CA1339190C - Compositions et methodes de fabrication de medicaments dans des poudres comprimees - Google Patents

Compositions et methodes de fabrication de medicaments dans des poudres comprimees

Info

Publication number
CA1339190C
CA1339190C CA000609378A CA609378A CA1339190C CA 1339190 C CA1339190 C CA 1339190C CA 000609378 A CA000609378 A CA 000609378A CA 609378 A CA609378 A CA 609378A CA 1339190 C CA1339190 C CA 1339190C
Authority
CA
Canada
Prior art keywords
drug
patient
producing
transmucosal delivery
lollipop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000609378A
Other languages
English (en)
Inventor
Theodore H. Stanley
Brian Hague
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah
Original Assignee
University of Utah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US06/729,301 priority Critical patent/US4671953A/en
Priority to EP86303128A priority patent/EP0200490B1/fr
Priority to DE3650189T priority patent/DE3650189T2/de
Priority to AT90114597T priority patent/ATE116131T1/de
Priority to EP90114597A priority patent/EP0404205B1/fr
Priority to CA000507763A priority patent/CA1271421A/fr
Priority to US07/060,046 priority patent/US4885173A/en
Priority to US07/060,045 priority patent/US4863737A/en
Priority to PCT/US1989/003518 priority patent/WO1991003099A1/fr
Priority to EP89909497A priority patent/EP0487520B1/fr
Application filed by University of Utah filed Critical University of Utah
Priority to CA000609378A priority patent/CA1339190C/fr
Priority to CA0609378A priority patent/CA1338978C/fr
Priority to AU42063/89A priority patent/AU641622B2/en
Priority to PCT/US1989/003802 priority patent/WO1991003234A1/fr
Priority to US07/403,743 priority patent/US5122127A/en
Priority to EP89910318A priority patent/EP0490891B1/fr
Priority to US07/402,881 priority patent/US5132114A/en
Priority to US07/403,751 priority patent/US5288497A/en
Priority to DE68926169T priority patent/DE68926169T2/de
Priority to US07/403,752 priority patent/US5288498A/en
Priority to JP1509843A priority patent/JP2704019B2/ja
Priority to DK199200193A priority patent/DK175779B1/da
Priority to DK030192A priority patent/DK30192A/da
Priority to US08/376,642 priority patent/US5484602A/en
Application granted granted Critical
Publication of CA1339190C publication Critical patent/CA1339190C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A23G3/54—Composite products, e.g. layered, coated, filled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
CA000609378A 1985-05-01 1989-08-24 Compositions et methodes de fabrication de medicaments dans des poudres comprimees Expired - Lifetime CA1339190C (fr)

Priority Applications (24)

Application Number Priority Date Filing Date Title
US06/729,301 US4671953A (en) 1985-05-01 1985-05-01 Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
DE3650189T DE3650189T2 (de) 1985-05-01 1986-04-25 Mittel zur nichsystemischen Verabreichung von Sedativa und Analgetika.
AT90114597T ATE116131T1 (de) 1985-05-01 1986-04-25 Mittel zur nichsystemischen verabreichung von sedativa und analgetika.
EP90114597A EP0404205B1 (fr) 1985-05-01 1986-04-25 Compositions pour l'administration non systémique d'agents sédatifs et analgésiques
EP86303128A EP0200490B1 (fr) 1985-05-01 1986-04-25 Compositions pour l'administration non-systémique d'agents sédatifs, analgéniques et anesthésiques
CA000507763A CA1271421A (fr) 1985-05-01 1986-04-28 Methodes et produits pour l'administration non traumatisante de sedatifs, d'analgesiques et d'anesthesiques
US07/060,046 US4885173A (en) 1985-05-01 1987-06-08 Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities
US07/060,045 US4863737A (en) 1985-05-01 1987-06-08 Compositions and methods of manufacture of compressed powder medicaments
PCT/US1989/003518 WO1991003099A1 (fr) 1985-05-01 1989-08-16 Medicaments a base de poudre comprimee
EP89909497A EP0487520B1 (fr) 1985-05-01 1989-08-16 Medicaments a base de poudre comprimee
CA0609378A CA1338978C (fr) 1985-05-01 1989-08-24 Compositions et méthodes de fabrication de médicaments dans des poudres comprimées
CA000609378A CA1339190C (fr) 1989-08-24 1989-08-24 Compositions et methodes de fabrication de medicaments dans des poudres comprimees
AU42063/89A AU641622B2 (en) 1985-05-01 1989-09-05 Drug containing matrix
US07/403,743 US5122127A (en) 1985-05-01 1989-09-05 Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
EP89910318A EP0490891B1 (fr) 1985-05-01 1989-09-05 Matrice contenant un medicament
US07/402,881 US5132114A (en) 1985-05-01 1989-09-05 Compositions and methods of manufacture of compressed powder medicaments
US07/403,751 US5288497A (en) 1985-05-01 1989-09-05 Compositions of oral dissolvable medicaments
DE68926169T DE68926169T2 (de) 1985-05-01 1989-09-05 Heilmittel enthaltende matrize
PCT/US1989/003802 WO1991003234A1 (fr) 1985-05-01 1989-09-05 Matrice contenant un medicament
JP1509843A JP2704019B2 (ja) 1985-05-01 1989-09-05 薬剤含有マトリックス
US07/403,752 US5288498A (en) 1985-05-01 1989-09-05 Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
DK199200193A DK175779B1 (da) 1985-05-01 1992-02-14 Komprimerede pulverlægemidler
DK030192A DK30192A (da) 1985-05-01 1992-03-05 Laegemiddelholdig matrix
US08/376,642 US5484602A (en) 1985-05-01 1995-01-20 Methods and compositions for noninvasive dose-to-effect administration of drugs with cardiovascular or renal vascular activities

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000609378A CA1339190C (fr) 1989-08-24 1989-08-24 Compositions et methodes de fabrication de medicaments dans des poudres comprimees

Publications (1)

Publication Number Publication Date
CA1339190C true CA1339190C (fr) 1997-07-29

Family

ID=4140500

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000609378A Expired - Lifetime CA1339190C (fr) 1985-05-01 1989-08-24 Compositions et methodes de fabrication de medicaments dans des poudres comprimees

Country Status (1)

Country Link
CA (1) CA1339190C (fr)

Similar Documents

Publication Publication Date Title
US4863737A (en) Compositions and methods of manufacture of compressed powder medicaments
US5132114A (en) Compositions and methods of manufacture of compressed powder medicaments
EP0487520B1 (fr) Medicaments a base de poudre comprimee
AU645265B2 (en) Compositions and methods of manufacture of oral dissolvable medicaments
US5785989A (en) Compositions and methods of manufacturing of oral dissolvable medicaments
EP0490944B1 (fr) Forme de dosage transmucosique
US5855908A (en) Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient
US20020160043A1 (en) Compositions and method of manufacture for oral dissolvable dosage forms
US6197334B1 (en) Lozenge and method of making
EP0493380B1 (fr) Methode de preparation permettant l'administration non invasive de medicaments lipophiles doses en fonction de l'effet recherche
AU641127B2 (en) Compressed powder medicaments
CA1339190C (fr) Compositions et methodes de fabrication de medicaments dans des poudres comprimees
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CA1339075C (fr) Methodes et compositions pour l'administration dose-effet non invasive de medicaments lipophiles

Legal Events

Date Code Title Description
MKEX Expiry

Effective date: 20140729