CA1112644A - Dioxopyranoquinoline dicarboxylic acid derivatives - Google Patents

Dioxopyranoquinoline dicarboxylic acid derivatives

Info

Publication number
CA1112644A
CA1112644A CA302,479A CA302479A CA1112644A CA 1112644 A CA1112644 A CA 1112644A CA 302479 A CA302479 A CA 302479A CA 1112644 A CA1112644 A CA 1112644A
Authority
CA
Canada
Prior art keywords
compound
formula
group
dioxo
quinoline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA302,479A
Other languages
English (en)
French (fr)
Inventor
David Cox
Hugh Cairns
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Ltd filed Critical Fisons Ltd
Application granted granted Critical
Publication of CA1112644A publication Critical patent/CA1112644A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
CA302,479A 1977-05-04 1978-05-02 Dioxopyranoquinoline dicarboxylic acid derivatives Expired CA1112644A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB18597/77 1977-05-04
GB1859777 1977-05-04
GB4586577 1977-11-04
GB45865/77 1977-11-04

Publications (1)

Publication Number Publication Date
CA1112644A true CA1112644A (en) 1981-11-17

Family

ID=26253475

Family Applications (1)

Application Number Title Priority Date Filing Date
CA302,479A Expired CA1112644A (en) 1977-05-04 1978-05-02 Dioxopyranoquinoline dicarboxylic acid derivatives

Country Status (16)

Country Link
JP (2) JPS53137969A (no)
AU (1) AU520816B2 (no)
CA (1) CA1112644A (no)
CH (1) CH634071A5 (no)
DE (1) DE2819215A1 (no)
DK (1) DK158266C (no)
ES (1) ES469391A1 (no)
FR (1) FR2389627B1 (no)
IE (1) IE47051B1 (no)
IL (2) IL54614A (no)
IT (1) IT1158699B (no)
LU (2) LU79579A1 (no)
NL (2) NL184896C (no)
NO (1) NO154497C (no)
NZ (1) NZ187156A (no)
SE (2) SE443561B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760072A (en) * 1984-04-13 1988-07-26 Fisons, Plc Solid nedocromil sodium, useful for the removal of obstructed air pathways

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2440371A1 (fr) * 1978-10-31 1980-05-30 Fisons Ltd Nouveaux composes azotes heterocycliques, des compositions pharmaceutiques en contenant et des procedes pour les preparer
DE3070179D1 (en) * 1979-12-07 1985-03-28 Fisons Plc A process for the production of 1,4-dihydro-4-oxo-quinoline-2-carboxylic acids, or salts, esters or amides thereof and intermediates therefor
ES2058129T3 (es) * 1986-12-23 1994-11-01 Fisons Plc Composiciones farmaceuticas que comprenden una solucion acuosa de un derivado de piranoquinolina.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2054503A1 (en) * 1969-07-18 1971-04-23 Bellon Labor Sa Roger 1, 4-dihydro-4-oxo quinolyl-3-carboxylic aci

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760072A (en) * 1984-04-13 1988-07-26 Fisons, Plc Solid nedocromil sodium, useful for the removal of obstructed air pathways
EP0162556B1 (en) * 1984-04-13 1991-11-06 FISONS plc Novels forms and formulations of nedocromil sodium

Also Published As

Publication number Publication date
DE2819215C2 (no) 1990-12-13
SE8602492L (sv) 1986-06-02
NO154497B (no) 1986-06-23
LU88281I2 (fr) 1994-05-04
JPS53137969A (en) 1978-12-01
NZ187156A (en) 1984-03-30
DK158266B (da) 1990-04-23
NL184896C (nl) 1989-12-01
DK190178A (da) 1978-11-05
CH634071A5 (en) 1983-01-14
IL54614A (en) 1983-07-31
IL54614A0 (en) 1978-07-31
IE780890L (en) 1978-11-04
IL61826A0 (en) 1981-01-30
IT7822918A0 (it) 1978-05-02
NL930050I2 (nl) 1993-11-16
LU79579A1 (fr) 1979-02-02
JPH0122276B2 (no) 1989-04-25
AU3573178A (en) 1979-11-08
AU520816B2 (en) 1982-03-04
FR2389627A1 (no) 1978-12-01
SE443561B (sv) 1986-03-03
NL184896B (nl) 1989-07-03
ES469391A1 (es) 1979-10-01
SE8602492D0 (sv) 1986-06-02
IT1158699B (it) 1987-02-25
NO781549L (no) 1978-11-07
FR2389627B1 (no) 1981-01-02
SE463920B (sv) 1991-02-11
IE47051B1 (en) 1983-12-14
JPH01199909A (ja) 1989-08-11
DE2819215A1 (de) 1978-11-16
NL7804749A (nl) 1978-11-07
SE7805105L (sv) 1978-11-05
NL930050I1 (nl) 1993-09-01
NO154497C (no) 1986-10-01
DK158266C (da) 1990-10-08

Similar Documents

Publication Publication Date Title
EP0264586B1 (en) Hydantoin derivatives for treating complications of diabetes
US4474787A (en) 7,6 Dioxo-4H,6H-pyrano[3,2-g]quinoline dicarboxylic acids and anti-allergic use thereof
EP0300614B1 (en) Process for the preparation of substituted indolinone derivatives
CA1300626C (en) Dihydropyridine compounds, processes for their preparation and their use
Hauser et al. A new procedure for regiospecific syntheses of benzopyran-1-ones
CA1112644A (en) Dioxopyranoquinoline dicarboxylic acid derivatives
Brimble et al. Synthesis of the cis-3a, 8b-dihydrofuro [3, 2-b] benzofuran-2 (3 H)-one ring system via a furofuran annulation to activated benzoquinones
CA1327202C (en) Substituted 1,3,4,9-tetrahydropyrano ¬3,4-b|indole-1-acetic acids
Burke et al. The structure of cleomeolide, an unusual bicyclic diterpene from Cleome viscosa L.(Capparaceae)
US4698345A (en) Quinoline derivatives and their use as anti-asthmatic agents
HU228986B1 (en) Process to produce 4-hydroxy-2-oxo-pyrane derivatives useful as protease inhibitors
Morel et al. New coumarins from Mesua racemosa: Isolation and synthesis
Bongui et al. Synthesis and cytotoxic activity of acronycine analogues in the benzo [c] pyrano [3, 2-h] acridin-7-one and naphtho [1, 2-b][1, 7] and [1, 10]-phenanthrolin-7 (14H)-one series
US4427686A (en) Pharmacologically active benzopyranotriazole compounds
EP0150966B1 (en) Benzopyran derivatives, compositions containing them and processes for their preparation
Anderson et al. Vinylogous carbinolamine tumor inhibitors. 14. 1, 3-dipolar cycloaddition reactions with tetrafluoroborate and trifluoromethanesulfonate salts of 1, 2-dihydro-and 1, 2, 3, 4-tetrahydroquinoline reissert compounds
Narkhede et al. Synthesis of (±)-neorautane
Arrault et al. A Straightforward Synthesis of 1, 2-Dihydronaphtho [2, 1-b] furans from 2-Naphthols
EP0094769A1 (en) Preparing 7-alkoxybenzofurans and intermediates used therein
EP0008610B1 (en) Furonaphthyridine compounds, process for their preparation and pharmaceutical compositions containing them
EP0003084B1 (en) Spirobenzofuranone compounds, processes for their preparation and their use as medicines
US4228173A (en) Thiopyrano-benzopyrans, compositions and method of use thereof
Okabayashi et al. Synthesis of benzothiopyrano [4, 3, 2‐de] quinoline
CA1250584A (en) Benzopyrans
Croisy-Delcey et al. Synthesis of 1-functionalized 5-methylnaphtho [2, 3-g] isoquinoline-6, 11-quinones

Legal Events

Date Code Title Description
MKEX Expiry