CA1176242A - Bis-esters of alkanediols as antibacterial agents - Google Patents

Bis-esters of alkanediols as antibacterial agents

Info

Publication number
CA1176242A
CA1176242A CA000396680A CA396680A CA1176242A CA 1176242 A CA1176242 A CA 1176242A CA 000396680 A CA000396680 A CA 000396680A CA 396680 A CA396680 A CA 396680A CA 1176242 A CA1176242 A CA 1176242A
Authority
CA
Canada
Prior art keywords
alpha
methyl
beta
penam
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000396680A
Other languages
English (en)
French (fr)
Inventor
Wayne E. Barth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd Great Britain
Original Assignee
Pfizer Ltd Great Britain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd Great Britain filed Critical Pfizer Ltd Great Britain
Application granted granted Critical
Publication of CA1176242A publication Critical patent/CA1176242A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA000396680A 1981-02-20 1982-02-19 Bis-esters of alkanediols as antibacterial agents Expired CA1176242A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/236,407 US4364957A (en) 1979-09-26 1981-02-20 Bis-esters of alkanediols as antibacterial agents
US236,407 1981-02-20

Publications (1)

Publication Number Publication Date
CA1176242A true CA1176242A (en) 1984-10-16

Family

ID=22889370

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000396680A Expired CA1176242A (en) 1981-02-20 1982-02-19 Bis-esters of alkanediols as antibacterial agents

Country Status (11)

Country Link
US (1) US4364957A (https=)
EP (1) EP0059046B1 (https=)
JP (1) JPS57154192A (https=)
AT (1) ATE15044T1 (https=)
AU (1) AU527894B2 (https=)
CA (1) CA1176242A (https=)
DE (1) DE3265503D1 (https=)
DK (1) DK72282A (https=)
ES (1) ES8304992A1 (https=)
GR (1) GR75173B (https=)
IE (1) IE52902B1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4478748A (en) * 1981-02-20 1984-10-23 Pfizer Inc. Bis-esters of alkanediols
US4530792A (en) * 1982-11-01 1985-07-23 Pfizer Inc. Process and intermediates for preparation of 1,1-dioxopenicillanoyloxymethyl 6-beta-aminopenicillanate
US4462934A (en) 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
JPS60214792A (ja) * 1984-04-06 1985-10-28 Taiho Yakuhin Kogyo Kk ペナム酸エステル誘導体
CN104650119B (zh) * 2015-02-10 2017-04-05 中国科学院长春应用化学研究所 一种β‑内酰胺化合物的制备方法
IT202000031070A1 (it) 2020-12-16 2022-06-16 Paolo Bonomi Procedimento di sintesi di derivati ammidici dell’acido 8-idrossi penicillanico

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234579A (en) * 1977-06-07 1980-11-18 Pfizer Inc. Penicillanic acid 1,1-dioxides as β-lactamase inhibitors
US4325960A (en) * 1979-02-13 1982-04-20 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) 6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor
IE49881B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
KR830001903B1 (ko) 1979-02-13 1983-09-19 레오 파마슈티칼 프로덕츠 리미티드 페니실란산유도체의 제조방법
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
US4256733A (en) * 1979-09-26 1981-03-17 Pfizer Inc. Acetoxymethyl penam compounds as β-lactamase inhibitors

Also Published As

Publication number Publication date
DE3265503D1 (en) 1985-09-26
AU527894B2 (en) 1983-03-31
ES509782A0 (es) 1983-03-16
IE820342L (en) 1982-08-20
GR75173B (https=) 1984-07-13
EP0059046A1 (en) 1982-09-01
ES8304992A1 (es) 1983-03-16
ATE15044T1 (de) 1985-09-15
DK72282A (da) 1982-08-21
IE52902B1 (en) 1988-04-13
JPS57154192A (en) 1982-09-22
EP0059046B1 (en) 1985-08-21
US4364957A (en) 1982-12-21
JPS6330312B2 (https=) 1988-06-17
AU8062382A (en) 1982-11-04

Similar Documents

Publication Publication Date Title
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Legal Events

Date Code Title Description
MKEC Expiry (correction)
MKEX Expiry