CA1069825A - Compositions and method of treating hypertension - Google Patents

Compositions and method of treating hypertension

Info

Publication number
CA1069825A
CA1069825A CA258,527A CA258527A CA1069825A CA 1069825 A CA1069825 A CA 1069825A CA 258527 A CA258527 A CA 258527A CA 1069825 A CA1069825 A CA 1069825A
Authority
CA
Canada
Prior art keywords
compound
alpha
dihydroxyphenyl
hydrazino
propionic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA258,527A
Other languages
English (en)
French (fr)
Inventor
Alexander Scriabine
Clement A. Stone
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1069825A publication Critical patent/CA1069825A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA258,527A 1975-08-13 1976-08-05 Compositions and method of treating hypertension Expired CA1069825A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/604,292 US4016288A (en) 1975-08-13 1975-08-13 Compositions and method of treating hypertension

Publications (1)

Publication Number Publication Date
CA1069825A true CA1069825A (en) 1980-01-15

Family

ID=24419029

Family Applications (1)

Application Number Title Priority Date Filing Date
CA258,527A Expired CA1069825A (en) 1975-08-13 1976-08-05 Compositions and method of treating hypertension

Country Status (10)

Country Link
US (1) US4016288A (enExample)
JP (1) JPS5225035A (enExample)
AU (1) AU508424B2 (enExample)
BE (1) BE845117A (enExample)
CA (1) CA1069825A (enExample)
DE (1) DE2636328A1 (enExample)
FR (1) FR2320738A1 (enExample)
GB (1) GB1505959A (enExample)
NL (1) NL7608381A (enExample)
ZA (1) ZA764852B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670578A (en) * 1983-08-29 1987-06-02 Merck & Co., Inc. Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
US20050136103A1 (en) * 2003-09-17 2005-06-23 Ben-Sasson Shmuel A. Compositions capable of facilitating penetration across a biological barrier
TWI755257B (zh) * 2014-10-21 2022-02-11 美商艾伯維有限公司 卡比多巴及左旋多巴之前藥及使用方法
CN111588833A (zh) * 2020-07-09 2020-08-28 北京大元藏宝堂健康管理有限公司 一种调节高血压的产品

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3830827A (en) * 1970-03-23 1974-08-20 Merck & Co Inc L-alpha-hydrazino-alpha-substituted-beta-(3,4-dihydroxyphenyl)propionic acid substantially free of the d isomer,the lower alkyl esters thereof,and the pharmaceutically acceptable salts thereof,wherein the substituent is lower alkyl
US3839585A (en) * 1970-08-05 1974-10-01 Merck & Co Inc Method of treating hypertension
AU464903B2 (en) * 1970-11-12 1975-09-11 Merck & Co., Inc Treatment of hypertension
US3795739A (en) * 1972-02-14 1974-03-05 Hoffmann La Roche Treatment of parkinson disease
US3784703A (en) * 1972-02-29 1974-01-08 Merck & Co Inc Method of treating hypertension

Also Published As

Publication number Publication date
ZA764852B (en) 1978-03-29
US4016288A (en) 1977-04-05
AU508424B2 (en) 1980-03-20
DE2636328A1 (de) 1977-02-24
NL7608381A (nl) 1977-02-15
AU1655876A (en) 1978-02-09
FR2320738B1 (enExample) 1979-05-18
FR2320738A1 (fr) 1977-03-11
JPS5225035A (en) 1977-02-24
BE845117A (fr) 1977-02-14
GB1505959A (en) 1978-04-05

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Legal Events

Date Code Title Description
MKEX Expiry