CA1255219A - Microspheres marquees par une substance non radioactive et utilisation pour mesurer le debit sanguin - Google Patents

Microspheres marquees par une substance non radioactive et utilisation pour mesurer le debit sanguin

Info

Publication number
CA1255219A
CA1255219A CA000502920A CA502920A CA1255219A CA 1255219 A CA1255219 A CA 1255219A CA 000502920 A CA000502920 A CA 000502920A CA 502920 A CA502920 A CA 502920A CA 1255219 A CA1255219 A CA 1255219A
Authority
CA
Canada
Prior art keywords
microspheres
tissue
set forth
blood
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000502920A
Other languages
English (en)
Inventor
William E. Shell
Jackie R. See
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
See/Shell Biotechnology Inc
Original Assignee
See/Shell Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by See/Shell Biotechnology Inc filed Critical See/Shell Biotechnology Inc
Application granted granted Critical
Publication of CA1255219A publication Critical patent/CA1255219A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A61B5/0275—Measuring blood flow using tracers, e.g. dye dilution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1241—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules particles, powders, lyophilizates, adsorbates, e.g. polymers or resins for adsorption or ion-exchange resins
    • A61K51/1255—Granulates, agglomerates, microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
CA000502920A 1985-02-27 1986-02-27 Microspheres marquees par une substance non radioactive et utilisation pour mesurer le debit sanguin Expired CA1255219A (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/706,151 US4616658A (en) 1985-02-27 1985-02-27 Non-radioactively labeled microspheres and use of same to measure blood flow
US706,151 1985-02-27
AU54320/86A AU580389B2 (en) 1985-02-27 1986-03-05 Non-radioactively labeled microspheres and use of same to measure blood flow

Publications (1)

Publication Number Publication Date
CA1255219A true CA1255219A (fr) 1989-06-06

Family

ID=36889190

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000502920A Expired CA1255219A (fr) 1985-02-27 1986-02-27 Microspheres marquees par une substance non radioactive et utilisation pour mesurer le debit sanguin

Country Status (6)

Country Link
US (2) US4616658A (fr)
EP (1) EP0194517B1 (fr)
JP (1) JPS62221334A (fr)
AU (1) AU580389B2 (fr)
CA (1) CA1255219A (fr)
DE (1) DE3650219T2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4616658A (en) * 1985-02-27 1986-10-14 William Shell Non-radioactively labeled microspheres and use of same to measure blood flow
US5375606A (en) * 1990-02-28 1994-12-27 Zynaxis, Inc. Bio-analytical separation method
DE4019025C2 (de) * 1990-06-14 1994-09-22 Triton Technology Inc Verfahren zur Messung der Durchblutung von Organ- und/oder Gewebeproben
US5687726A (en) * 1991-09-13 1997-11-18 Hoeft; Andreas Process for determining the volume of blood in circulation
US5828712A (en) * 1992-01-13 1998-10-27 General Electric Company Coolant water flow rate test with rubidium nuclear tracer for reactors
US5628328A (en) * 1995-04-25 1997-05-13 Iowa State University Research Foundation Method for measuring muscle mass
US5594179A (en) * 1995-11-06 1997-01-14 Marsh-Mcbirney, Inc. Tracer type flowmeter and method using two or more injected trace materials
US6001333A (en) * 1997-09-12 1999-12-14 See; Jackie R. Methods of preparing micro encapsulated agents for use in the detection of tumors by CT imaging
US6986744B1 (en) 1999-02-02 2006-01-17 Transonic Systems, Inc. Method and apparatus for determining blood flow during a vascular corrective procedure
DE10041052B4 (de) * 2000-08-22 2004-04-29 Metronom Gmbh Industrial Measurements Verfahren zur Bestimmung des Volumens eines Fluids in einem Behälter
US20060290197A1 (en) * 2005-06-10 2006-12-28 See Jackie R Oil extraction system and method
US7568527B2 (en) * 2007-01-04 2009-08-04 Rock Well Petroleum, Inc. Method of collecting crude oil and crude oil collection header apparatus
US7543649B2 (en) * 2007-01-11 2009-06-09 Rock Well Petroleum Inc. Method of collecting crude oil and crude oil collection header apparatus
US7823662B2 (en) 2007-06-20 2010-11-02 New Era Petroleum, Llc. Hydrocarbon recovery drill string apparatus, subterranean hydrocarbon recovery drilling methods, and subterranean hydrocarbon recovery methods
US7832483B2 (en) * 2008-01-23 2010-11-16 New Era Petroleum, Llc. Methods of recovering hydrocarbons from oil shale and sub-surface oil shale recovery arrangements for recovering hydrocarbons from oil shale
GB201018096D0 (en) * 2010-10-27 2010-12-08 Binding Site Group The Ltd Coated beads
WO2017070315A1 (fr) * 2015-10-23 2017-04-27 Geosyntec Consultants, Inc. Utilisation de composés détectables visiblement en tant que composés de référence dans des dispositifs d'échantillonnage passif
KR20180081561A (ko) 2015-11-06 2018-07-16 벤타나 메디컬 시스템즈, 인코포레이티드 대표 진단법

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210406A1 (de) * 1972-03-03 1973-09-06 Siemens Ag Verfahren zur quantitativen messung an fluessigkeiten
US4076419A (en) * 1976-07-12 1978-02-28 Kleker Richard G Method and apparatus for hematology
US4115535A (en) * 1977-06-22 1978-09-19 General Electric Company Diagnostic method employing a mixture of normally separable protein-coated particles
US4294259A (en) * 1977-11-25 1981-10-13 Bios Inc. Method and apparatus for characterizing blood flow through the heart
CA1157373A (fr) * 1980-01-04 1983-11-22 Harris Busch Detection de cellules cancereuses humaines a l'aide d'anticorps contre les antigenes nucleolaires de cancers humains
US4676252A (en) * 1981-06-05 1987-06-30 Massachusetts General Hospital Double indicator pulmonary edema measurement
US4417588A (en) * 1982-03-22 1983-11-29 Critikon, Inc. Apparatus and method for initiating cardiac output computations
DE3322373C2 (de) * 1983-05-19 1986-12-04 Ioannis Dr. 3000 Hannover Tripatzis Testmittel und Verfahren zum Nachweis von Antigenen und/oder Antikörpern
US4616658A (en) * 1985-02-27 1986-10-14 William Shell Non-radioactively labeled microspheres and use of same to measure blood flow

Also Published As

Publication number Publication date
US4616658A (en) 1986-10-14
AU580389B2 (en) 1989-01-12
DE3650219D1 (de) 1995-03-16
JPS62221334A (ja) 1987-09-29
AU5432086A (en) 1987-09-10
US4811741A (en) 1989-03-14
DE3650219T2 (de) 1995-05-24
EP0194517A1 (fr) 1986-09-17
EP0194517B1 (fr) 1995-02-01

Similar Documents

Publication Publication Date Title
CA1255219A (fr) Microspheres marquees par une substance non radioactive et utilisation pour mesurer le debit sanguin
Krawisz et al. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity: assessment of inflammation in rat and hamster models
Atyabi et al. In vivo evaluation of a novel gastric retentive formulation based on ion exchange resins
Scheffel et al. Albumin microspheres for study of the reticuloendothelial system
Thompson et al. Size dependent platelet subpopulations: relationship of platelet volume to ultrastructure, enzymatic activity, and function
Goodman et al. Electron microscopy of formed elements of normal human blood
Hale et al. Evaluation of nonradioactive, colored microspheres for measurement of regional myocardial blood flow in dogs.
Daniel et al. Quantitation of chemically induced DNA strand breaks in human cells via an alkaline unwinding assay
EP0166755B1 (fr) Agent de contraste et de diagnostic
Cavill et al. The measurement of the total volume of red cells in man: a non‐radioactive approach using biotin
Zubroff et al. A nonradioactive method for measuring DNA damage and its repair in nonproliferating tissues
Hellman et al. Alkaline single cell gel electrophoresis of DNA fragments in biomonitoring for genotoxicity: an introductory study on healthy human volunteers
Bentley et al. A method for the investigation of reticuloendothelial iron kinetics in man
US5230343A (en) Colored microspheres for measuring and tracing fluid mixing and flow
Kudo et al. Validation of in vivo receptor measurements via in vitro radioassay: technetium-99m-galactosyl-neoglycoalbumin as prototype model
Rosenfield et al. Nonuniform distribution of occult blood in feces
Iozzo et al. Immunoelectron microscopic localization of catalase in human eosinophilic leukocytes.
Collste et al. Identification of polymorphonuclear leukocytes in cytologic samples for flow cytometry.
Krieg et al. Superparamagnetically labelled neutrophils as potential abscess-specific contrast agent for MRI
Schauwecker et al. Comparison of purified indium-111 granulocytes and indium-111 mixed leukocytes for imaging of infections
DE69013730T2 (de) Für ganze Zellen geeigneter Satz und Verfahren zu enzymatischen Bestimmungen.
Marsh et al. Radioimmunoassay of drugs of abuse in hair. Part 1: Methadone in human hair, method adaptation and the evaluation of decontamination procedures
McELLIGOTT et al. Erythrocyte-mediated microinjection, a technique to study protein degradation in muscle cells
Agnew et al. Protein binding of tellurium-127m by maternal and fetal tissues of the rat
Russell et al. Method for the quantitation of gastric emptying time of gel test meals

Legal Events

Date Code Title Description
MKEX Expiry