CA1329808C - Utilisation d'analogues de phencyclidine modifiee a anneau piperidine comme agents anticonvulsivants - Google Patents

Utilisation d'analogues de phencyclidine modifiee a anneau piperidine comme agents anticonvulsivants

Info

Publication number
CA1329808C
CA1329808C CA000594589A CA594589A CA1329808C CA 1329808 C CA1329808 C CA 1329808C CA 000594589 A CA000594589 A CA 000594589A CA 594589 A CA594589 A CA 594589A CA 1329808 C CA1329808 C CA 1329808C
Authority
CA
Canada
Prior art keywords
compounds
compound
alkyl
seizures
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000594589A
Other languages
English (en)
Inventor
Andrew Thurkauf
Michael A. Rogawski
Kenner Rice
Arthur E. Jacobson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DEPARTMENT OF COMMERCE
Original Assignee
DEPARTMENT OF COMMERCE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DEPARTMENT OF COMMERCE filed Critical DEPARTMENT OF COMMERCE
Application granted granted Critical
Publication of CA1329808C publication Critical patent/CA1329808C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000594589A 1988-03-25 1989-03-23 Utilisation d'analogues de phencyclidine modifiee a anneau piperidine comme agents anticonvulsivants Expired - Fee Related CA1329808C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17292288A 1988-03-25 1988-03-25
US07/172,922 1988-03-25

Publications (1)

Publication Number Publication Date
CA1329808C true CA1329808C (fr) 1994-05-24

Family

ID=22629762

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000594589A Expired - Fee Related CA1329808C (fr) 1988-03-25 1989-03-23 Utilisation d'analogues de phencyclidine modifiee a anneau piperidine comme agents anticonvulsivants

Country Status (3)

Country Link
AU (1) AU3366389A (fr)
CA (1) CA1329808C (fr)
WO (1) WO1989009209A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB853775A (en) * 1957-09-19 1960-11-09 Parke Davis & Co Pharmaceutical compositions and methods for producing phenylcyclohexane compounds
BE565262A (fr) * 1957-09-19
US3097207A (en) * 1958-03-06 1963-07-09 Parke Davis & Co 1-halophenyl and 1-alkoxyphenyl cyclohexylamines
GB948071A (en) * 1959-05-01 1964-01-29 May & Baker Ltd New heterocyclic compounds
US3192219A (en) * 1960-04-04 1965-06-29 Parke Davis & Co Process for producing certain new 1-phenylcyclohexylamine compounds
US3097136A (en) * 1960-04-04 1963-07-09 Parke Davis & Co Process for producing a depressant-like effect on the central nervous system
US3145229A (en) * 1960-04-04 1964-08-18 Parke Davis & Co Process for the production of nu-substituted-1-phenylcyclohexylamines
GB1207731A (en) * 1968-05-14 1970-10-07 Reckitt & Sons Ltd Derivatives of pyrrolidine
US3652769A (en) * 1969-10-01 1972-03-28 Merck & Co Inc Cycloalkylamines in the treatment of mental disorders involving depression and compositions therefor
US4460604A (en) * 1976-06-03 1984-07-17 The Upjohn Company 4-Amino-4-aryl-cyclohexanones
US4113866A (en) * 1977-04-01 1978-09-12 The Upjohn Company Analgetic compounds, compositions and process of treatment
ZA821577B (en) * 1981-04-06 1983-03-30 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
AU3366389A (en) 1989-10-16
WO1989009209A1 (fr) 1989-10-05

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