CA1189074A - Nitroimidazole derivatives - Google Patents

Nitroimidazole derivatives

Info

Publication number
CA1189074A
CA1189074A CA000396880A CA396880A CA1189074A CA 1189074 A CA1189074 A CA 1189074A CA 000396880 A CA000396880 A CA 000396880A CA 396880 A CA396880 A CA 396880A CA 1189074 A CA1189074 A CA 1189074A
Authority
CA
Canada
Prior art keywords
nitroimidazole
methyl
platinum
bis
dichloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000396880A
Other languages
English (en)
French (fr)
Inventor
Christopher J. Coulson
Peter J. Sadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
May and Baker Ltd
Original Assignee
May and Baker Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by May and Baker Ltd filed Critical May and Baker Ltd
Application granted granted Critical
Publication of CA1189074A publication Critical patent/CA1189074A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91Nitro radicals
    • C07D233/92Nitro radicals attached in position 4 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000396880A 1981-02-24 1982-02-23 Nitroimidazole derivatives Expired CA1189074A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8105759 1981-02-24
GB8105759 1981-02-24
GB8119766 1981-06-26
GB8119766 1981-06-26
GB8135397 1981-11-24
GB8135397 1981-11-24

Publications (1)

Publication Number Publication Date
CA1189074A true CA1189074A (en) 1985-06-18

Family

ID=27261120

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000396880A Expired CA1189074A (en) 1981-02-24 1982-02-23 Nitroimidazole derivatives

Country Status (13)

Country Link
AU (1) AU8065082A (it)
CA (1) CA1189074A (it)
CH (1) CH654315A5 (it)
DE (1) DE3206610A1 (it)
DK (1) DK76382A (it)
FI (1) FI820569L (it)
FR (1) FR2500449B1 (it)
GR (1) GR74776B (it)
IE (1) IE52557B1 (it)
IT (1) IT1195782B (it)
LU (1) LU83968A1 (it)
NL (1) NL8200712A (it)
SE (1) SE8201100L (it)

Also Published As

Publication number Publication date
IT1195782B (it) 1988-10-27
FR2500449A1 (fr) 1982-08-27
FI820569A7 (fi) 1982-08-25
DK76382A (da) 1982-08-25
FR2500449B1 (fr) 1985-10-04
AU8065082A (en) 1982-09-02
GR74776B (it) 1984-07-12
LU83968A1 (fr) 1982-12-13
FI820569L (fi) 1982-08-25
NL8200712A (nl) 1982-09-16
DE3206610A1 (de) 1982-10-07
IT8219842A0 (it) 1982-02-24
CH654315A5 (fr) 1986-02-14
SE8201100L (sv) 1982-08-25
IE52557B1 (en) 1987-12-09
IE820359L (en) 1982-08-24

Similar Documents

Publication Publication Date Title
Kovala-Demertzi et al. In vitro and in vivo antitumor activity of platinum (II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N (4)-position: synthesis, spectroscopic study and crystal structure of platinum (II) complexes with thiosemicarbazones, potential anticancer agents
US5426203A (en) Platinum complexes of malonic acid derivatives and process for the preparation thereof
JPWO1991009041A1 (ja) 新規白金(2)錯体および悪性腫瘍治療剤
US5100885A (en) Copper radiosensitizers
US4607114A (en) Novel platinum complexes
EP0095906B1 (en) Improvements relating to compounds useful in radiotherapy or chemotherapy
EP0273315B1 (en) Ammine-n-heterocyclic-platinum complexes and antitumor agents
GB2093451A (en) Nitroimidazole derivatives
EP0202673B1 (de) Cytostatisch wirksame Titanocen-Komplexe
CA1189074A (en) Nitroimidazole derivatives
EP1558620A1 (en) Ruthenium anticancer complexes
DE60105028T2 (de) Ruthenium (ii) verbindungen in der krebsbehandlung
EP0176005B1 (en) Novel platinum complexes
GB2131020A (en) Bis(nitro-1-imidazolyl alkylamine) platinum complexes useful in radiotherapy or chemotherapy
GB2122194A (en) New metal complexes of nitro- substituted pyrazoles, imidazoles and isothiazoles
CA2070497C (en) Novel platinum (ii) complex and antitumor agent
US3455926A (en) Phenazine derivatives
CA1281327C (en) Anti-tumour platinum complexes, their preparation and their use
US5616613A (en) Platinum(II) complex and malignant tumor treatment agent
US5116831A (en) Aminoalkyl-substituted cycloalkylamine platinum (II) complexes
US4463006A (en) Diglycidyl-pteridine compounds
US5498780A (en) Platinum complex and malignant tumor treating drug containing the same
RU2024514C1 (ru) Комплекс 1-этилимидазола с аскорбатом цинка, повышающий устойчивость организма к действию диоксида азота и обладающий цитопротекторным и антигипоксическим действием
JPS5931792A (ja) 複素環の新規な金属錯体
Booysen Rhenium (V)-Imido complexes with potentially multidentate ligands containing the amino group

Legal Events

Date Code Title Description
MKEX Expiry