GB2041919B - Amino-purine intermediates useful in the preparation of flavin adenine dinucleotide-labelled conjugates for use in specific binding assays - Google Patents

Amino-purine intermediates useful in the preparation of flavin adenine dinucleotide-labelled conjugates for use in specific binding assays

Info

Publication number
GB2041919B
GB2041919B GB7941830A GB7941830A GB2041919B GB 2041919 B GB2041919 B GB 2041919B GB 7941830 A GB7941830 A GB 7941830A GB 7941830 A GB7941830 A GB 7941830A GB 2041919 B GB2041919 B GB 2041919B
Authority
GB
United Kingdom
Prior art keywords
amino
preparation
specific binding
binding assays
adenine dinucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7941830A
Other versions
GB2041919A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/917,962 external-priority patent/US4171432A/en
Priority claimed from US05/950,858 external-priority patent/US4213893A/en
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of GB2041919A publication Critical patent/GB2041919A/en
Application granted granted Critical
Publication of GB2041919B publication Critical patent/GB2041919B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/535Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
GB7941830A 1978-06-22 1979-06-21 Amino-purine intermediates useful in the preparation of flavin adenine dinucleotide-labelled conjugates for use in specific binding assays Expired GB2041919B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/917,962 US4171432A (en) 1978-06-22 1978-06-22 Flavin adenine dinucleotide-iodothyronine conjugates
US05/950,858 US4213893A (en) 1978-10-12 1978-10-12 Flavin adenine dinucleotide-labeled conjugates for use in specific binding assays

Publications (2)

Publication Number Publication Date
GB2041919A GB2041919A (en) 1980-09-17
GB2041919B true GB2041919B (en) 1982-08-11

Family

ID=27129736

Family Applications (3)

Application Number Title Priority Date Filing Date
GB7941829A Expired GB2040943B (en) 1978-06-22 1979-06-21 Intermediates useful in the preparation of flavin adenine dinucleotide - labeled conjugates for use in specific binding assays
GB7921694A Expired GB2023609B (en) 1978-06-22 1979-06-21 Flavin-adenine-dinulcleotide derivatives for use in specific binding assays
GB7941830A Expired GB2041919B (en) 1978-06-22 1979-06-21 Amino-purine intermediates useful in the preparation of flavin adenine dinucleotide-labelled conjugates for use in specific binding assays

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB7941829A Expired GB2040943B (en) 1978-06-22 1979-06-21 Intermediates useful in the preparation of flavin adenine dinucleotide - labeled conjugates for use in specific binding assays
GB7921694A Expired GB2023609B (en) 1978-06-22 1979-06-21 Flavin-adenine-dinulcleotide derivatives for use in specific binding assays

Country Status (5)

Country Link
CA (1) CA1128883A (en)
DE (1) DE2924332A1 (en)
FR (1) FR2429223A1 (en)
GB (3) GB2040943B (en)
IL (1) IL57571A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL64813A (en) * 1981-03-23 1984-11-30 Miles Lab Activated apoglucose oxidase and its use in specific binding assays
CA1223831A (en) 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
US7220854B1 (en) 1982-06-23 2007-05-22 Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
FR2556726B1 (en) * 1983-12-20 1987-02-20 California Inst Of Techn COMPOSITIONS BASED ON SINGLE-STRANDED OLIGONUCLEOTIDES AND PROCESS FOR THEIR PREPARATION
GB9823646D0 (en) 1997-12-19 1998-12-23 Brax Genomics Ltd Compounds for mass spectrometry

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN142734B (en) * 1975-04-28 1977-08-20 Miles Lab

Also Published As

Publication number Publication date
CA1128883A (en) 1982-08-03
DE2924332C2 (en) 1989-03-23
GB2040943B (en) 1983-01-26
GB2023609B (en) 1982-10-20
DE2924332A1 (en) 1980-01-03
FR2429223B1 (en) 1983-01-14
GB2041919A (en) 1980-09-17
GB2023609A (en) 1980-01-03
GB2040943A (en) 1980-09-03
IL57571A0 (en) 1979-10-31
FR2429223A1 (en) 1980-01-18
IL57571A (en) 1983-03-31

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960621