CA1059905A - Compositions for preparation of aqueous solutions of low valence99 technetium salts - Google Patents
Compositions for preparation of aqueous solutions of low valence99 technetium saltsInfo
- Publication number
- CA1059905A CA1059905A CA262,178A CA262178A CA1059905A CA 1059905 A CA1059905 A CA 1059905A CA 262178 A CA262178 A CA 262178A CA 1059905 A CA1059905 A CA 1059905A
- Authority
- CA
- Canada
- Prior art keywords
- composition according
- group
- salt
- salts
- technetium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21H—OBTAINING ENERGY FROM RADIOACTIVE SOURCES; APPLICATIONS OF RADIATION FROM RADIOACTIVE SOURCES, NOT OTHERWISE PROVIDED FOR; UTILISING COSMIC RADIATION
- G21H5/00—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for
- G21H5/02—Applications of radiation from radioactive sources or arrangements therefor, not otherwise provided for as tracers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- High Energy & Nuclear Physics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2543349A DE2543349C2 (de) | 1975-09-29 | 1975-09-29 | Preaparate zur herstellung von99m technetium-radiagnostica |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1059905A true CA1059905A (en) | 1979-08-07 |
Family
ID=5957719
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA262,178A Expired CA1059905A (en) | 1975-09-29 | 1976-09-28 | Compositions for preparation of aqueous solutions of low valence99 technetium salts |
Country Status (13)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH630261A5 (de) * | 1977-09-08 | 1982-06-15 | Solco Basel Ag | Verfahren und ampulle zur herstellung von radiopharmazeutika. |
| US4233284A (en) * | 1978-03-31 | 1980-11-11 | The Procter & Gamble Company | Stabilized radiographic scanning agents |
| US4229427A (en) * | 1978-06-28 | 1980-10-21 | The Procter & Gamble Company | Radioactive scanning agents with hydroquinone stabilizer |
| US4232000A (en) * | 1978-06-28 | 1980-11-04 | The Procter & Gamble Company | Radioactive scanning agents with stabilizer |
| US4515766A (en) * | 1980-06-23 | 1985-05-07 | The Massachusetts General Hospital | Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium |
| DE3047107A1 (de) * | 1980-12-13 | 1982-07-29 | Hoechst Ag, 6000 Frankfurt | Verfahren zur hertellung von 1-amino-alkan-1,1-diphosphonsaeuren |
| US4504462A (en) * | 1982-06-10 | 1985-03-12 | Mallinckrodt, Inc. | Process for making a lyophilized product for use in skeletal imaging |
| US4440738A (en) * | 1982-06-10 | 1984-04-03 | Mallinckrodt, Inc. | Stable radiographic imaging agents |
| US4504463A (en) * | 1982-06-10 | 1985-03-12 | Mallinckrodt, Inc. | Process for making a lyophilized product for use in skeletal imaging |
| DE3237573A1 (de) * | 1982-10-09 | 1984-04-12 | Hoechst Ag, 6230 Frankfurt | Technetium-99m-tri- und tetraphosphonate zur szintigraphischen dastellung res-haltiger organe und der lymphgefaesse und verfahren zu deren herstellung |
| US4898724A (en) * | 1984-06-04 | 1990-02-06 | The Dow Chemical Company | Organis amine phosphonic acid complexes for the treatment of calcific tumors |
| US5066478A (en) * | 1984-06-04 | 1991-11-19 | The Dow Chemical Company | Radio labeled organic amine phosphonic acid complexes for the treatment of calcific tumors |
| IL74902A (en) * | 1984-06-04 | 1990-12-23 | Dow Chemical Co | Organic amine phosphonic acid complexes with particle-emitting radionuclides for the treatment of calcific tumors |
| US4687768A (en) * | 1984-12-21 | 1987-08-18 | The Procter & Gamble Company | Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism |
| US5104863A (en) * | 1984-12-21 | 1992-04-14 | The Procter & Gamble Company | Certain bicycloalkane and azabicycloalkane-1,1-diphosphonic acid derivatives useful for treating diseases associated with abnormal calcium and phosphate metabolism |
| US4830847A (en) * | 1985-06-28 | 1989-05-16 | The Procter & Gamble Company | Diphosphonate-derivatized macromolecules |
| JPS62185092A (ja) * | 1986-02-07 | 1987-08-13 | Teijin Ltd | 新規ホスホン酸誘導体および除草剤 |
| GB8615916D0 (en) * | 1986-06-30 | 1986-08-06 | Amersham Int Plc | Bone-seeking complexes of technetium-99m |
| US4868164A (en) * | 1986-12-19 | 1989-09-19 | Norwich Eaton Pharmaceuticals, Inc. | Octahydro-pyridine diphosphonate compounds, pharmaceutical compositions, and methods for treating abnormal calcium and phosphate metabolism |
| US5133956A (en) * | 1991-05-30 | 1992-07-28 | The Dow Chemical Company | Radiolabeled metal-binding protein for the treatment of arthritis |
| EP1191948A2 (en) | 1999-06-11 | 2002-04-03 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) * | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| WO2002062398A2 (en) | 2001-01-08 | 2002-08-15 | Neorx Corporation | Radioactively labelled conjugates of phosphonates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3989730A (en) * | 1972-06-15 | 1976-11-02 | Research Corporation | Bone-seeking technetium-99m complex |
| US3851044A (en) * | 1972-09-13 | 1974-11-26 | New England Nuclear Corp | Bone seeking technetium 99m stannous phosphate complex |
| US3965254A (en) * | 1973-05-23 | 1976-06-22 | The Procter & Gamble Company | Compositions for the treatment of calcific tumors |
| US3983227A (en) * | 1973-05-23 | 1976-09-28 | The Procter & Gamble Company | Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc99M containing bone scanning agents |
| US3976762A (en) * | 1974-07-05 | 1976-08-24 | Minnesota Mining And Manufacturing Company | Multi-organ technetium complexes production and use thereof |
| US3974268A (en) * | 1975-05-30 | 1976-08-10 | Research Corporation | Bone-seeking technetium-99m imidodiphosphonate complex |
-
1975
- 1975-09-29 DE DE2543349A patent/DE2543349C2/de not_active Expired
-
1976
- 1976-08-26 AU AU17185/76A patent/AU505502B2/en not_active Expired
- 1976-09-08 NL NL7609973A patent/NL7609973A/xx not_active Application Discontinuation
- 1976-09-10 DK DK408376A patent/DK408376A/da not_active Application Discontinuation
- 1976-09-23 US US05/725,883 patent/US4104366A/en not_active Expired - Lifetime
- 1976-09-27 BE BE170972A patent/BE846624A/xx not_active IP Right Cessation
- 1976-09-28 ZA ZA765814A patent/ZA765814B/xx unknown
- 1976-09-28 CH CH1226576A patent/CH622704A5/de not_active IP Right Cessation
- 1976-09-28 AT AT718276A patent/AT357688B/de not_active IP Right Cessation
- 1976-09-28 CA CA262,178A patent/CA1059905A/en not_active Expired
- 1976-09-28 GB GB40124/76A patent/GB1503439A/en not_active Expired
- 1976-09-29 FR FR7629195A patent/FR2325359A1/fr active Granted
- 1976-09-29 JP JP51117087A patent/JPS5244243A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| CH622704A5 (US08066781-20111129-C00013.png) | 1981-04-30 |
| DE2543349A1 (de) | 1977-04-07 |
| JPS5244243A (en) | 1977-04-07 |
| AT357688B (de) | 1980-07-25 |
| FR2325359A1 (fr) | 1977-04-22 |
| ZA765814B (en) | 1977-12-28 |
| GB1503439A (en) | 1978-03-08 |
| AU505502B2 (en) | 1979-11-22 |
| JPS6133807B2 (US08066781-20111129-C00013.png) | 1986-08-04 |
| AU1718576A (en) | 1978-03-02 |
| DK408376A (da) | 1977-03-30 |
| DE2543349C2 (de) | 1984-05-10 |
| US4104366A (en) | 1978-08-01 |
| FR2325359B1 (US08066781-20111129-C00013.png) | 1978-11-17 |
| BE846624A (fr) | 1977-03-28 |
| NL7609973A (nl) | 1977-03-31 |
| ATA718276A (de) | 1979-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA1059905A (en) | Compositions for preparation of aqueous solutions of low valence99 technetium salts | |
| US4247534A (en) | Radiographic scanning agent | |
| CA1059904A (en) | Compositions for preparation of aqueous solutions of salts of lower valence99 technetium | |
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| CA1122524A (en) | Stabilized radiographic scanning agents | |
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| EP0006659B1 (en) | Compositions useful in the preparation of stabilized radiographic scanning agents, a method of preparing them and the use of stannous gentisilate as stabilizer in these compositions | |
| US3983227A (en) | Dry mixture containing diphosphonates and a stannous salt useful in the preparation of Tc99M containing bone scanning agents | |
| US4497744A (en) | Gentisic acid salts as radiographic scanning agent stabilizers | |
| EP0096933B1 (en) | Process for making a lyophilized product for use in skeletal imaging | |
| CA1183774A (en) | Radioactive diagnostic agent for bone scanning and non-radioactive carrier therefor | |
| US4234562A (en) | Radiographic scanning | |
| EP0096931B1 (en) | Radiographic imaging agents | |
| EP0096932B1 (en) | Process for making a lyophilized product for use in skeletal imaging | |
| EP0096934B1 (en) | Radiographic imaging agents | |
| US4432963A (en) | Radiographic scanning agent | |
| CA1157033A (en) | Radiographic scanning agent | |
| Bevan | Radiographic scanning agent | |
| NZ209953A (en) | 99m technetatemethanehydroxydiphosphonate |