CA1067073A - Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloid - Google Patents
Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloidInfo
- Publication number
- CA1067073A CA1067073A CA242,012A CA242012A CA1067073A CA 1067073 A CA1067073 A CA 1067073A CA 242012 A CA242012 A CA 242012A CA 1067073 A CA1067073 A CA 1067073A
- Authority
- CA
- Canada
- Prior art keywords
- hydrogen
- alk
- formula
- hydroxyl
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53968175A | 1975-01-09 | 1975-01-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1067073A true CA1067073A (en) | 1979-11-27 |
Family
ID=24152219
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA242,012A Expired CA1067073A (en) | 1975-01-09 | 1975-12-18 | Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloid |
Country Status (13)
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR69783B (US06633782-20031014-M00005.png) * | 1976-09-08 | 1982-07-07 | Lilly Co Eli | |
| USRE30561E (en) | 1976-12-06 | 1981-03-31 | Eli Lilly And Company | Vinca alkaloid intermediates |
| GR68940B (US06633782-20031014-M00005.png) * | 1977-01-19 | 1982-03-29 | Lilly Co Eli | |
| US4191688A (en) | 1977-08-08 | 1980-03-04 | Eli Lilly And Company | Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine |
| US4195022A (en) | 1978-03-27 | 1980-03-25 | Eli Lilly And Company | 4-Desacetoxy-4α-hydroxyvinblastine and related compounds |
| US4166810A (en) | 1978-04-20 | 1979-09-04 | Eli Lilly And Company | Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide |
| US4199504A (en) * | 1978-05-15 | 1980-04-22 | Eli Lilly And Company | Bridged cathranthus alkaloid dimers |
| AR225153A1 (es) * | 1978-10-10 | 1982-02-26 | Lilly Co Eli | Un procedimiento para la preparacion de sulfato de vindesina |
| US4357334A (en) | 1980-03-20 | 1982-11-02 | Eli Lilly And Company | Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms |
| LU83822A1 (fr) * | 1981-12-08 | 1983-09-01 | Omnichem Sa | Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR204004A1 (es) * | 1973-04-02 | 1975-11-12 | Lilly Co Eli | Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina |
-
1975
- 1975-12-17 IL IL48685A patent/IL48685A/xx unknown
- 1975-12-18 CA CA242,012A patent/CA1067073A/en not_active Expired
- 1975-12-19 IE IE2775/75A patent/IE42385B1/en unknown
- 1975-12-19 PH PH17891A patent/PH17563A/en unknown
- 1975-12-22 DE DE19752558027 patent/DE2558027A1/de not_active Ceased
- 1975-12-29 CH CH1684075A patent/CH624962A5/de not_active IP Right Cessation
- 1975-12-31 NL NL7515253A patent/NL7515253A/xx not_active Application Discontinuation
-
1976
- 1976-01-06 GB GB281/76A patent/GB1538921A/en not_active Expired
- 1976-01-07 CS CS7699A patent/CS199615B2/cs unknown
- 1976-01-08 HU HU76EI664A patent/HU176226B/hu not_active IP Right Cessation
- 1976-01-08 BE BE1007122A patent/BE837390A/xx not_active IP Right Cessation
- 1976-01-09 JP JP51002380A patent/JPS5195100A/ja active Pending
- 1976-01-09 FR FR7600519A patent/FR2297043A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| FR2297043A1 (fr) | 1976-08-06 |
| FR2297043B1 (US06633782-20031014-M00005.png) | 1978-08-11 |
| CH624962A5 (en) | 1981-08-31 |
| IE42385L (en) | 1976-07-09 |
| NL7515253A (nl) | 1976-07-13 |
| JPS5195100A (US06633782-20031014-M00005.png) | 1976-08-20 |
| IE42385B1 (en) | 1980-07-30 |
| PH17563A (en) | 1984-10-01 |
| DE2558027A1 (de) | 1976-07-15 |
| HU176226B (en) | 1981-01-28 |
| BE837390A (fr) | 1976-07-08 |
| GB1538921A (en) | 1979-01-24 |
| IL48685A0 (en) | 1976-02-29 |
| CS199615B2 (en) | 1980-07-31 |
| IL48685A (en) | 1980-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4203898A (en) | Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids | |
| CA1042428A (en) | Amide derivatives of vlb and leurocristine | |
| CA1196326A (en) | Vinblastin-23-oyl amino acid derivatives | |
| CA1067073A (en) | Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloid | |
| US3944554A (en) | 4-Desacetoxy-3-hydroxyvinblastine | |
| US4191688A (en) | Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine | |
| CA1082179A (en) | Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloids | |
| US4115388A (en) | 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds | |
| CA1082180A (en) | Oxazolidinedione derivatives of vinca alkaloids | |
| US3887565A (en) | Vincadioline | |
| US4322351A (en) | Antineoplastic 4'-formylamino and 4'-acetylamino VLB, and derivatives thereof | |
| US4199504A (en) | Bridged cathranthus alkaloid dimers | |
| NZ202708A (en) | N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions | |
| US4160767A (en) | Vinca alkaloid intermediates | |
| Umarov et al. | Alkaloids of Thalictrum flavum: Structure of thalflavine | |
| US4279916A (en) | Method of treatment using new leurosine derivatives | |
| US4110330A (en) | 5'-Acetonylvincristine and related compounds | |
| USRE30560E (en) | Oxazolidinedione derivatives of Vinca alkaloids | |
| CA1061785A (en) | Acid and ester derivatives of vinblastine, vincristine and leurosidine | |
| US3890325A (en) | Leurocolombine | |
| CA1100956A (en) | 4-desacetoxy-4alpha-hydroxyvinblastine and related compounds | |
| CA1168231A (en) | 20'-hydroxyvinblastine and related compounds | |
| KR790000810B1 (ko) | 빈브라스틴 유도체의 제조방법 | |
| CA1121815A (en) | Bridged catharanthus alkaloid dimers | |
| AT345996B (de) | Verfahren zur herstellung neuer amidderivate von vinblastin, leurosidin und leurocristin und ihrer saeureadditionssalze |