art keywords
protein
cftr
channel
cells
purified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA 2061579
Other languages
English (en)
Other versions
CA2061579A1 (fr
Inventor
John R. Riordan
Christine E. Bear
Mohabir Ramjeesingh
Canhui Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HSC Research and Development LP
Original Assignee
HSC Research and Development LP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HSC Research and Development LP filed Critical HSC Research and Development LP
Priority to CA 2061579 priority Critical patent/CA2061579C/fr
Priority to PCT/CA1993/000065 priority patent/WO1993017040A2/fr
Priority to US08/290,935 priority patent/US5543399A/en
Priority to AU34891/93A priority patent/AU3489193A/en
Publication of CA2061579A1 publication Critical patent/CA2061579A1/fr
Application granted granted Critical
Publication of CA2061579C publication Critical patent/CA2061579C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712—Cystic fibrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA 2061579 1989-08-22 1992-02-20 Regulateur de la conductance transmembranaire dans la fibrose kystique Expired - Fee Related CA2061579C (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA 2061579 CA2061579C (fr) 1992-02-20 1992-02-20 Regulateur de la conductance transmembranaire dans la fibrose kystique
PCT/CA1993/000065 WO1993017040A2 (fr) 1992-02-20 1993-02-17 Proteine regulatrice de la conductance transmembranaire fibrokystique (cftr)
US08/290,935 US5543399A (en) 1989-08-22 1993-02-17 Cystic fibrosis transmembrane conductance regulator (CFTR) protein
AU34891/93A AU3489193A (en) 1992-02-20 1993-02-17 Cystic fibrosis transmembrane conductance regulator (CFTR) protein

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2061579 CA2061579C (fr) 1992-02-20 1992-02-20 Regulateur de la conductance transmembranaire dans la fibrose kystique

Publications (2)

Publication Number Publication Date
CA2061579A1 CA2061579A1 (fr) 1993-08-21
CA2061579C true CA2061579C (fr) 2008-07-22

Family

ID=4149304

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2061579 Expired - Fee Related CA2061579C (fr) 1989-08-22 1992-02-20 Regulateur de la conductance transmembranaire dans la fibrose kystique

Country Status (3)

Country Link
AU (1) AU3489193A (fr)
CA (1) CA2061579C (fr)
WO (1) WO1993017040A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063913A (en) * 1989-08-22 2000-05-16 Hsc Research And Development Limited Partnership Stable heterologous propagation CFTR protein variant cDNA
US6984487B1 (en) 1989-08-22 2006-01-10 Hsc Research Development Corporation Cystic fibrosis gene
WO1991010734A1 (fr) * 1990-01-12 1991-07-25 Hsc Research Development Corporation Introns et exons du gene de la fibrose cystique et mutations a differentes positions du gene
US6245735B1 (en) 1996-07-29 2001-06-12 The Brigham And Women's Hospital, Inc. Methods and products for treating pseudomonas infection
US6962813B2 (en) 2001-05-21 2005-11-08 The Brigham And Women's Hospital, Inc. P. aeruginosa mucoid exopolysaccharide specific binding peptides
US7119172B2 (en) 2001-05-21 2006-10-10 The Brigham And Women's Hospital, Inc. P. aeruginosa mucoid exopolysaccharide specific binding peptides
GB0606190D0 (en) 2006-03-28 2006-05-10 Isis Innovation Construct

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2037478A1 (fr) * 1990-03-05 1991-09-06 Richard Gregory Methodes de diagnostic et de traitement faisant appel a un regulateur membranaire de la fibrose kystique

Also Published As

Publication number Publication date
CA2061579A1 (fr) 1993-08-21
WO1993017040A3 (fr) 1993-09-30
AU3489193A (en) 1993-09-13
WO1993017040A2 (fr) 1993-09-02

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