CA1315196C - Method of disinfecting hard surfaces - Google Patents
Method of disinfecting hard surfacesInfo
- Publication number
- CA1315196C CA1315196C CA000530369A CA530369A CA1315196C CA 1315196 C CA1315196 C CA 1315196C CA 000530369 A CA000530369 A CA 000530369A CA 530369 A CA530369 A CA 530369A CA 1315196 C CA1315196 C CA 1315196C
- Authority
- CA
- Canada
- Prior art keywords
- acid
- composition
- isopropanol
- ppm
- hard surfaces
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/02—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/26—Phosphorus; Compounds thereof
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
ABSTRACT
A METHOD OF DISINFECTING HARD SURFACES
Hard surfaces are disinfected using alcoholic microbiocidal compositions which contain reduced alcohol and anti-microbial concentrations. The compositions comprise an aqueous solution of a lower alcohol, an acid and an anti-microbially effective amount of an amino- or ammonium- based microbiocide, the pH of the total composition not exceeding 5. The reduced alcohol and microbiocide levels improve safety of handling and suitability for use on surfaces which contact food. The compositions demonstrate both disinfectant and preservative properties.
A METHOD OF DISINFECTING HARD SURFACES
Hard surfaces are disinfected using alcoholic microbiocidal compositions which contain reduced alcohol and anti-microbial concentrations. The compositions comprise an aqueous solution of a lower alcohol, an acid and an anti-microbially effective amount of an amino- or ammonium- based microbiocide, the pH of the total composition not exceeding 5. The reduced alcohol and microbiocide levels improve safety of handling and suitability for use on surfaces which contact food. The compositions demonstrate both disinfectant and preservative properties.
Description
131519~
A METHOD OF DISINFECTING HARD SURFACES
The present invention relates to a method of disinfecting hard surfaces using disinfectant compositions, in particular, compositions comprising an aqueous solution of a lower alcohol and an anti-microbial compound. The method is suitable for, although not restricted to food-processing disinfection and kitchen hygiene.
Hard-surface contamination by bacteria, yeasts and moulds represents a hazard in food processing and kitchen hygiene; and may result in food-poisoning micro-organisms being transferred to food product~.
Accordingly, there is a need for disinfectant product~
which reduce the numbers of micro-organisms on food-contact surfaces to acceptable levels and help to prevent those surfaces from being re-contaminated.
Effective biocidal compositions are known in the art.
In general, in order to achieve the necessary level of disinfecting action, they contain either high levels of alcohol, which is undesirable in view of the evident safety hazards during processing, storage and application, or they contain relatively high levels of one or more biocidal compounds, which i8 also undesirable for application to surfaces coming into contact with food products.
. ' 131~96 It has now been found that in compositions based on aqueous solutions o~ alcohol and conventional amino- or an~onium-based anti-microbial compounds, the inclusion of (preferably organic) acids in amounts sufficient to yield acid pH-values, allow a considerable reduction in the levels of both the alcohol component and the biocidal compound. This is particularly surprising since the biocidal compounds of this type are generally thought to be more effective at neutral or alkaline pH values.
Accordingly, the present invention provides a method of disinfecting hard surfaces by application thereto of an aqueous disinfectant composition comprising:
a) at least 10% by volume of a lower alcohol selected from the group consisting of ethanol, isopropanol and mixtures thereof;
b) 5 to 500 ppm of an anti-microbial agent which is a di(C8-C18) alkyl di(C1-C4)alkyl ammonium chloride, and c) 0.1 to 10~ by weight of an acidic compound; said composition having a pH of 2-4.
Thus, we have found that the method according to the present invention, not only avoids the aforementioned disadvantages, but also provides both disinfecting action at application and preservative action after application, i.e. protecting the treated surface from re-contamination.
'" . ~, 131~196 An example of a suitable anti-microbial agent is didecyl dimethyl a~monium chloride such as Bardac 22 (a registered trademark by Lonza, Switzerland).
In general, the anti-microbial compounds are included in amounts of from S to 500 ppm, in particular 5 to 100 ppm. Preferred levels of the anti-microbial compound range from 20 to 50 ppm.
The second essential component of the composition is a lower alcohol, namely ethanol or isopropanol, the latter of which, optionally in admixture with the first, is preferred. Where both are present, the volume ratio of ethanol to isopropanol ~s preferably from 1:1 to 1:3.
The concentration of the alcohol component is at least 10~ v/v and normally lies within the range of from 10 to 50% v/v. Preferred are concentrations in the range of from 15 to 40% v/v, in particular 20 to 40% v/v.
~0 The third essential component of the composition is an acidic compound. Although both mineral and organic acids capable of providing this pH may suitably be included, when intended for the particular field of application referred to above, it is preferred to use food-grade alkyl carboxylic acids or hydroxyacids. Suitable such acids include acetic, ~ ` ~J
131~196 citric, fumaric, lactic, malic and tartaric acid, the preferred members of which are citric and lactic acid.
The acidic compound is included in an amount of from 0.1 to 10~ by weight, and preferably in an amount of from 2 to 5% by weight. The amount should be sufficient to provide the composition with a pH-value of from 2 to 4.
The composition may include water and, optionally, minor ingredients to improve its effectiveness and/or consumer acceptability. More in particular, the composition may contain minor amounts of surfactants, wetting agents, colouring agents and perfumes.
The method will normally involve application of the composition by spraying or sprinkling thereof onto the surface to be treated, in view whereof the composition may be fixed with a propellant to provide a formulation suitable for use as an aerosol spray.
Alternatively, the compositions may be applied to the surface being impregnated in a substrate of woven or _ .~ ,i ~315196 non-woven (e.g. paper) material to form a disinfectant wet wipe.
The invention will now be further illustrated by way of example.
Example 1 Compositions were tested having the following basic formulation:
10 isopropanol 30% v/v acid 0.1 or 1% by weight didecyl dimethyl ammonium chloride 25 or 50 ppm water balance The compositions were adjusted to pH = by HC1 or NaOH.
The anti-microbial activity was measured against two yeasts, Saccharomyces cerevisiae and Zygosaccharmoyces rouxii, using the 20 quaternary ammonium compound at a level of 50 ppm, and against one type of bacterium, Escherichia coli, using the quaternary ammonium compound at a level of 25 ppm. The anti-microbial activity was measured by way of a standard suspension test at 25C and using a contact time of 5 minutes.
The data in Table 1 demonstrate the significant enhancement of the activity of the quaternary ammonium compound by organic acids, in particular at the 1~ by weight levels.
1~15196 - 6 - C.7078 Logl0 reduction in viable counts in the presence of 50 ppm (yeasts) or 25 ppm (E. coli) didecyl dimethyl ammonium chloride S. Z. E.
Acid % cerevisiae rouxii coli None added 2.18 0.002.10 Orthophosphoric 0.1 2.170.00 2.11 0.1 3.87 0.404.70 Sulphamic 0.1 2.72 0.082.20 1.0 3.45 0.094.05 Glycolic 0.1 3.42 0.462.47 1.0 >4.60 3.46>5.10 Acetic 0.1 - - 2.44 1.0 - - >5.73 Acetic:Formic(1:1) 0.1 - - 3.74 1.0 >4.60 >4.60>5.10 Example 2 A composition was formulated comprising 30% v/v isopropanol, 1% by weight acetic acid, 25 ppm of didecyl dimethyl ammonium chloride and water. This composition was compared with the same composition without the ammonium compound to test its anti-microbial activity when sprayed onto Staphylococcus aureus bacteria dried on PCV
tiles. The Staphylococcus aureus bacterium has been found to be one of the most resistant vegetative when dried onto 13~ ~19~
_ 7 - C.7078 hard surfaces and it also constitutes a food-poisoning risk. From Table 2 it is evident that the composition containing both the acid and the ammonium compound is highly effective.
Spray composition Logl0 Bacteria recovered 2 hours after spraving lO Water 4.2 30% isopropanol + l~ acetic acid4.1 30% isopropanol + 1% acetic acid and 25 ppm QAC <2.3 Example 3 Compositions containing 30%v/v of isopropanol, 25 ppm of didecyl dimethyl ammonium chloride, the amounts and types of acids indicated in Table 3 and water were tested in the same manner as in Example 2. The results in Table 3 clearly indicate that also other types of food-grade organic acids can suitably be used to achieve satisfactory anti-microbial action.
131al96 - 8 - C.7078 Spray liquid Log10 reduction in viable bacteria after: 5 min 2 h Water 0.1 1.5 Isopropanol 0.8 2.6 lO Isopropanol + 2% lactic acid 3.7 4.9 Isopropanol + 5% lactic acid 4.7 >5 Isopropanol + 2~ citric acid 4.2 >5 Isopropanol + 5% citric acid >S >5 Isopropanol + 2% acetic acid >5 >5 15 Isopropanol + 5% acetic acid >5 >5
A METHOD OF DISINFECTING HARD SURFACES
The present invention relates to a method of disinfecting hard surfaces using disinfectant compositions, in particular, compositions comprising an aqueous solution of a lower alcohol and an anti-microbial compound. The method is suitable for, although not restricted to food-processing disinfection and kitchen hygiene.
Hard-surface contamination by bacteria, yeasts and moulds represents a hazard in food processing and kitchen hygiene; and may result in food-poisoning micro-organisms being transferred to food product~.
Accordingly, there is a need for disinfectant product~
which reduce the numbers of micro-organisms on food-contact surfaces to acceptable levels and help to prevent those surfaces from being re-contaminated.
Effective biocidal compositions are known in the art.
In general, in order to achieve the necessary level of disinfecting action, they contain either high levels of alcohol, which is undesirable in view of the evident safety hazards during processing, storage and application, or they contain relatively high levels of one or more biocidal compounds, which i8 also undesirable for application to surfaces coming into contact with food products.
. ' 131~96 It has now been found that in compositions based on aqueous solutions o~ alcohol and conventional amino- or an~onium-based anti-microbial compounds, the inclusion of (preferably organic) acids in amounts sufficient to yield acid pH-values, allow a considerable reduction in the levels of both the alcohol component and the biocidal compound. This is particularly surprising since the biocidal compounds of this type are generally thought to be more effective at neutral or alkaline pH values.
Accordingly, the present invention provides a method of disinfecting hard surfaces by application thereto of an aqueous disinfectant composition comprising:
a) at least 10% by volume of a lower alcohol selected from the group consisting of ethanol, isopropanol and mixtures thereof;
b) 5 to 500 ppm of an anti-microbial agent which is a di(C8-C18) alkyl di(C1-C4)alkyl ammonium chloride, and c) 0.1 to 10~ by weight of an acidic compound; said composition having a pH of 2-4.
Thus, we have found that the method according to the present invention, not only avoids the aforementioned disadvantages, but also provides both disinfecting action at application and preservative action after application, i.e. protecting the treated surface from re-contamination.
'" . ~, 131~196 An example of a suitable anti-microbial agent is didecyl dimethyl a~monium chloride such as Bardac 22 (a registered trademark by Lonza, Switzerland).
In general, the anti-microbial compounds are included in amounts of from S to 500 ppm, in particular 5 to 100 ppm. Preferred levels of the anti-microbial compound range from 20 to 50 ppm.
The second essential component of the composition is a lower alcohol, namely ethanol or isopropanol, the latter of which, optionally in admixture with the first, is preferred. Where both are present, the volume ratio of ethanol to isopropanol ~s preferably from 1:1 to 1:3.
The concentration of the alcohol component is at least 10~ v/v and normally lies within the range of from 10 to 50% v/v. Preferred are concentrations in the range of from 15 to 40% v/v, in particular 20 to 40% v/v.
~0 The third essential component of the composition is an acidic compound. Although both mineral and organic acids capable of providing this pH may suitably be included, when intended for the particular field of application referred to above, it is preferred to use food-grade alkyl carboxylic acids or hydroxyacids. Suitable such acids include acetic, ~ ` ~J
131~196 citric, fumaric, lactic, malic and tartaric acid, the preferred members of which are citric and lactic acid.
The acidic compound is included in an amount of from 0.1 to 10~ by weight, and preferably in an amount of from 2 to 5% by weight. The amount should be sufficient to provide the composition with a pH-value of from 2 to 4.
The composition may include water and, optionally, minor ingredients to improve its effectiveness and/or consumer acceptability. More in particular, the composition may contain minor amounts of surfactants, wetting agents, colouring agents and perfumes.
The method will normally involve application of the composition by spraying or sprinkling thereof onto the surface to be treated, in view whereof the composition may be fixed with a propellant to provide a formulation suitable for use as an aerosol spray.
Alternatively, the compositions may be applied to the surface being impregnated in a substrate of woven or _ .~ ,i ~315196 non-woven (e.g. paper) material to form a disinfectant wet wipe.
The invention will now be further illustrated by way of example.
Example 1 Compositions were tested having the following basic formulation:
10 isopropanol 30% v/v acid 0.1 or 1% by weight didecyl dimethyl ammonium chloride 25 or 50 ppm water balance The compositions were adjusted to pH = by HC1 or NaOH.
The anti-microbial activity was measured against two yeasts, Saccharomyces cerevisiae and Zygosaccharmoyces rouxii, using the 20 quaternary ammonium compound at a level of 50 ppm, and against one type of bacterium, Escherichia coli, using the quaternary ammonium compound at a level of 25 ppm. The anti-microbial activity was measured by way of a standard suspension test at 25C and using a contact time of 5 minutes.
The data in Table 1 demonstrate the significant enhancement of the activity of the quaternary ammonium compound by organic acids, in particular at the 1~ by weight levels.
1~15196 - 6 - C.7078 Logl0 reduction in viable counts in the presence of 50 ppm (yeasts) or 25 ppm (E. coli) didecyl dimethyl ammonium chloride S. Z. E.
Acid % cerevisiae rouxii coli None added 2.18 0.002.10 Orthophosphoric 0.1 2.170.00 2.11 0.1 3.87 0.404.70 Sulphamic 0.1 2.72 0.082.20 1.0 3.45 0.094.05 Glycolic 0.1 3.42 0.462.47 1.0 >4.60 3.46>5.10 Acetic 0.1 - - 2.44 1.0 - - >5.73 Acetic:Formic(1:1) 0.1 - - 3.74 1.0 >4.60 >4.60>5.10 Example 2 A composition was formulated comprising 30% v/v isopropanol, 1% by weight acetic acid, 25 ppm of didecyl dimethyl ammonium chloride and water. This composition was compared with the same composition without the ammonium compound to test its anti-microbial activity when sprayed onto Staphylococcus aureus bacteria dried on PCV
tiles. The Staphylococcus aureus bacterium has been found to be one of the most resistant vegetative when dried onto 13~ ~19~
_ 7 - C.7078 hard surfaces and it also constitutes a food-poisoning risk. From Table 2 it is evident that the composition containing both the acid and the ammonium compound is highly effective.
Spray composition Logl0 Bacteria recovered 2 hours after spraving lO Water 4.2 30% isopropanol + l~ acetic acid4.1 30% isopropanol + 1% acetic acid and 25 ppm QAC <2.3 Example 3 Compositions containing 30%v/v of isopropanol, 25 ppm of didecyl dimethyl ammonium chloride, the amounts and types of acids indicated in Table 3 and water were tested in the same manner as in Example 2. The results in Table 3 clearly indicate that also other types of food-grade organic acids can suitably be used to achieve satisfactory anti-microbial action.
131al96 - 8 - C.7078 Spray liquid Log10 reduction in viable bacteria after: 5 min 2 h Water 0.1 1.5 Isopropanol 0.8 2.6 lO Isopropanol + 2% lactic acid 3.7 4.9 Isopropanol + 5% lactic acid 4.7 >5 Isopropanol + 2~ citric acid 4.2 >5 Isopropanol + 5% citric acid >S >5 Isopropanol + 2% acetic acid >5 >5 15 Isopropanol + 5% acetic acid >5 >5
Claims (8)
1. A method of disinfecting hard surfaces by application thereto of an aqueous disinfectant composition comprising:
(a) at least 10 % by volume of a lower alcohol selected from the group consisting of ethanol, isopropanol and mixtures thereof;
(b) 5 to 500 ppm of an anti-microbial agent which is a di(C8-C18) alkyl di(C1-C4)alkyl ammonium chloride, and (c) 0.1 to 10% by weight of an acidic compound; said composition having a pH of 2-4.
(a) at least 10 % by volume of a lower alcohol selected from the group consisting of ethanol, isopropanol and mixtures thereof;
(b) 5 to 500 ppm of an anti-microbial agent which is a di(C8-C18) alkyl di(C1-C4)alkyl ammonium chloride, and (c) 0.1 to 10% by weight of an acidic compound; said composition having a pH of 2-4.
2. A method according to claim 1 wherein the anti-microbial compound content is from 20 to 50 ppm.
3. A method according to claim 1 wherein the lower alcohol comprises the ethanol and the isopropanol in a volume ration of from 1:1 to 1:3.
4. A method according to claim 1 wherein the lower alcohol content is from 20 to 40 % v/v.
5. A method according to claim 1 wherein the acidic compound is a food-grade carboxylic acid or hydroxy acid selected from the group consisting of acetic acid, citric acid, fumaric acid, lactic acid, malic and tartaric acid.
6. A method according to claim 5 wherein the acidic compound is selected from the group consisting of citric acid and lactic acid.
7. A method according to claim 6 wherein the acidic compound content is from 2 to 5 % by weight of the composition.
8. A method according to claim 1 wherein the anti-microbial agent is didecyl dimethyl ammonium chloride.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8604986 | 1986-02-28 | ||
| GB868604986A GB8604986D0 (en) | 1986-02-28 | 1986-02-28 | Disinfectant compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1315196C true CA1315196C (en) | 1993-03-30 |
Family
ID=10593834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000530369A Expired - Fee Related CA1315196C (en) | 1986-02-28 | 1987-02-23 | Method of disinfecting hard surfaces |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA1315196C (en) |
| GB (2) | GB8604986D0 (en) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5139788A (en) * | 1989-10-17 | 1992-08-18 | Ecolab Inc. | Noncontaminating antimicrobial composition |
| GB9024133D0 (en) * | 1990-11-06 | 1990-12-19 | Ici Plc | Aqueous composition |
| DE4225795C2 (en) * | 1992-07-31 | 1994-09-01 | Schuelke & Mayr Gmbh | Disinfectant based on carboxylic acid |
| US5436008A (en) * | 1992-12-11 | 1995-07-25 | Ecolab Inc. | Sanitizing compositions |
| US5683724A (en) * | 1993-03-17 | 1997-11-04 | Ecolab Inc. | Automated process for inhibition of microbial growth in aqueous food transport or process streams |
| US5409713A (en) * | 1993-03-17 | 1995-04-25 | Ecolab Inc. | Process for inhibition of microbial growth in aqueous transport streams |
| FR2708278B1 (en) * | 1993-06-28 | 1995-09-08 | Paragerm Snc | Cleaning and disinfecting composition for hospitals. |
| GB9322132D0 (en) * | 1993-10-27 | 1993-12-15 | Zeneca Ltd | Antimicrobial treatment of textile materials |
| US6302968B1 (en) | 1994-04-19 | 2001-10-16 | Ecolab Inc. | Precarboxylic acid rinse method |
| US5578134A (en) * | 1994-04-19 | 1996-11-26 | Ecolab Inc. | Method of sanitizing and destaining tableware |
| US6257253B1 (en) | 1994-04-19 | 2001-07-10 | Ecolab Inc. | Percarboxylic acid rinse method |
| JP3515821B2 (en) * | 1994-10-21 | 2004-04-05 | 株式会社資生堂 | Disinfecting composition |
| GB9609910D0 (en) * | 1996-05-11 | 1996-07-17 | Applied Chemicals Ltd | Food industry sanitizer composition |
| DE19710256A1 (en) * | 1997-03-13 | 1998-09-17 | Henkel Ecolab Gmbh & Co Ohg | Disinfection procedures |
| FR2766371B1 (en) * | 1997-07-24 | 2000-04-14 | Cair L G L | DISINFECTION, DETERGENCE AND DESCALING PRODUCT FOR MEDICAL EQUIPMENT |
| US7399790B2 (en) | 2001-02-28 | 2008-07-15 | Konowalchuk Thomas W | Virucidal compositions |
| WO2002069887A2 (en) * | 2001-02-28 | 2002-09-12 | Konowalchuk Thomas W | Virucidal compositions |
| AU2004218353C1 (en) | 2003-03-05 | 2011-02-24 | Byocoat Enterprises, Inc. | Antimicrobial solution and process |
| JP2006519841A (en) * | 2003-03-10 | 2006-08-31 | ザンテック ファーマスーティカルズ，インク． | Surface disinfecting composition with improved antibacterial performance |
| US9629361B2 (en) | 2006-02-09 | 2017-04-25 | Gojo Industries, Inc. | Composition and method for pre-surgical skin disinfection |
| US8119115B2 (en) | 2006-02-09 | 2012-02-21 | Gojo Industries, Inc. | Antiviral method |
| MX2008015188A (en) | 2006-05-30 | 2009-03-06 | Dial Corp | Compositions having a high antiviral effeicacy. |
| EP2034831A2 (en) * | 2006-05-31 | 2009-03-18 | The Dial Corporation | Alcohol-containing antimicrobial compositions having improved efficacy |
| RU2431961C2 (en) | 2006-06-02 | 2011-10-27 | Дзе Дайл Корпорейшн | Method of inhibiting transfer of influenza virus |
| RU2008152442A (en) * | 2006-06-05 | 2010-07-20 | Дзей Дайл Корпорейшн (Us) | METHODS AND PRODUCTS HAVING HIGH ANTIVIRAL AND ANTI-BACTERIAL EFFICIENCY |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU513753B2 (en) * | 1974-07-08 | 1980-12-18 | Johnson & Johnson | Antimicrobial composition |
| DE2916318A1 (en) * | 1979-04-23 | 1980-11-06 | Hoechst Ag | AQUEOUS DISINFECTANT SOLUTION |
-
1986
- 1986-02-28 GB GB868604986A patent/GB8604986D0/en active Pending
-
1987
- 1987-02-23 CA CA000530369A patent/CA1315196C/en not_active Expired - Fee Related
- 1987-02-26 GB GB8704581A patent/GB2187097B/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB2187097A (en) | 1987-09-03 |
| GB8604986D0 (en) | 1986-04-09 |
| GB2187097B (en) | 1990-05-23 |
| GB8704581D0 (en) | 1987-04-01 |
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