CA1088517A - 3-heterothiomethylureidocephalosporines - Google Patents

3-heterothiomethylureidocephalosporines

Info

Publication number
CA1088517A
CA1088517A CA271,818A CA271818A CA1088517A CA 1088517 A CA1088517 A CA 1088517A CA 271818 A CA271818 A CA 271818A CA 1088517 A CA1088517 A CA 1088517A
Authority
CA
Canada
Prior art keywords
amino
methyl
lower alkyl
phenyl
thio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA271,818A
Other languages
English (en)
Inventor
Hermann Breuer
Uwe D. Treuner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/664,795 external-priority patent/US4088815A/en
Priority claimed from US05/664,796 external-priority patent/US4088816A/en
Priority claimed from US05/764,134 external-priority patent/US4127716A/en
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Application granted granted Critical
Publication of CA1088517A publication Critical patent/CA1088517A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA271,818A 1976-03-08 1977-02-15 3-heterothiomethylureidocephalosporines Expired CA1088517A (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US664,796 1976-03-08
US05/664,795 US4088815A (en) 1974-09-20 1976-03-08 3-Heterothio-7-ureido cephalosporins
US664,795 1976-03-08
US05/664,796 US4088816A (en) 1974-09-20 1976-03-08 3-Heterothio substituted 7-(ureido-heteroacetyl) cephalosporins
US05/764,134 US4127716A (en) 1976-03-08 1977-02-02 3-heterothiomethyl ureido cephalosporins
US764,134 1977-02-02

Publications (1)

Publication Number Publication Date
CA1088517A true CA1088517A (fr) 1980-10-28

Family

ID=27418117

Family Applications (1)

Application Number Title Priority Date Filing Date
CA271,818A Expired CA1088517A (fr) 1976-03-08 1977-02-15 3-heterothiomethylureidocephalosporines

Country Status (16)

Country Link
JP (1) JPS52108996A (fr)
AT (1) AT352876B (fr)
AU (1) AU2236777A (fr)
CA (1) CA1088517A (fr)
CS (1) CS191190B2 (fr)
DD (1) DD129793A5 (fr)
DE (1) DE2707812A1 (fr)
DK (1) DK97077A (fr)
ES (1) ES456591A1 (fr)
FR (1) FR2343745A2 (fr)
GB (1) GB1573786A (fr)
NL (1) NL7702405A (fr)
NZ (1) NZ183332A (fr)
PL (1) PL196501A1 (fr)
PT (1) PT66272B (fr)
SE (1) SE7702558L (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927534A1 (de) * 1979-07-07 1981-01-08 Bayer Ag Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
GB1573786A (en) 1980-08-28
ATA155177A (de) 1979-03-15
NL7702405A (nl) 1977-09-12
DE2707812A1 (de) 1977-09-15
JPS52108996A (en) 1977-09-12
ES456591A1 (es) 1978-02-16
PT66272A (fr) 1977-03-31
NZ183332A (en) 1979-10-25
DK97077A (da) 1977-09-09
PT66272B (fr) 1978-08-08
AT352876B (de) 1979-10-10
CS191190B2 (en) 1979-06-29
SE7702558L (sv) 1977-09-09
PL196501A1 (pl) 1978-02-13
DD129793A5 (de) 1978-02-08
FR2343745A2 (fr) 1977-10-07
AU2236777A (en) 1978-08-24

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Legal Events

Date Code Title Description
MKEX Expiry
MKEX Expiry

Effective date: 19971028