CA1082686A - Novel d-homosteroids - Google Patents

Novel d-homosteroids

Info

Publication number
CA1082686A
CA1082686A CA265,305A CA265305A CA1082686A CA 1082686 A CA1082686 A CA 1082686A CA 265305 A CA265305 A CA 265305A CA 1082686 A CA1082686 A CA 1082686A
Authority
CA
Canada
Prior art keywords
beta
group
alpha
methyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA265,305A
Other languages
English (en)
French (fr)
Inventor
Andor Furst
Marcel Muller
Ulrich Kerb
Rudolf Wiechert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1456475A external-priority patent/CH616436A5/de
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1082686A publication Critical patent/CA1082686A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • C07J21/006Ketals at position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA265,305A 1975-11-11 1976-11-10 Novel d-homosteroids Expired CA1082686A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1456475A CH616436A5 (en) 1975-11-11 1975-11-11 Process for the preparation of D-homosteroids.
CH14564/75 1975-11-11
CH11604/76 1976-09-13
CH1160476 1976-09-13

Publications (1)

Publication Number Publication Date
CA1082686A true CA1082686A (en) 1980-07-29

Family

ID=25708627

Family Applications (1)

Application Number Title Priority Date Filing Date
CA265,305A Expired CA1082686A (en) 1975-11-11 1976-11-10 Novel d-homosteroids

Country Status (20)

Country Link
JP (1) JPS5259148A (ja)
AT (1) AT354653B (ja)
AU (1) AU505624B2 (ja)
CA (1) CA1082686A (ja)
DD (1) DD128852A5 (ja)
DE (1) DE2651364A1 (ja)
ES (2) ES461325A1 (ja)
FR (1) FR2331329A1 (ja)
GB (1) GB1564144A (ja)
GR (1) GR70298B (ja)
IE (1) IE43985B1 (ja)
IL (1) IL50854A (ja)
LU (1) LU76161A1 (ja)
MC (1) MC1121A1 (ja)
NL (1) NL7612538A (ja)
NZ (1) NZ182539A (ja)
PH (1) PH13603A (ja)
PL (1) PL193604A1 (ja)
PT (1) PT65821B (ja)
SU (1) SU679147A3 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4788218A (en) * 1984-05-21 1988-11-29 Sri International 17 a β-hydroxy-7 α-methyl-d-homo-19-norandrost-4,16-diene-3-one and the 17-esters thereof: methods of preparation and uses
GB2362648A (en) * 2000-05-23 2001-11-28 Univerzita Palackeho V Olomouc Triterpenoid derivatives
BRPI0413787A (pt) 2003-08-21 2006-11-07 Schering Ag delta 15-d-homoesteróides com efeito androgênico

Also Published As

Publication number Publication date
PT65821A (en) 1976-12-01
IL50854A (en) 1979-12-30
AU1943176A (en) 1978-05-18
DD128852A5 (de) 1977-12-14
ATA834476A (de) 1979-06-15
IL50854A0 (en) 1977-01-31
FR2331329A1 (fr) 1977-06-10
AT354653B (de) 1979-01-25
GB1564144A (en) 1980-04-02
NL7612538A (nl) 1977-05-13
IE43985B1 (en) 1981-07-15
PL193604A1 (pl) 1979-03-26
GR70298B (ja) 1982-09-06
MC1121A1 (fr) 1977-08-12
FR2331329B1 (ja) 1981-11-27
SU679147A3 (ru) 1979-08-05
LU76161A1 (ja) 1977-12-13
PT65821B (en) 1978-10-10
AU505624B2 (en) 1979-11-29
IE43985L (en) 1977-05-11
PH13603A (en) 1980-08-05
JPS5259148A (en) 1977-05-16
ES461325A1 (es) 1978-12-16
NZ182539A (en) 1979-07-11
DE2651364A1 (de) 1977-05-12
ES461326A1 (es) 1978-12-01

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Legal Events

Date Code Title Description
MKEX Expiry