CA1060800A - Anti-inflammatory composition containing potassium chloride - Google Patents
Anti-inflammatory composition containing potassium chlorideInfo
- Publication number
- CA1060800A CA1060800A CA249,337A CA249337A CA1060800A CA 1060800 A CA1060800 A CA 1060800A CA 249337 A CA249337 A CA 249337A CA 1060800 A CA1060800 A CA 1060800A
- Authority
- CA
- Canada
- Prior art keywords
- weight percent
- potassium chloride
- composition
- soap
- inflammatory composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
ABSTRACT OF THE DISCLOSURE
The present invention relates to an anti-inflammatory composition for topical application in the treatment of hyperaemia which comprises from 4 to 16 weight percent potassium chloride together with a pharmaceutically acceptable carrier.
The present invention relates to an anti-inflammatory composition for topical application in the treatment of hyperaemia which comprises from 4 to 16 weight percent potassium chloride together with a pharmaceutically acceptable carrier.
Description
` 10~t)80~
The invention relates to an anti-inflammatory composition for application particularly to the skin, mucous membrane and oral cavity to promote the flow of blood therein and alleviate the effects of hyperaemia.
The role played by potassium ions in cellular metabolism, and their action and uses in the body have been known for a long time (see, for example, The sritish Pharmacopoeia Codex 1968 pp 650 - ~51). Potassium ions are often administered to a patient by mouth or by intravenous injection in the form of aqueous solutions of potassium chloride.
The present invention, however, is based on the hitherto unexpected effects arising from the topical application of potassium ions in the form of potassium chloride to the outer surface of the skin or mucous membrane.
Thus, the present invention provides an anti-inflam-matory composition for topical application ln the treatment of hyperaemia which comprises from 4 to 16 weight percent potassium chloride together with a pharmaceutically acceptable carrier.
The application of the composition to the skin or mucous membrane has been found to speed up the circulation of blood in the external capillary blood vessels and lead to regeneration.
In particular the composition has been found effective in the treatment of hyperaemia, a conditon arising from an excess of ~uantity of blood in the skin tissues.
However, the composition has also been found to have a general anti-inflammatory effect and to assist the blood circulation in the skin tissues and, as such, has found use in the treatment of diseases of the mouth (stomatology), diseases of the skin (dermatology) and certain rheumatic diseases. In addition the composition has been found to exert a therapeutic effect in assisting granulation and healing of skin wounds.
~06~)8C)~
The pharmaceutically acceptable carrier is one of a wide range of such carriers suitable for topical application to the skin or mucous membrane (and including the oral cavity and gums) and well known to a man skilled in the art.
Embodiments of the invention will now be described by way of example only.
EXAMPLE I:
A composition for topical application, and particularly as a mouthwash, was made up by dissolving potassium chloride in distilled or tap water in the following proportions by weight:
4~, 8%, 12% and 16~.
EXAMPLE II:
A cream for application to the skin was made up by intimately mixing a composition consisting of 30 weight percent distilled water, 65 weight percent plant or animal grease and 5 weight percent potassium chloride.
EXAMPLE III:
A soap based composition was made up by mixing 85 weight percent of a soap with 15 weight percent potassium chloride.
EXAMPLE IV:
A soap based composition of lower viscosity and improved ease of application than that of Example III was made up by intimately mixing 50 weight percent of a soap, 38 weight per-cent dis~illed water and 12 weight percent potassium chloride.
EXAMæLE V:
A dental composition for application to the gums was made up by mixing 10 weight percent potassium chloride with a dental paste.
The invention relates to an anti-inflammatory composition for application particularly to the skin, mucous membrane and oral cavity to promote the flow of blood therein and alleviate the effects of hyperaemia.
The role played by potassium ions in cellular metabolism, and their action and uses in the body have been known for a long time (see, for example, The sritish Pharmacopoeia Codex 1968 pp 650 - ~51). Potassium ions are often administered to a patient by mouth or by intravenous injection in the form of aqueous solutions of potassium chloride.
The present invention, however, is based on the hitherto unexpected effects arising from the topical application of potassium ions in the form of potassium chloride to the outer surface of the skin or mucous membrane.
Thus, the present invention provides an anti-inflam-matory composition for topical application ln the treatment of hyperaemia which comprises from 4 to 16 weight percent potassium chloride together with a pharmaceutically acceptable carrier.
The application of the composition to the skin or mucous membrane has been found to speed up the circulation of blood in the external capillary blood vessels and lead to regeneration.
In particular the composition has been found effective in the treatment of hyperaemia, a conditon arising from an excess of ~uantity of blood in the skin tissues.
However, the composition has also been found to have a general anti-inflammatory effect and to assist the blood circulation in the skin tissues and, as such, has found use in the treatment of diseases of the mouth (stomatology), diseases of the skin (dermatology) and certain rheumatic diseases. In addition the composition has been found to exert a therapeutic effect in assisting granulation and healing of skin wounds.
~06~)8C)~
The pharmaceutically acceptable carrier is one of a wide range of such carriers suitable for topical application to the skin or mucous membrane (and including the oral cavity and gums) and well known to a man skilled in the art.
Embodiments of the invention will now be described by way of example only.
EXAMPLE I:
A composition for topical application, and particularly as a mouthwash, was made up by dissolving potassium chloride in distilled or tap water in the following proportions by weight:
4~, 8%, 12% and 16~.
EXAMPLE II:
A cream for application to the skin was made up by intimately mixing a composition consisting of 30 weight percent distilled water, 65 weight percent plant or animal grease and 5 weight percent potassium chloride.
EXAMPLE III:
A soap based composition was made up by mixing 85 weight percent of a soap with 15 weight percent potassium chloride.
EXAMPLE IV:
A soap based composition of lower viscosity and improved ease of application than that of Example III was made up by intimately mixing 50 weight percent of a soap, 38 weight per-cent dis~illed water and 12 weight percent potassium chloride.
EXAMæLE V:
A dental composition for application to the gums was made up by mixing 10 weight percent potassium chloride with a dental paste.
Claims (5)
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. An anti-inflammatory composition for topical application in the treatment of hyperaemia which comprises from 4 to 16 weight percent potassium chloride together with a pharmaceutically acceptable carrier selected from soap, dental paste and plant or animal grease.
2. A composition according to Claim 1, which consists of 30 weight percent distilled water, 65 weight percent plant or animal grease and 5 weight percent potassium chloride.
3. A composition according to Claim 1, which consists of 85 weight percent of a soap and 15 weight percent potassium chloride.
4. A composition according to Claim 1, which consists of 90 weight percent of a dental paste and 10 weight percent potassium chloride.
5. A composition according to Claim 1, which consists of 50 weight percent of a soap, 38 weight percent distilled water and 12 weight percent potassium chloride.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA249,337A CA1060800A (en) | 1976-04-01 | 1976-04-01 | Anti-inflammatory composition containing potassium chloride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA249,337A CA1060800A (en) | 1976-04-01 | 1976-04-01 | Anti-inflammatory composition containing potassium chloride |
Publications (1)
Publication Number | Publication Date |
---|---|
CA1060800A true CA1060800A (en) | 1979-08-21 |
Family
ID=4105607
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA249,337A Expired CA1060800A (en) | 1976-04-01 | 1976-04-01 | Anti-inflammatory composition containing potassium chloride |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA1060800A (en) |
-
1976
- 1976-04-01 CA CA249,337A patent/CA1060800A/en not_active Expired
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