CA1128883A - Flavin adenine dinucleotide - labeled conjugates for use in specific binding assays - Google Patents

Flavin adenine dinucleotide - labeled conjugates for use in specific binding assays

Info

Publication number
CA1128883A
CA1128883A CA330,232A CA330232A CA1128883A CA 1128883 A CA1128883 A CA 1128883A CA 330232 A CA330232 A CA 330232A CA 1128883 A CA1128883 A CA 1128883A
Authority
CA
Canada
Prior art keywords
conjugate
ligand
beta
specifically bindable
labeled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA330,232A
Other languages
English (en)
French (fr)
Inventor
Robert J. Carrico
Richard D. Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/917,962 external-priority patent/US4171432A/en
Priority claimed from US05/950,858 external-priority patent/US4213893A/en
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Priority to CA000390187A priority Critical patent/CA1137981A/en
Priority to CA000390186A priority patent/CA1139303A/en
Application granted granted Critical
Publication of CA1128883A publication Critical patent/CA1128883A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA330,232A 1978-06-22 1979-06-21 Flavin adenine dinucleotide - labeled conjugates for use in specific binding assays Expired CA1128883A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA000390187A CA1137981A (en) 1978-06-22 1981-11-16 6-(.omega.-AMINOALKYL)-9-(2',3'-O-ISOPROPYLIDINE- .beta.-D-RIBOFURANOSYL)PURINES
CA000390186A CA1139303A (en) 1978-06-22 1981-11-16 Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US917,962 1978-06-22
US05/917,962 US4171432A (en) 1978-06-22 1978-06-22 Flavin adenine dinucleotide-iodothyronine conjugates
US950,858 1978-10-12
US05/950,858 US4213893A (en) 1978-10-12 1978-10-12 Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays

Publications (1)

Publication Number Publication Date
CA1128883A true CA1128883A (en) 1982-08-03

Family

ID=27129736

Family Applications (1)

Application Number Title Priority Date Filing Date
CA330,232A Expired CA1128883A (en) 1978-06-22 1979-06-21 Flavin adenine dinucleotide - labeled conjugates for use in specific binding assays

Country Status (5)

Country Link
CA (1) CA1128883A (xx)
DE (1) DE2924332A1 (xx)
FR (1) FR2429223A1 (xx)
GB (3) GB2041919B (xx)
IL (1) IL57571A (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64813A (en) * 1981-03-23 1984-11-30 Miles Lab Activated apoglucose oxidase and its use in specific binding assays
CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US7220854B1 (en) 1982-06-23 2007-05-22 Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
FR2556726B1 (fr) * 1983-12-20 1987-02-20 California Inst Of Techn Compositions a base d'oligonucleotides monocatenaires et procede pour leur preparation
GB9823646D0 (en) 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN142734B (xx) * 1975-04-28 1977-08-20 Miles Lab

Also Published As

Publication number Publication date
FR2429223A1 (fr) 1980-01-18
FR2429223B1 (xx) 1983-01-14
DE2924332A1 (de) 1980-01-03
DE2924332C2 (xx) 1989-03-23
IL57571A0 (en) 1979-10-31
GB2041919A (en) 1980-09-17
GB2040943B (en) 1983-01-26
GB2041919B (en) 1982-08-11
GB2023609B (en) 1982-10-20
GB2023609A (en) 1980-01-03
GB2040943A (en) 1980-09-03
IL57571A (en) 1983-03-31

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Legal Events

Date Code Title Description
MKEX Expiry
MKEX Expiry

Effective date: 19990803