CA2061197A1 - Salicyloyl carnitine and process for its preparation - Google Patents

Salicyloyl carnitine and process for its preparation

Info

Publication number
CA2061197A1
CA2061197A1 CA 2061197 CA2061197A CA2061197A1 CA 2061197 A1 CA2061197 A1 CA 2061197A1 CA 2061197 CA2061197 CA 2061197 CA 2061197 A CA2061197 A CA 2061197A CA 2061197 A1 CA2061197 A1 CA 2061197A1
Authority
CA
Canada
Prior art keywords
carnitine
salicyloyl
preparation
vis
trimethylarnmonio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2061197
Other languages
French (fr)
Other versions
CA2061197C (en
Inventor
Thomas Meul
Jacques Deshusses
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Priority to CA 2061197 priority Critical patent/CA2061197C/en
Publication of CA2061197A1 publication Critical patent/CA2061197A1/en
Application granted granted Critical
Publication of CA2061197C publication Critical patent/CA2061197C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel 3-(2-hydroxybenzoyloxy)-4-(trimethylarnmonio)-butyric acid betaine and its pharmaceutically acceptable salts are disclosed. The compounds are distinguished by high water solubility, minimum toxicity, and good gastric tolerance vis-a-vis acetylsalicylic acid and can be prepared from carnitine hydrochloride and o-methoxybenzoyl chloride.
CA 2061197 1992-02-13 1992-02-13 Salicyloyl carnitine and process for its preparation Expired - Fee Related CA2061197C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA 2061197 CA2061197C (en) 1992-02-13 1992-02-13 Salicyloyl carnitine and process for its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2061197 CA2061197C (en) 1992-02-13 1992-02-13 Salicyloyl carnitine and process for its preparation

Publications (2)

Publication Number Publication Date
CA2061197A1 true CA2061197A1 (en) 1993-08-14
CA2061197C CA2061197C (en) 2002-04-30

Family

ID=4149253

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2061197 Expired - Fee Related CA2061197C (en) 1992-02-13 1992-02-13 Salicyloyl carnitine and process for its preparation

Country Status (1)

Country Link
CA (1) CA2061197C (en)

Also Published As

Publication number Publication date
CA2061197C (en) 2002-04-30

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed