CA2040920A1 - Capillary inoculator and assembly for inoculating multiple test sites and method of inoculation test sites therewith - Google Patents

Capillary inoculator and assembly for inoculating multiple test sites and method of inoculation test sites therewith

Info

Publication number
CA2040920A1
CA2040920A1 CA2040920A CA2040920A CA2040920A1 CA 2040920 A1 CA2040920 A1 CA 2040920A1 CA 2040920 A CA2040920 A CA 2040920A CA 2040920 A CA2040920 A CA 2040920A CA 2040920 A1 CA2040920 A1 CA 2040920A1
Authority
CA
Canada
Prior art keywords
test sites
inoculum
inoculator
capillaries
capillary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2040920A
Other languages
French (fr)
Other versions
CA2040920C (en
Inventor
Bradley Scott Thomas
Gregory Tice
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of CA2040920A1 publication Critical patent/CA2040920A1/en
Application granted granted Critical
Publication of CA2040920C publication Critical patent/CA2040920C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Devices For Use In Laboratory Experiments (AREA)

Abstract

A capillary inoculator assembly is provided for inoculating multiple test sites with small, precise volumes of inoculum. The inoculator employed in the assembly includes a trough-shaped carrier and one or more rows of capillaries extending therethrough. The capillaries extend through one or more rows of projections which form the lower part of the carrier. They are completely filled by capillary action, and the inoculum is retained therein by forces of adhesion and surface tension. A test device may be employed in conjunction with the capillary inoculator and includes discrete test sites which are aligned with the ends of the respective projections. Each of the test sites may be provided with an absorbent material such as a cellulose disk. A dry reagent may be deposited upon each disk so that the inoculum may be analyzed by testing equipment or by visual observation. A method is provided which includes the steps of filling the capillaries, aligning the capillaries with the test sites within the test device, and depositing the liquid inoculum on the respective test sites through wicking action or other procedures. A method is also disclosed for providing a plurality of discrete, liquid samples having small, precise volumes from a quantity of liquid which may be of indeterminate volume.
CA002040920A 1990-05-29 1991-04-22 Capillary inoculator and assembly for inoculating multiple test sites and method of inoculation test sites therewith Expired - Fee Related CA2040920C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52980290A 1990-05-29 1990-05-29
US529,802 1990-05-29

Publications (2)

Publication Number Publication Date
CA2040920A1 true CA2040920A1 (en) 1991-11-30
CA2040920C CA2040920C (en) 1995-05-23

Family

ID=24111290

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002040920A Expired - Fee Related CA2040920C (en) 1990-05-29 1991-04-22 Capillary inoculator and assembly for inoculating multiple test sites and method of inoculation test sites therewith

Country Status (11)

Country Link
EP (1) EP0459093B1 (en)
JP (1) JPH0867B2 (en)
AT (1) ATE138412T1 (en)
AU (1) AU646242B2 (en)
CA (1) CA2040920C (en)
DE (1) DE69119647T2 (en)
FI (1) FI101324B (en)
IE (1) IE75386B1 (en)
MY (1) MY109607A (en)
NO (1) NO911083L (en)
NZ (1) NZ237521A (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5895761A (en) * 1993-07-21 1999-04-20 Clinical Diagnostic Systems, Inc. Surface area liquid transfer method and related apparatus
DK0635712T3 (en) * 1993-07-21 1998-09-14 Johnson & Johnson Clin Diag Process for pre-processing diagnostic test elements
US5955352A (en) * 1994-12-22 1999-09-21 Showa Yakuhin Kako Co., Ltd. Instruments for chemical and microbiological tests
EP0795600A4 (en) * 1994-12-22 1998-12-09 Showa Pharm Chem Ind Device for chemical and microbiological tests
EP0958379A1 (en) * 1996-12-23 1999-11-24 bioMerieux Vitek, Inc. Air matrix material for chemical reactions
US6696286B1 (en) 1997-04-09 2004-02-24 3M Innovative Properties Company Method and devices for detecting and enumerating microorganisms
US6391578B2 (en) 1997-04-09 2002-05-21 3M Innovative Properties Company Method and devices for partitioning biological sample liquids into microvolumes
CA2307123C (en) * 1997-10-27 2007-04-24 Idexx Laboratories, Inc. Device and methods for determination of analyte in a solution
US6566051B1 (en) 1999-01-15 2003-05-20 Medtox Scientific, Inc. Lateral flow test strip
US6416642B1 (en) * 1999-01-21 2002-07-09 Caliper Technologies Corp. Method and apparatus for continuous liquid flow in microscale channels using pressure injection, wicking, and electrokinetic injection
US6174699B1 (en) 1999-03-09 2001-01-16 3M Innovative Properties Company Disc assay device with inoculation pad and methods of use
JP4566509B2 (en) * 2001-12-28 2010-10-20 株式会社エンプラス Plastic plate and plastic plate assembly
CN100595280C (en) * 2003-03-10 2010-03-24 约翰霍普金斯大学 Method and apparatus for environmental monitoring and bioprospecting
JP5698900B2 (en) * 2009-03-19 2015-04-08 テルモ株式会社 Cell culture transfer device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552128A (en) * 1975-06-28 1979-09-05 Square D Co Computer based control systems including a protection circuit
GB1572596A (en) * 1976-12-06 1980-07-30 Opto Electronic Displays Ltd Apparatus and method for innoculation
DE3407849A1 (en) * 1984-02-29 1985-08-29 Alois 3201 Algermissen Höft METHOD AND DEVICE FOR SIMULTANEOUSLY APPLYING A VARIETY OF LIQUID SAMPLES TO A SLIDE

Also Published As

Publication number Publication date
ATE138412T1 (en) 1996-06-15
IE75386B1 (en) 1997-09-10
EP0459093A2 (en) 1991-12-04
NO911083D0 (en) 1991-03-19
FI912558A0 (en) 1991-05-28
NZ237521A (en) 1994-03-25
IE910931A1 (en) 1991-12-04
EP0459093A3 (en) 1992-12-02
DE69119647D1 (en) 1996-06-27
FI101324B1 (en) 1998-05-29
EP0459093B1 (en) 1996-05-22
FI912558A (en) 1991-11-30
FI101324B (en) 1998-05-29
MY109607A (en) 1997-03-31
DE69119647T2 (en) 1996-12-05
AU7280391A (en) 1991-12-05
JPH04228062A (en) 1992-08-18
CA2040920C (en) 1995-05-23
JPH0867B2 (en) 1996-01-10
NO911083L (en) 1991-12-02
AU646242B2 (en) 1994-02-17

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed