CA1178269A - Test d'immunofluorescence-polarisation utilisant des carboxyfluoresceines substituees - Google Patents

Test d'immunofluorescence-polarisation utilisant des carboxyfluoresceines substituees

Info

Publication number
CA1178269A
CA1178269A CA000396311A CA396311A CA1178269A CA 1178269 A CA1178269 A CA 1178269A CA 000396311 A CA000396311 A CA 000396311A CA 396311 A CA396311 A CA 396311A CA 1178269 A CA1178269 A CA 1178269A
Authority
CA
Canada
Prior art keywords
compound according
derived
ligand
drug
tracer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000396311A
Other languages
English (en)
Inventor
Chao-Huei J. Wang
Stephen D. Stroupe
Michael E. Jolley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of CA1178269A publication Critical patent/CA1178269A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA000396311A 1981-02-17 1982-02-16 Test d'immunofluorescence-polarisation utilisant des carboxyfluoresceines substituees Expired CA1178269A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23525981A 1981-02-17 1981-02-17
US235,259 1981-02-17
US32997481A 1981-12-11 1981-12-11
US329,974 1981-12-11

Publications (1)

Publication Number Publication Date
CA1178269A true CA1178269A (fr) 1984-11-20

Family

ID=26928739

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000396311A Expired CA1178269A (fr) 1981-02-17 1982-02-16 Test d'immunofluorescence-polarisation utilisant des carboxyfluoresceines substituees

Country Status (3)

Country Link
CA (1) CA1178269A (fr)
DE (1) DE3205506C2 (fr)
NZ (1) NZ199629A (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476228A (en) * 1982-11-08 1984-10-09 Abbott Laboratories Determination of unsaturated thyroxine binding protein sites using fluorescence polarization techniques
US4476229A (en) * 1982-11-08 1984-10-09 Abbott Laboratories Substituted carboxyfluoresceins
CA1195995A (fr) * 1982-11-08 1985-10-29 Curtis L. Kirkemo Carboxyfluoresceines substituees
US4698315A (en) * 1985-04-22 1987-10-06 Hoffmann-La Roche Inc. Method and kit for determining total digoxin levels involving agent to dissociate digoxin-protein complex
EP0226730B1 (fr) * 1985-10-15 1994-03-02 Abbott Laboratories Composés et essai immunologique pour antidépressifs tricycliques
US5017474A (en) * 1988-02-12 1991-05-21 Eastman Kodak Company Wash solution, test kit and method for the determination of an immunological ligand
US5284948A (en) * 1991-06-07 1994-02-08 Eastman Kodak Company Drug hapten analogues for immunoassays
ATE204384T1 (de) * 1991-06-07 2001-09-15 Johnson & Johnson Clin Diag Markierte hapten-analoge zur verwendung in immunoassays
DE69232002T2 (de) * 1991-06-07 2002-06-06 Johnson & Johnson Clin Diag Immunoassays unter Verwendung von markierten Hapten-Analogen
ATE176329T1 (de) * 1992-06-26 1999-02-15 Johnson & Johnson Clin Diag Immunotests unter verwendung von markierten thyronin-analogen
US5315015A (en) * 1992-11-10 1994-05-24 Hoffmann-La Roche Inc. Compounds having improved fluorescence in fluorescence polarization immunoassays and immunoassays utilizing same
DE10032633A1 (de) * 2000-07-05 2002-01-17 Bayer Ag Verfahren zum Auffinden von Hemmstoffen der Protoporphyrinogen-Oxidase

Also Published As

Publication number Publication date
DE3205506A1 (de) 1982-09-16
DE3205506C2 (de) 1996-10-10
NZ199629A (en) 1984-11-09

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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry