CA2009670C - Wound dressing - Google Patents
Wound dressingInfo
- Publication number
- CA2009670C CA2009670C CA 2009670 CA2009670A CA2009670C CA 2009670 C CA2009670 C CA 2009670C CA 2009670 CA2009670 CA 2009670 CA 2009670 A CA2009670 A CA 2009670A CA 2009670 C CA2009670 C CA 2009670C
- Authority
- CA
- Canada
- Prior art keywords
- wound
- wound dressing
- dressing
- magnesium sulfate
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Abstract
The present invention relates to a sterile dressing suitable for absorption and adsorption of exudate, transudate, bacteria, pus and necrotic tissue resulting from infected wounds and ulcers. Anhydrous magnesium sulfate is used as a disinfecting agent. The disinfecting composition also comprises a water-miscible base, and the said composition is impregnated in an absorbing material. Both cleaning and disinfection of the wound are accomplished in a single step operation.
Description
TITLE OF THE lNV~N'l ION: WOUND DRESSING 2 ~ 0 9 6 7 0 PRIOR ART
It is common practice to apply a fluid antiseptic on wounds, cuts, lacerations, burns and skin infections. In recent years, wound dressings for use on superficial burns, cuts and abrasions have been developed, providing a clear plastic film over the affected area.
These plastic wound dressings or "plastic bandages" are usually solutions of an acrylic or methacrylic co-polymer dissolved in a volatile non-aqueous organic solvent of low boiling point, such as ethyl acetate, acetone, ethyl alcohol or methylene chloride or mixtures thereof.
These bandages, however, have no antibacterial activity, and should therefore only be applied after thorough disinfection of the skin. A
most serious drawback of these liquid bandages is that the non-aqueous solvent containing the active ingredient(s) can cause considerable pain, if applied to open wounds, cuts and abrasions. Also, for good adherence, such liquid bandages can only be applied to perfectly dry skin. This makes them less suitable where the skin is contaminated by body fluids such as blood, perspiration or pus which is a situation frequently encountered with open wounds.
2no~670 Open wounds, cuts and abrasions can become threatening if they are not taken care of within a short period of time. Lack to do so can lead to dangerous infections which may require much more expensive treatment, such as the administration of antibiotics, steroids or enzymes, in order to control and eliminate the infection. Instant treatment and disinfection of open wound is therefore critical.
It would be highly desirable to have a wound dressing capable of cleaning up a wound by absorbing all exudate and transudate, removing undesirable necrotic tissue, pus and bacteria, and disinfecting the wound and the surrounding area. It would also be desirable that such dressing can promote granulation and healing of the wound in a single application.
SUMMARY OF THE lNv~:N-LlON:
In accordance with the present invention, there is now provided a sterile wound dressing suitable for cleaning and disinfecting a wound and its surrounding area, promoting granulation and favoring therefore the healing of the wound, without macerating or damaging the surrounding healthy skin.
B
200~67o More specifically, the wound dressing of the present invention is suitable for cleaning and disinfecting a wound in a single application, and comprises a composition of anhydrous magnesium sulfate in a water-miscible base. The composition is subsequently impregnated in an absorbing material. The resulting dressing is then sealed-packed into a suitable dressing container, and sterilized.
DESCRIPTION OF THE lNv~NLIoN:
The present invention relates to a wound dressing having anhydrous magnesium sulfate as the active ingredient. The dressing of the present invention is capable of absorbing and adsorbing exudate, transudate, pus, bacteria and undesirable necrotic tissue. At the same time, the dressing disinfects the wound and its surrounding area without macerating or damaging the surrounding healthy skin.
All this eases the granulation of the wound, and therefore accelerates the healing process.
The dressing of the present invention consists of a composition in the form of a paste formed by the addition of anhydrous magnesium sulfate to a water-miscible base, such as glycerine or propylene glycol. The concentrations are ranging from 35 to 55 ~ by weight of anhydrous magnesium sulfate, B
and from 45 to 65 ~ by weight of water-miscible base.
The preferred concentrations are 45 % by weight of anhydrous magnesium sulfate, and 55~ by weight of water-miscible base. Glycerine is the preferred water-miscible base. The paste is then put between twopieces of absorbing material, preferably 100 ~ cotton, and sterilized. It is then placed into a suitable dressing container, hermetically sealed, and sterilized.
The advantages of this wound dressing are important. It can be used by anyone seconds after wounding, being therefore time saving. Compared to antibiotics, steroids or enzymes, it is by far the least expensive treatment. Also, the constituents of the composition are readily available commercial compounds. The process for the preparation of the dressing does not involve any complicated procedure.
The dressing of the present invention can be used on burns, infected ulcers, open wounds, cuts, abrasions, furuncle, whitlow and the like. The application of the dressing creates a hypertonic and antiseptic environment, wherein absorption and adsorption of bacteria and necrotic tissue is induced by osmosis and bacteriocidal effect. The wound and the area surrounding it are therefore thoroughly cleaned, dried and disinfected by the application of the dressing. This favors granulation, and consequently accelerates the healing process without B
maceration of healthy skin around the wound or the ulcer.
Another advantage of this invention is that it renders the use of antiseptic, enzymes and/or antibiotics unnecessary, since the present dressing has already asepticized the area, when put on the affected area moments after wounding.
Therefore, the application of the dressing has two crucial effects: first, it allows one to treat a wound within a short period of time, thus reducing the risks of infection. Second, it favors granulation and healing of the wound.
It is to be understood that the dressing of the present invention can be provided in various sizes and shapes appropriate to the sizes of wounds.
Preferably, the dressing will be provided in square shapes of 5 to 36 cm2 and will be packaged in hermetically sealed and sterilized, tear-open, foil pouches.
Especially because of its size and its low cost price per unit, compared to antibiotics or steroids, the wound dressing of the present invention is ideal in First Aid kit for camping, fishing, hunting, or any other outdoor activity. Hospitals and homes are other places where the dressing of the present invention is very useful. Considering its B
200~67G
size, the dressing is particularly desirable in hospitals, where the storage space is relatively limited.
To enhance healing, it is recommended to repeat the application of the dressing on the wound once or twice a day. However, a single cautious application on small wounds is generally sufficient.
The following example illustrates preferred embodiments of the invention. It should not be construed as limiting the claims hereto.
Example 1:
The dressing of the present invention is prepared the following way:
45 g of anhydrous magnesium sulfate is heated at 100C for 1 hour. Then, 55 g of glycerine is added, and the compounds are mixed until a paste is obtained. 10 g of the resulting paste is placed between two 100 ~ cotton square surgical sponges of about 5cm2. The dressing thus obtained is sealed-packed into a suitable dressing container, and sterilized by X-rays exposure.
~'
It is common practice to apply a fluid antiseptic on wounds, cuts, lacerations, burns and skin infections. In recent years, wound dressings for use on superficial burns, cuts and abrasions have been developed, providing a clear plastic film over the affected area.
These plastic wound dressings or "plastic bandages" are usually solutions of an acrylic or methacrylic co-polymer dissolved in a volatile non-aqueous organic solvent of low boiling point, such as ethyl acetate, acetone, ethyl alcohol or methylene chloride or mixtures thereof.
These bandages, however, have no antibacterial activity, and should therefore only be applied after thorough disinfection of the skin. A
most serious drawback of these liquid bandages is that the non-aqueous solvent containing the active ingredient(s) can cause considerable pain, if applied to open wounds, cuts and abrasions. Also, for good adherence, such liquid bandages can only be applied to perfectly dry skin. This makes them less suitable where the skin is contaminated by body fluids such as blood, perspiration or pus which is a situation frequently encountered with open wounds.
2no~670 Open wounds, cuts and abrasions can become threatening if they are not taken care of within a short period of time. Lack to do so can lead to dangerous infections which may require much more expensive treatment, such as the administration of antibiotics, steroids or enzymes, in order to control and eliminate the infection. Instant treatment and disinfection of open wound is therefore critical.
It would be highly desirable to have a wound dressing capable of cleaning up a wound by absorbing all exudate and transudate, removing undesirable necrotic tissue, pus and bacteria, and disinfecting the wound and the surrounding area. It would also be desirable that such dressing can promote granulation and healing of the wound in a single application.
SUMMARY OF THE lNv~:N-LlON:
In accordance with the present invention, there is now provided a sterile wound dressing suitable for cleaning and disinfecting a wound and its surrounding area, promoting granulation and favoring therefore the healing of the wound, without macerating or damaging the surrounding healthy skin.
B
200~67o More specifically, the wound dressing of the present invention is suitable for cleaning and disinfecting a wound in a single application, and comprises a composition of anhydrous magnesium sulfate in a water-miscible base. The composition is subsequently impregnated in an absorbing material. The resulting dressing is then sealed-packed into a suitable dressing container, and sterilized.
DESCRIPTION OF THE lNv~NLIoN:
The present invention relates to a wound dressing having anhydrous magnesium sulfate as the active ingredient. The dressing of the present invention is capable of absorbing and adsorbing exudate, transudate, pus, bacteria and undesirable necrotic tissue. At the same time, the dressing disinfects the wound and its surrounding area without macerating or damaging the surrounding healthy skin.
All this eases the granulation of the wound, and therefore accelerates the healing process.
The dressing of the present invention consists of a composition in the form of a paste formed by the addition of anhydrous magnesium sulfate to a water-miscible base, such as glycerine or propylene glycol. The concentrations are ranging from 35 to 55 ~ by weight of anhydrous magnesium sulfate, B
and from 45 to 65 ~ by weight of water-miscible base.
The preferred concentrations are 45 % by weight of anhydrous magnesium sulfate, and 55~ by weight of water-miscible base. Glycerine is the preferred water-miscible base. The paste is then put between twopieces of absorbing material, preferably 100 ~ cotton, and sterilized. It is then placed into a suitable dressing container, hermetically sealed, and sterilized.
The advantages of this wound dressing are important. It can be used by anyone seconds after wounding, being therefore time saving. Compared to antibiotics, steroids or enzymes, it is by far the least expensive treatment. Also, the constituents of the composition are readily available commercial compounds. The process for the preparation of the dressing does not involve any complicated procedure.
The dressing of the present invention can be used on burns, infected ulcers, open wounds, cuts, abrasions, furuncle, whitlow and the like. The application of the dressing creates a hypertonic and antiseptic environment, wherein absorption and adsorption of bacteria and necrotic tissue is induced by osmosis and bacteriocidal effect. The wound and the area surrounding it are therefore thoroughly cleaned, dried and disinfected by the application of the dressing. This favors granulation, and consequently accelerates the healing process without B
maceration of healthy skin around the wound or the ulcer.
Another advantage of this invention is that it renders the use of antiseptic, enzymes and/or antibiotics unnecessary, since the present dressing has already asepticized the area, when put on the affected area moments after wounding.
Therefore, the application of the dressing has two crucial effects: first, it allows one to treat a wound within a short period of time, thus reducing the risks of infection. Second, it favors granulation and healing of the wound.
It is to be understood that the dressing of the present invention can be provided in various sizes and shapes appropriate to the sizes of wounds.
Preferably, the dressing will be provided in square shapes of 5 to 36 cm2 and will be packaged in hermetically sealed and sterilized, tear-open, foil pouches.
Especially because of its size and its low cost price per unit, compared to antibiotics or steroids, the wound dressing of the present invention is ideal in First Aid kit for camping, fishing, hunting, or any other outdoor activity. Hospitals and homes are other places where the dressing of the present invention is very useful. Considering its B
200~67G
size, the dressing is particularly desirable in hospitals, where the storage space is relatively limited.
To enhance healing, it is recommended to repeat the application of the dressing on the wound once or twice a day. However, a single cautious application on small wounds is generally sufficient.
The following example illustrates preferred embodiments of the invention. It should not be construed as limiting the claims hereto.
Example 1:
The dressing of the present invention is prepared the following way:
45 g of anhydrous magnesium sulfate is heated at 100C for 1 hour. Then, 55 g of glycerine is added, and the compounds are mixed until a paste is obtained. 10 g of the resulting paste is placed between two 100 ~ cotton square surgical sponges of about 5cm2. The dressing thus obtained is sealed-packed into a suitable dressing container, and sterilized by X-rays exposure.
~'
Claims (9)
1. A sterile wound dressing suitable for use in cleaning and disinfecting a wound in a single application of said dressing of said wound, said sterile wounddressing being suitable for absorption and adsorption of exudate, transudate, bacteria, pus and necrotic tissue resulting from an infected wound or ulcer, andbeing suitable for disinfection of said wound or ulcer, said wound dressing comprising a composition of anhydrous magnesium sulfate in a water-miscible base, impregnated in an absorbing material.
2. A wound dressing according to Claim 1, wherein the water-miscible base is glycerine and the absorbing material is cotton.
3. A wound dressing according to Claim 2, wherein the concentration of magnesium sulfate is ranging from 35 to 55 % by weight, and the concentration ofglycerine is ranging from 45 to 65 % by weight.
4. A wound dressing according to Claim 2, wherein the concentration of magnesium sulfate is 45% by weight, and the concentration of glycerine is 55%.
5. The use of a sterile wound dressing according to claim 1 as a medicament for wound cleaning and desinfection.
6. The use of a wound dressing according to Claim 5, wherein the water-miscible base is glycerine and the absorbing material is cotton.
7. The use of a wound dressing according to Claim 5, wherein the concentration of magnesium sulfate is ranging from 35 to 55 % by weight, and theconcentration of glycerine is ranging from 45 to 65 % by weight.
8. The use of a wound dressing according to Claim 5, wherein the concentration of magnesium sulfate is 45% by weight, and the concentration of glycerine is 55%.
9. A sterile dressing container device comprising:
- a hermetically sealed body comprising a pair of opposing sheets of a hermetic material, each sheet comprising at least one layer, said sheets being hermetically joined on each side and adapted to house a wound dressing;
- a sterile wound dressing received within said hermetically sealed body, said wound dressing being adapted for use in cleaning and disinfecting a wound in a single application of said dressing of said wound, said sterile wound dressing being suitable for absorption and adsorption of exudate, transudate, bacteria, pus andnecrotic tissue resulting from an infected wound or ulcer, and also suitable fordisinfection of said wound or ulcer, said wound dressing including a composition of anhydrous magnesium sulfate in a water-miscible base, impregnated in an absorbing material.
- a hermetically sealed body comprising a pair of opposing sheets of a hermetic material, each sheet comprising at least one layer, said sheets being hermetically joined on each side and adapted to house a wound dressing;
- a sterile wound dressing received within said hermetically sealed body, said wound dressing being adapted for use in cleaning and disinfecting a wound in a single application of said dressing of said wound, said sterile wound dressing being suitable for absorption and adsorption of exudate, transudate, bacteria, pus andnecrotic tissue resulting from an infected wound or ulcer, and also suitable fordisinfection of said wound or ulcer, said wound dressing including a composition of anhydrous magnesium sulfate in a water-miscible base, impregnated in an absorbing material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2009670 CA2009670C (en) | 1990-02-09 | 1990-02-09 | Wound dressing |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA 2009670 CA2009670C (en) | 1990-02-09 | 1990-02-09 | Wound dressing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2009670A1 CA2009670A1 (en) | 1991-08-09 |
| CA2009670C true CA2009670C (en) | 1997-07-01 |
Family
ID=4144242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2009670 Expired - Lifetime CA2009670C (en) | 1990-02-09 | 1990-02-09 | Wound dressing |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2009670C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19527820A1 (en) * | 1995-07-28 | 1997-01-30 | Leniger Follert Elfriede Prof | Medicines for the treatment of ulcers, especially in the case of arterial and venous circulatory disorders in the extremities, in chronic venous insufficiency and lymphedema |
-
1990
- 1990-02-09 CA CA 2009670 patent/CA2009670C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2009670A1 (en) | 1991-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |