CA2037783A1 - Rebeccamycin analogs by tryptophan analogs feeding - Google Patents

Rebeccamycin analogs by tryptophan analogs feeding

Info

Publication number
CA2037783A1
CA2037783A1 CA2037783A CA2037783A CA2037783A1 CA 2037783 A1 CA2037783 A1 CA 2037783A1 CA 2037783 A CA2037783 A CA 2037783A CA 2037783 A CA2037783 A CA 2037783A CA 2037783 A1 CA2037783 A1 CA 2037783A1
Authority
CA
Canada
Prior art keywords
analogs
rebeccamycin
feeding
tryptophan
results
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2037783A
Other languages
French (fr)
Other versions
CA2037783C (en
Inventor
Kin Sing Lam
Daniel R. Schroeder
Jacqueline Mattei
Salvatore Forenza
James A. Matson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CA2037783A1 publication Critical patent/CA2037783A1/en
Application granted granted Critical
Publication of CA2037783C publication Critical patent/CA2037783C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin analogs having advantageous antitumor properties.
CA002037783A 1990-03-06 1991-03-05 Rebeccamycin analogs by tryptophan analogs feeding Expired - Fee Related CA2037783C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48943090A 1990-03-06 1990-03-06
US489,430 1990-03-06

Publications (2)

Publication Number Publication Date
CA2037783A1 true CA2037783A1 (en) 1991-09-07
CA2037783C CA2037783C (en) 1995-10-17

Family

ID=23943825

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002037783A Expired - Fee Related CA2037783C (en) 1990-03-06 1991-03-05 Rebeccamycin analogs by tryptophan analogs feeding

Country Status (3)

Country Link
CA (1) CA2037783C (en)
SK (1) SK278338B6 (en)
ZA (1) ZA911613B (en)

Also Published As

Publication number Publication date
SK278338B6 (en) 1996-12-04
ZA911613B (en) 1991-11-27
CA2037783C (en) 1995-10-17

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed