CA1080823A - Centrifuge apparatus - Google Patents
Centrifuge apparatusInfo
- Publication number
- CA1080823A CA1080823A CA248,823A CA248823A CA1080823A CA 1080823 A CA1080823 A CA 1080823A CA 248823 A CA248823 A CA 248823A CA 1080823 A CA1080823 A CA 1080823A
- Authority
- CA
- Canada
- Prior art keywords
- whole blood
- hematocrit
- plasma
- red cell
- entrant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 210000004369 blood Anatomy 0.000 claims abstract description 72
- 239000008280 blood Substances 0.000 claims abstract description 72
- 238000005534 hematocrit Methods 0.000 claims abstract description 51
- 238000000034 method Methods 0.000 claims abstract description 15
- 230000001105 regulatory effect Effects 0.000 claims abstract description 6
- 238000000605 extraction Methods 0.000 claims description 10
- 239000000523 sample Substances 0.000 claims description 9
- 238000000926 separation method Methods 0.000 abstract description 16
- 210000004027 cell Anatomy 0.000 description 49
- 238000011084 recovery Methods 0.000 description 7
- 230000001276 controlling effect Effects 0.000 description 6
- 239000012530 fluid Substances 0.000 description 6
- 239000012503 blood component Substances 0.000 description 2
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 230000002572 peristaltic effect Effects 0.000 description 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000000332 continued effect Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3607—Regulation parameters
- A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
- A61M1/361—Physical characteristics of the blood, e.g. haematocrit, urea before treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3607—Regulation parameters
- A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
- A61M1/3612—Physical characteristics of the blood, e.g. haematocrit, urea after treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3669—Electrical impedance measurement of body fluids; transducers specially adapted therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
- A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0442—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
- B04B2005/0464—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation with hollow or massive core in centrifuge bowl
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Ecology (AREA)
- Centrifugal Separators (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/571,814 US3957197A (en) | 1975-04-25 | 1975-04-25 | Centrifuge apparatus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1080823A true CA1080823A (en) | 1980-07-01 |
Family
ID=24285179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA248,823A Expired CA1080823A (en) | 1975-04-25 | 1976-03-25 | Centrifuge apparatus |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3957197A (OSRAM) |
| JP (1) | JPS51130962A (OSRAM) |
| CA (1) | CA1080823A (OSRAM) |
| DE (1) | DE2617824A1 (OSRAM) |
| FR (1) | FR2308380A1 (OSRAM) |
| GB (1) | GB1517874A (OSRAM) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2551788A1 (de) * | 1975-11-18 | 1977-06-02 | Flottweg Werk Bruckmayer | Vollmantel-schneckenzentrifuge mit differenzdrehzahlvariabler kupplung zwischen mantelteil und schneckenteil |
| DE2551789A1 (de) * | 1975-11-18 | 1977-06-02 | Flottweg Werk Bruckmayer | Vollmantel-schneckenzentrifuge mit differenzdrehzahlvariabler kupplung zwischen mantelteil und schneckenteil |
| US4190321A (en) * | 1977-02-18 | 1980-02-26 | Minnesota Mining And Manufacturing Company | Microstructured transmission and reflectance modifying coating |
| US5006103A (en) * | 1977-08-12 | 1991-04-09 | Baxter International Inc. | Disposable container for a centrifuge |
| US5571068A (en) * | 1977-08-12 | 1996-11-05 | Baxter International Inc. | Centrifuge assembly |
| US5217427A (en) * | 1977-08-12 | 1993-06-08 | Baxter International Inc. | Centrifuge assembly |
| US5217426A (en) * | 1977-08-12 | 1993-06-08 | Baxter International Inc. | Combination disposable plastic blood receiving container and blood component centrifuge |
| US4185629A (en) * | 1977-10-18 | 1980-01-29 | Baxter Travenol Laboratories, Inc. | Method and apparatus for processing blood |
| DE3274800D1 (en) * | 1981-02-05 | 1987-02-05 | Asahi Chemical Ind | Apparatus for separating blood components |
| DE3301113C2 (de) * | 1983-01-14 | 1985-01-10 | Fresenius AG, 6380 Bad Homburg | Verfahren und Vorrichtung für das Separieren von Medien |
| DE3410286C2 (de) * | 1984-03-21 | 1986-01-23 | Fresenius AG, 6380 Bad Homburg | Verfahren zur Trennung von Blut sowie Vorrichtung zur Durchführung des Verfahrens |
| US4647279A (en) * | 1985-10-18 | 1987-03-03 | Cobe Laboratories, Inc. | Centrifugal separator |
| DE3601814A1 (de) * | 1986-01-22 | 1987-07-23 | Westfalia Separator Ag | Verfahren und vorrichtung zum trennen von zwei fluessigen phasen mittels einer zentrifuge |
| DE3632176A1 (de) * | 1986-09-22 | 1988-04-07 | Fresenius Ag | Steuerung eines systems zur trennung der bestandteile des einem spender "in vivo" entnommenen blutes |
| US5573678A (en) * | 1987-01-30 | 1996-11-12 | Baxter International Inc. | Blood processing systems and methods for collecting mono nuclear cells |
| US5370802A (en) * | 1987-01-30 | 1994-12-06 | Baxter International Inc. | Enhanced yield platelet collection systems and methods |
| US5641414A (en) * | 1987-01-30 | 1997-06-24 | Baxter International Inc. | Blood processing systems and methods which restrict in flow of whole blood to increase platelet yields |
| US5792372A (en) * | 1987-01-30 | 1998-08-11 | Baxter International, Inc. | Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma |
| US5656163A (en) * | 1987-01-30 | 1997-08-12 | Baxter International Inc. | Chamber for use in a rotating field to separate blood components |
| US5632893A (en) * | 1987-01-30 | 1997-05-27 | Baxter Internatinoal Inc. | Enhanced yield blood processing systems with angled interface control surface |
| US5628915A (en) * | 1987-01-30 | 1997-05-13 | Baxter International Inc. | Enhanced yield blood processing systems and methods establishing controlled vortex flow conditions |
| US4828716A (en) * | 1987-04-03 | 1989-05-09 | Andronic Devices, Ltd. | Apparatus and method for separating phases of blood |
| IT1203461B (it) * | 1987-04-08 | 1989-02-15 | Dideco Spa | Cella per la centrifugazione del sangue |
| US4850995A (en) * | 1987-08-19 | 1989-07-25 | Cobe Laboratories, Inc. | Centrifugal separation of blood |
| US4857811A (en) * | 1988-03-31 | 1989-08-15 | E. I. Du Pont De Nemours And Company | Evacuation pump control for a centrifuge instrument |
| DE3817664A1 (de) * | 1988-05-25 | 1989-11-30 | Josef Dr Theissen | Verfahren und vorrichtung zum waschen von blutzellen |
| US5078671A (en) * | 1988-10-07 | 1992-01-07 | Baxter International Inc. | Centrifugal fluid processing system and method |
| US4936820A (en) * | 1988-10-07 | 1990-06-26 | Baxter International Inc. | High volume centrifugal fluid processing system and method for cultured cell suspensions and the like |
| US5234608A (en) * | 1990-12-11 | 1993-08-10 | Baxter International Inc. | Systems and methods for processing cellular rich suspensions |
| DE4126341C1 (OSRAM) * | 1991-08-09 | 1993-01-28 | Fresenius Ag, 6380 Bad Homburg, De | |
| CA2103914A1 (en) * | 1991-12-23 | 1993-06-24 | Warren P. Williamson, Iv | Centrifugal processing system with direct access drawer |
| US5549834A (en) * | 1991-12-23 | 1996-08-27 | Baxter International Inc. | Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes |
| JP4065927B2 (ja) * | 1991-12-23 | 2008-03-26 | バクスター、インターナショナル、インコーポレイテッド | 分離チャンバーへのアクセスを提供する分離可能なボウル及びスプール要素を有する遠心機 |
| US5639382A (en) * | 1991-12-23 | 1997-06-17 | Baxter International Inc. | Systems and methods for deriving recommended storage parameters for collected blood components |
| US5690835A (en) * | 1991-12-23 | 1997-11-25 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
| US6007725A (en) * | 1991-12-23 | 1999-12-28 | Baxter International Inc. | Systems and methods for on line collection of cellular blood components that assure donor comfort |
| US5271852A (en) * | 1992-05-01 | 1993-12-21 | E. I. Du Pont De Nemours And Company | Centrifugal methods using a phase-separation tube |
| US5282981A (en) * | 1992-05-01 | 1994-02-01 | E. I. Du Pont De Nemours And Company | Flow restrictor-separation device |
| DE4308662C2 (de) * | 1993-03-18 | 1995-06-29 | Arno Henche | Vorrichtung zum Einsammeln von Spielbällen |
| DE69425966T2 (de) * | 1993-04-27 | 2001-03-29 | Haemonetics Corp., Braintree | Apheresisgerät |
| US5427695A (en) * | 1993-07-26 | 1995-06-27 | Baxter International Inc. | Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate |
| DE4340678C2 (de) * | 1993-11-30 | 2000-07-06 | Hettich Andreas Gmbh & Co Kg | Zentrifuge zur Trennung von Blutbestandteilen und ähnlichen Flüssigkeiten |
| US5961842A (en) * | 1995-06-07 | 1999-10-05 | Baxter International Inc. | Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit |
| US5637082A (en) * | 1996-02-22 | 1997-06-10 | Haemonetics Corporation | Adaptive apheresis apparatus |
| US5980760A (en) * | 1997-07-01 | 1999-11-09 | Baxter International Inc. | System and methods for harvesting mononuclear cells by recirculation of packed red blood cells |
| US6027657A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods for collecting diluted mononuclear cells |
| US6027441A (en) * | 1997-07-01 | 2000-02-22 | Baxter International Inc. | Systems and methods providing a liquid-primed, single flow access chamber |
| US7430478B2 (en) | 2000-03-01 | 2008-09-30 | Caridian Bct, Inc. | Blood processing information system with blood loss equivalency tracking |
| EP1238361A1 (en) * | 2000-03-01 | 2002-09-11 | Gambro, Inc. | Extracorporeal blood processing information management system |
| AU2002253801A1 (en) * | 2000-11-02 | 2002-08-19 | Gambro, Inc. | Fluid separation devices, systems and methods |
| US6890291B2 (en) * | 2001-06-25 | 2005-05-10 | Mission Medical, Inc. | Integrated automatic blood collection and processing unit |
| WO2003089926A2 (en) * | 2002-04-19 | 2003-10-30 | Mission Medical, Inc. | Integrated automatic blood processing unit |
| US7011631B2 (en) * | 2003-01-21 | 2006-03-14 | Hemonix, Inc. | Noninvasive method of measuring blood density and hematocrit |
| US9733805B2 (en) | 2012-06-26 | 2017-08-15 | Terumo Bct, Inc. | Generating procedures for entering data prior to separating a liquid into components |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3189180A (en) * | 1961-07-18 | 1965-06-15 | Shell Oil Co | Cyclone-centrifuge separator |
| US3489145A (en) * | 1966-08-08 | 1970-01-13 | Surgeon General Of The Public | Method and apparatus for continuous separation of blood in vivo |
| US3519201A (en) * | 1968-05-07 | 1970-07-07 | Us Health Education & Welfare | Seal means for blood separator and the like |
| SE324998B (OSRAM) * | 1969-02-28 | 1970-06-15 | Alfa Laval Ab | |
| US3772591A (en) * | 1972-04-12 | 1973-11-13 | Fisher Scientific Co | Method and apparatus for analyzing blood properties |
| US3829584A (en) * | 1972-08-21 | 1974-08-13 | Economics Lab | Continuous separating and standardizing of milk |
-
1975
- 1975-04-25 US US05/571,814 patent/US3957197A/en not_active Expired - Lifetime
-
1976
- 1976-03-25 CA CA248,823A patent/CA1080823A/en not_active Expired
- 1976-03-26 GB GB12183/76A patent/GB1517874A/en not_active Expired
- 1976-04-23 FR FR7612155A patent/FR2308380A1/fr active Granted
- 1976-04-23 DE DE19762617824 patent/DE2617824A1/de not_active Withdrawn
- 1976-04-26 JP JP51047618A patent/JPS51130962A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB1517874A (en) | 1978-07-12 |
| FR2308380B1 (OSRAM) | 1981-02-13 |
| JPS51130962A (en) | 1976-11-13 |
| DE2617824A1 (de) | 1976-11-04 |
| US3957197A (en) | 1976-05-18 |
| FR2308380A1 (fr) | 1976-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |