CA1268121C - .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES - Google Patents

.alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES

Info

Publication number
CA1268121C
CA1268121C CA468153A CA468153A CA1268121C CA 1268121 C CA1268121 C CA 1268121C CA 468153 A CA468153 A CA 468153A CA 468153 A CA468153 A CA 468153A CA 1268121 C CA1268121 C CA 1268121C
Authority
CA
Canada
Prior art keywords
alkyl
psoriasis
treatment
allergic responses
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA468153A
Other languages
French (fr)
Other versions
CA1268121A (en
Inventor
Bernard Loev
Wan-Kit Chan
Howard Jones
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to CA468153A priority Critical patent/CA1268121C/en
Application granted granted Critical
Publication of CA1268121A publication Critical patent/CA1268121A/en
Publication of CA1268121C publication Critical patent/CA1268121C/en
Expired legal-status Critical Current

Links

Abstract

ABSTRACT OF THE DISCLOSURE Polyolefinic compounds represented by the general formula in which R1 are each hydrogen or an alkyl group of from 1 to 5 carbon atoms; R2 is an alkyl group of from 1 to 5 carbon atoms; R3 is hydroxyl, alkoxy of from 1 to 5 carbon atoms, NH2, NHR2 or NR2R2 and Z is cycloalkyl, cycloalkenyl or cycloalkdienyl group substituted with from 0 to 5 alkyl groups, a keto group or a hydroxyl group or a phenyl group substituted with from 0 to 4 hydroxy, alkoxy, alkyl or trifluoromethyl groups or halogen atoms or combinations thereof and the pharmaceutically acceptable salts thereof. The foregoing compounds have been found to be effective in the treatment of psoriasis, inflammatory conditions and allergic responses.
CA468153A 1984-11-19 1984-11-19 .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES Expired CA1268121C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA468153A CA1268121C (en) 1984-11-19 1984-11-19 .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA468153A CA1268121C (en) 1984-11-19 1984-11-19 .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES

Publications (2)

Publication Number Publication Date
CA1268121A CA1268121A (en) 1990-04-24
CA1268121C true CA1268121C (en) 1990-04-24

Family

ID=4129181

Family Applications (1)

Application Number Title Priority Date Filing Date
CA468153A Expired CA1268121C (en) 1984-11-19 1984-11-19 .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES

Country Status (1)

Country Link
CA (1) CA1268121C (en)

Also Published As

Publication number Publication date
CA1268121A (en) 1990-04-24

Similar Documents

Publication Publication Date Title
NO165145C (en) ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1H-IMIDAZO- (4,5-C) -KINOLIN-4-AMINE DERIVATIVES.
ES8800158A1 (en) Ethylenediamine monoamides
ES8507092A1 (en) Alpha-alkyl polyolefinic carboxylic acids and derivatives thereof useful in the treatment of psoriasis.
SE8107273L (en) 2-OXOAZETIDE DERIVATIVES, SET TO PREPARE DEMOCH USE THEREOF
ES523890A0 (en) A PROCEDURE FOR PREPARING PENEM DERIVATIVES.
CA1268121C (en) .alpha.-ALKYL POLYOLEFINIC CARBOXYLIC ACIDS AND DERIVATIVES THEREOF USEFUL IN THE TREATMENT OF PSORIASIS AND ALLERGIC RESPONSES
CA1273946C (en) Anticonvulsant gamma-thiobutyrolactone derivatives
ES2077345T3 (en) INTERMEDIARIES OF THE MUREIDOMICINA GROUP, ITS PREPARATION AND USE.
IL72681A (en) 4-alkyl-5-haloimidazole-1-carboxylic acid esters and amides,their preparation and their use as nitrification inhibitors
AU566668B2 (en) Phenylalkyl (piperazinyl and homopiperazinyl)
ES2019551A6 (en) Process for obtaining derivatives of 6-fluoro-1,4-dihydro-4-oxo-7-piperazinyl-3-quinolinecarboxylic acid and derivatives of acrylate used in said process
ES8303319A1 (en) A procedure to obtain biciclooctan derivatives. (Machine-translation by Google Translate, not legally binding)

Legal Events

Date Code Title Description
MKLA Lapsed
MKLA Lapsed

Effective date: 19941024