CA2012661A1 - Thienylpiperazines, process for the Preparation Thereof, the Use Thereof, and Pharmaceuticals Containing These and the Preparation Thereof - Google Patents

Thienylpiperazines, process for the Preparation Thereof, the Use Thereof, and Pharmaceuticals Containing These and the Preparation Thereof

Info

Publication number
CA2012661A1
CA2012661A1 CA2012661A CA2012661A CA2012661A1 CA 2012661 A1 CA2012661 A1 CA 2012661A1 CA 2012661 A CA2012661 A CA 2012661A CA 2012661 A CA2012661 A CA 2012661A CA 2012661 A1 CA2012661 A1 CA 2012661A1
Authority
CA
Canada
Prior art keywords
preparation
thienylpiperazines
pharmaceuticals containing
double
denotes hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2012661A
Other languages
French (fr)
Other versions
CA2012661C (en
Inventor
Karl Schonafinger
Rudi Beyerle
Ursula Schindler
Bernd Jablonka
Jeffery Troke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2012661A1 publication Critical patent/CA2012661A1/en
Application granted granted Critical
Publication of CA2012661C publication Critical patent/CA2012661C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

The present invention relates to thienylpiperazines of the general formula I <IMAGE> (I) in which R1 denotes hydrogen or double-bonded oxygen and R2 denotes hydrogen or double-bonded oxygen, with R1 and R2 not both having the same meaning, as well as the pharmaceutically tolerated salts thereof, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof.
CA002012661A 1989-03-22 1990-03-21 Thienylpiperazines, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof Expired - Lifetime CA2012661C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3909379A DE3909379A1 (en) 1989-03-22 1989-03-22 THIENYLPIPERAZINE, METHOD FOR THE PRODUCTION THEREOF, THE USE THEREOF AND THE MEDICAMENTS CONTAINING THEIR AND THEIR MANUFACTURE
DEP3909379.4 1989-03-22

Publications (2)

Publication Number Publication Date
CA2012661A1 true CA2012661A1 (en) 1990-09-22
CA2012661C CA2012661C (en) 2000-08-08

Family

ID=6376934

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002012661A Expired - Lifetime CA2012661C (en) 1989-03-22 1990-03-21 Thienylpiperazines, process for the preparation thereof, the use thereof, and pharmaceuticals containing these and the preparation thereof

Country Status (11)

Country Link
US (1) US4987134A (en)
EP (1) EP0388750B1 (en)
JP (1) JP2981251B2 (en)
KR (1) KR0148124B1 (en)
AT (1) ATE100807T1 (en)
CA (1) CA2012661C (en)
DD (1) DD292912A5 (en)
DE (2) DE3909379A1 (en)
HU (1) HUT58085A (en)
PT (1) PT93532A (en)
ZA (1) ZA902167B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101511823B (en) 2006-08-04 2014-07-30 麦那思制药（加拿大）有限公司 Multifunctional bioactive compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2528843A2 (en) * 1981-08-11 1983-12-23 Rhone Poulenc Sante NOVEL DERIVATIVES OF DITHIOLE-1,2 YLIDENE-3 AMMONIUM, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THE SAME
DE3132882A1 (en) * 1981-08-20 1983-03-03 Cassella Ag, 6000 Frankfurt NEW PIPERAZINONE, THEIR PRODUCTION AND USE
DE3329028A1 (en) * 1983-08-11 1985-02-28 Cassella Ag, 6000 Frankfurt Substituted (2-amino-2-imidazolin-1-yl)acetic acid derivatives, process for their preparation, their use and pharmaceutical preparations containing them
GB8427735D0 (en) * 1984-11-02 1984-12-12 Fujisawa Pharmaceutical Co Piperazine compound
DE3817198A1 (en) * 1988-05-20 1989-11-30 Cassella Ag THIENYL PIPERAZINONE, THEIR PREPARATION AND USE

Also Published As

Publication number Publication date
CA2012661C (en) 2000-08-08
DE59004377D1 (en) 1994-03-10
KR0148124B1 (en) 1998-08-17
DE3909379A1 (en) 1990-09-27
HUT58085A (en) 1992-01-28
EP0388750B1 (en) 1994-01-26
EP0388750A1 (en) 1990-09-26
HU901631D0 (en) 1990-06-28
KR900014372A (en) 1990-10-23
JP2981251B2 (en) 1999-11-22
DD292912A5 (en) 1991-08-14
PT93532A (en) 1990-11-07
ATE100807T1 (en) 1994-02-15
JPH02273674A (en) 1990-11-08
US4987134A (en) 1991-01-22
ZA902167B (en) 1990-12-28

Similar Documents

Publication Publication Date Title
AU578947B2 (en) Pyridazinones,preparation process thereof and utilization thereof, drugs containing pyridazinones
AU2125192A (en) New naphthylethlylureas and naphthylethylthioureas, process for the preparation thereof, and pharmaceutical compositions containing them
MY121192A (en) New compounds.
AU669122B2 (en) New pyrazine derivatives, their preparation and their use
AU3923789A (en) Diorganopolysiloxane derivatives, their preparation and their use
TW248559B (en)
NZ227990A (en) Cephemcarboxylic acid esters; pharmaceutical compositions and processes for preparation
AU3455093A (en) New adenosine derivatives, preparation methods and pharmaceutical compositions containing them
TW367326B (en) Pyrimidine derivative, process for the preparation thereof and a pharmaceutical composition containing same
ES2000907A6 (en) 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same.
CA2012661A1 (en) Thienylpiperazines, process for the Preparation Thereof, the Use Thereof, and Pharmaceuticals Containing These and the Preparation Thereof
ES8800156A1 (en) 3-Pyridylmethylnaphthyl derivatives, process for their preparation and their use as medicaments.
CA2119661A1 (en) New n-benzylpiperazine compounds, their preparation process and pharmaceutical compositions containing them
PT75385A (en) Process for the preparation of aminoglycosides derivatives and of compositions containing these derivatives
AU5522794A (en) New angiopeptin cyclopeptide compounds, process for the preparation thereof, and pharmaceutical compositios containing them
CA2012313A1 (en) Thienylacetic Acid Derivatives, Process for the Preparation Thereof, the Use Thereof, and Pharmaceuticals Containing These and the Preparation Thereof
ES8606272A1 (en) Carboxyalkyl dipeptide derivatives, process for their preparation, agents containing them, and their use.
AU2601088A (en) Hypoglycaemic peptides
AU579997B2 (en) Iminosulphonamides and processes for the manufacture thereof, pharmaceutical preparations containing such compounds, and their use
ES2000283A6 (en) Cycloaliphatic ketoamines.

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry